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RECCURENT GIANT CONDYLOMATA ACUMINATA CAUSED BY HUMAN PAPILLOMA VIRUS IN HIV WITH HOMOSEXUAL MALE Kusumaningsih, Emy; Setyowatie, Lita
Indonesian Journal of Tropical and Infectious Disease Vol. 8 No. 2 (2020)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v8i2.8375

Abstract

Perianal giant condylomata acuminate (GCA) is a rare clinical condition associated with low-risk Human papillomavirus (HPV) type 6 and 11 infections. Human Immunodeficiency Virus (HIV) infection is one of the risk factors for GCA, that can increase the condylomata acuminate incidence and spread caused by HPV. A 28-year-old man came with a cauliflower-like mass complaint in his perianal and anal since 2 months ago. The patient did not complain of pain or itching on the mass but often bled when defecating. The patient is a male who has sex with men (MSM) and often changes partners. He has been diagnosed with HIV since 11 months ago and regularly taking anti-retroviral drugs, Efavirenz 600 mg daily. He was also diagnosed having lung tuberculosis at the same time, got 6 months treatment and was declared cured. The venereological examination of the perianal and anal region revealed erythematous and grayish stem-shaped vegetation and papules, verrucous surface, multiple, well defined, with 3 x 1.5 x 2 cm in size. A positive act of white examination was obtained. Blood tests revealed CD+4 230 cells /μL. Polymerase chain reaction (PCR) examination for HPV obtained HPV types 6 and 11 infections. Histopathologic examination revealed acanthosis, papillomatosis, and hyperkeratotic epidermis and koilocytotic cells. The patient was treated with electrodesiccation three times but obtained mass in anal getting bigger with a size of 6 x 3 x 3 cm. Therefore, he agreed to be referred to the surgical department with an extensive surgical excision plan. Screening of GCA using PCR is not a routine examination but PCR has high sensitivity and specificity for determining the type of HPV, is useful for determining GCA prognosis and therapy, and is recommended for malignant and possible GCA recurrence detection
Efektivitas Edukasi Kesehatan terhadap Peningkatan Kesadaran Masyarakat dalam Pemilihan Krim Perawatan Kulit Yang Aman di RSUD Kabupaten Kediri Indasah, Indasah; Kusumaningsih, Emy; Khomsiyatin, Binti Ratna
Jurnal Pengabdian Masyarakat Bhinneka Vol. 3 No. 4 (2025): Bulan Juli
Publisher : Bhinneka Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58266/jpmb.v3i4.122

Abstract

Kulit adalah organ tubuh terbesar dalam tubuh manusia, yang melindungi dan menjaga integritas tubuh. Perawatan kulit, terutama wajah tentunya tidak lepas dari bahan kosmetik/krim perawatan kulit. Data Badan Pusat Statistik (2020) menunjukkan peningkatan pesat industri kosmetik di Indonesia sebesar 5,59% dan juga pasar kosmetik sebesar 7%, namun peningkatan ini tidak diimbangi pemahaman masyarakat tentang keamanan produk perawatan. Tujuan pengabdian masyarakat ini adalah memberikan edukasi kesehatan tentang pemilihanan krim perawatan kulit yang aman. Metode yang digunakan adalah penyuluhan dan diskusi interaktif tentang kesehatan kulit, jenis kulit, masalah kulit, pengertian tentang krim perawatan/kosmetik dan cara memilih krim yang aman terhadap pasien/pengantar pasien di Poliklinik Kulit, Kelamin dan Estetika Rumah Sakit Kabupaten Kediri. Dilakukan juga pembagian leaflet yang berisi informasi cara membaca komposisi, uji tempel kulit dan cara identifikasi krim perawatan yang aman serta informasi bahan berbahaya dalam kosmetik. Evaluasi menggunakan pretest dan posttest pada 22 peserta. Hasil menunjukkan peningkatan pengetahuan dari 86,36±13,57% menjadi 96,10±6,51% setelah edukasi. Uji Wilcoxon menunjukkan nilai signifikansi 0,000 (<0,05), membuktikan bahwa edukasi ini efektif meningkatkan kesadaran masyarakat dalam memilih krim perawatan kulit yang aman.