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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Pangan dan Hasil Pertanian Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Dinamisia: Jurnal Pengabdian Kepada Masyarakat Martabe : Jurnal Pengabdian Kepada Masyarakat Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia Jurnal Kreativitas PKM To Maega: Jurnal Pengabdian Masyarakat Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Ilmiah Farmako Bahari Parapemikir Jurnal Ilmiah Farmasi Jurnal Sains dan Kesehatan Jurnal Sains dan Teknologi Pangan
Novriyanti Lubis
Departemen Kimia Farmasi Analisis Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Garut
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Formulasi, Evaluasi, dan Perbandingan Intensitas Kepedasan Granul Effervescent Jahe Novriyanti Lubis; Riska Prasetiawati; Gilang Rahmat
Indonesian Journal of Pharmaceutical Science and Technology Vol 3, No 1 (2016)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.23 KB) | DOI: 10.24198/ijpst.v3i1.7911

Abstract

Telah dilakukan penelitian tentang formulasi, evaluasi, dan perbandingan intensitas kepedasan granul effervescent jahe putih (Zingiber officinale Roscoe) instan dan jahe merah (Zingiber officinale Var.Rubrum) instan yang menggunakan satu formulasi hasil dari estimasi. Metode yang digunakan ekstraksi panas yang digunakan untuk memperoleh ekstrak jahe instan dengan pengisi glukosa sebanyak 50% dari jumlah volum. Data pengamatan menunjukkan bahwa distribusi ukuran, bobot jenis benar, bobot jenis nyata, bobot jenis mampat, porositas, kompresibilitas, kadar air, kecepatan alir, dan sudut istirahat dari formula tetap stabil setelah penyimpanan selama 12 hari pada suhu ruangan. Hasil uji kepedasan dan kesukaan menyatakan bahwa granul effervescent jahe putih instan lebih pedas namun tidak memiliki aroma, warna yang kurang menarik, dibandingkan dengan granul effervescent jahe merah instan menurut para panelis relawan penguji. Kata kunci: Granul effervescent, intensitas kepedasan, jahe instan
Molecular Docking Study: Phyllanthus niruri L.'s Active Compounds as Dengue Haemorrhagic Fever Therapy Riska Prasetiawati; Silviyanita Isna Seftila; Benny Permana; Novriyanti Lubis
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 4, No. 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.42824

Abstract

Dengue Haemorrhagic Fever is a disease caused by the dengue virus through a mosquito vector Aedesaegypti. NS3 Helicase is known as one of nonstructural proteins consisting of some essential enzymesfor virus replication. Nowadays ivermectin has been developed as an anti-dengue haemorrhagic feverwith therapy target NS3 Helicase. The therapeutics drug for dengue haemorrhagic fever has not beenfound specifically. Methanol extract of meniran (Phyllanthus niruri L.) reported the activity to denguevirus with a concentration of 15,63 μg/mL. This research aimed to study the interactions and affinityof the active compound of meniran with the receptor (NS3 Helicase) and to know ADME and toxicityprofile. From 56 active compounds of meniran, there was one best candidate as dengue haemorrhagicfever therapy which has energy binding (ΔG) and Inhibition Constanta (IC) lower than native ligandand ivermectin, it is nirurin with energy binding -4.87 kcal/mol. These candidate compounds havegood absorption and distribution profiles so they are thought to be candidates for dengue fever therapyby targeting the NS3 Helicase receptor which is better than ivermectin and native ligands.
Co-Authors Abdullah Abdul Azfar Bin Mohd Roslan Atun Qowiyyah Benny Permana Citra Puja Effan Cahyati J Effan Cahyati Junaedi Effan Cahyati Junaedi Erina Aenia Farhatun Esty Rahayu Pangestika Fatimah Nasution Fatimah Nasution Gilang Rahmat Gugup Prasetiyo Idrus Kadir Ikbal Taufikurohman Ikbal Taufikurohman Ikbal Taufikurrohman Ilmiaty Rahmi Indah Eka Fariza Lindayani Lindayani Muhammad Arideira Muhammad Fadly Amin Muhammad Henli Saputra Nisa Shifa Abdillah Nova Savira Novita Rosalia Novita Rosalia Novita Rosilia Nuari, Doni Anshar Nur Syafiqah Binti Bakhitin Putri Widia Putri Widia Rahmayanti Rahmayanti Riska Prasetiawati Rizqi Ismail Al-Baasith Robi Asran Nugraha Robi Asran Nugraha Sandi Setiadi Seni Oktaviani Setiadi Ihsan Silviyanita Isna Seftila Siva Hamdani Sofi Sofiyani Soni, Dang Suryana, Shendi Sution Sution Sution Sution sution Syifa Aladawi Syifa Aladawi Syihabbudin Tiara Sri Yulviani Triana Ramadhanty Vingki Pratiwi Ganenggara Wita Nur Khairani