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Evaluation of Humoral Response of Emergency Unit Healthcare Workers after Third Dose of COVID-19 Vaccination Irsan, Abror; Mardhia, Mardhia; Rialita, Ambar
Muhammadiyah Medical Journal Vol 3, No 1 (2022): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.3.1.27-32

Abstract

Background:  Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is an emerging disease that has become pandemic. Healthcare workers are vulnerable persons due to SARS-CoV-2 infection. Healthcare workers are a government priority in the COVID-19 vaccine program. Antibody titer evaluation to healthcare workers as the first liner is essential due to the risk of the job. Purposes: The study aims to assess IgG antibody humoral response in healthcare workers in the emergency unit of Anton Soedjarwo Hospital, Pontianak, before and after the third dose of the COVID-19 vaccine. Methods: This study was a descriptive study with a cohort method. Twenty-two healthcare workers in the Emergency Unit in Anton Soedjarwo Hospital, Pontianak, participated in the study. Three ml venous blood samples were collected from the participants in two periods to quantify IgG antibody titer. The first period was before the third dose of the COVID-19 vaccine, and the second period was one month after the third dose of the COVID-19 vaccine. Chemiluminescent Microparticle Immunoassay (CMIA) methods were used to quantification IgG antibodies against spike-receptor binding domain (S-RBD) protein of SARS-CoV-2 Results: One month before the third dose of the COVID-19 vaccine, the majority of IgG antibodies show seropositivity (90.91%), with most on range 50-10,000 AU/ml (54.55%). Two participants (9.09%) show IgG antibodies less than 50 AU/ml (seronegative). One month after the third vaccination dose, all participants (100%) elicit IgG antibodies. Based on the comparison of IgG antibody titer before and after the third dose of the vaccine, the majority (68.18%) showed increasing the IgG antibody titer after the third vaccine.  Conclusion: The third dose vaccine might effectively elevate immune response to SARS-CoV-2 infection.
The Relationship between Personal Hygiene and the Incidence of Scabies Disease in Students at Al-Adabiy Islamic Boarding School, Pontianak Putri, Nurfaidah Sulistiningtyas Sugirah; Rahmayanti, Rahmayanti; Rialita, Ambar
Journal of Community Health Provision Vol. 4 No. 3 (2024): Journal of Community Health Provision
Publisher : PSPP JOURNALS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55885/jchp.v4i3.454

Abstract

Scabies is a skin disease that is influenced by the environment and personal hygiene. Caused by infestation and sensitization of Sarcoptes scabiei var. hominis. Symptoms of scabies are complaints of itching at night, with clinical signs of papules or vesicles, the peak is like a tunnel in the predilection area, grayish white, straight or curved. The objective of this study was to determine the relationship between personal hygiene and the incidence of scabies in students at the Al-Adabiy Pontianak Islamic Boarding School in 2023. The research design used in this study was observational analytic with a cross-sectional approach conducted on 60 students of Al-Adabiy Islamic Boarding School using a simple random sampling technique, hypothesis testing using Fisher's test. The results showed that respondents who had scabies were in the age range of 12-16 years (65%), were in class X (50%) and were dominated by males (60%). 85% of students had poor personal hygiene with a scabies incidence rate of 33.3%. The results of the Fisher's test obtained a significance value (sig.) of 0.023 (p <0.05). There is a relationship between personal hygiene and the incidence of scabies.
Aktivitas antijamur isolat bakteri endofit tanaman kunyit (Curcuma longa L.) terhadap penghambatan pertumbuhan Candida albicans Prasetyo, Raditia Tri; Rialita, Ambar; Mahyarudin, Mahyarudin
Jurnal Pendidikan Informatika dan Sains Vol. 13 No. 2 (2024): Jurnal Pendidikan Informatika dan Sains
Publisher : IKIP PGRI Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31571/saintek.v13i2.7957

Abstract

Candidiasis adalah infeksi kulit yang disebabkan oleh jamur, terutama spesies Candida albicans. Sebagian besar kasus candidiasis saat ini menunjukkan resistensi terhadap obat antijamur yang ada, sehingga diperlukan pencarian senyawa metabolit baru sebagai alternatif antijamur. Bakteri endofit, mikroorganisme yang hidup di dalam jaringan tumbuhan tanpa menyebabkan kerusakan, diketahui memiliki potensi untuk menghasilkan senyawa kimia yang berfungsi sebagai antijamur. Penelitian ini bertujuan untuk mengevaluasi dan mengidentifikasi aktivitas antijamur dari mikroorganisme endofit yang diisolasi dari tanaman kunyit (Curcuma longa L.) terhadap C. albicans. Desain penelitian yang digunakan adalah deskriptif. Aktivitas antijamur terhadap C. albicans diuji menggunakan metode difusi cakram. Dari 17 isolat endofit yang diuji, 8 isolat menunjukkan aktivitas penghambatan dengan zona hambat berkisar antara 7,16 hingga 10,6 mm. Isolat yang paling potensial, yakni isolat M2, diidentifikasi memiliki kesamaan genus dengan Pseudomonas. Analisis senyawa metabolit sekunder pada isolat M2 mengungkapkan keberadaan saponin, terpenoid, dan flavonoid sebagai senyawa antijamur. Dengan demikian, isolat endofit dari tanaman kunyit terbukti memiliki potensi untuk menghambat pertumbuhan C. albicans, sehingga tanaman kunyit dapat menjadi pilihan alternatif pengobatan secara tradisional dan menjadi salah satu sumber potensial dalam perkembangan di bidang farmasi.
DETERMINAN KEJADIAN DEMAM BERDARAH DENGUE (DBD) DI WILAYAH KOTA PONTIANAK TAHUN 2019 Zhafira, Tasya Fathia; Kahtan, M Ibnu; Rialita, Ambar
Kieraha Medical Journal Vol 7, No 1 (2025): KIERAHA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran, Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/kmj.v7i1.9230

Abstract

Latar belakang: Demam Berdarah Dengue (DBD) merupakan penyakit infeksi oleh virus Dengue yang sering terjadi di Indonesia dengan kejadian luar biasa dan tingkat kematian besar. Ada banyak faktor yang berhubungan dengan kejadian DBD, diantaranya faktor pengetahuan, sikap, perilaku dan peran petugas kesehatan. Kota Pontianak merupakan salah satu daerah endemis penyakit Demam Berdarah Dengue (DBD). Tujuan: Mengetahui determinan kejadian demam berdarah dengue di wilayah Kota Pontianak Tahun 2019. Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Sampel yang digunakan berjumlah 44 orang. Hasil: Hasil analisis didapatkan ada hubungan antara pengetahuan dan tindakan dengan kejadian DBD di Pontianak Tahun 2019 (p=0,0040,05), tidak ada hubungan antara sikap masyarakat, dukungan petugas kesehatan dan pengalaman mendapat penyuluhan dengan kejadian DBD di Pontianak Tahun 2019. Kesimpulan: Pengetahuan dan tindakan masyarakat merupakan determinan kejadian DBD di wilayah Kota Pontianak Tahun 2019.