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All Journal Callosum Neurology Journal : Jurnal Berkala Neurologi Bali ISM (Intisari Sains Medis) : Jurnal Kedokteran JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga AKSONA
Ardiansyah, Djohan
Department Of Neurology, Faculty Of Medicine Airlangga University/Dr. Soetomo General Hospital, Surabaya, East Java, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : AKSONA

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Profile of Meningioma Patients at Dr. Soetomo General Academic Hospital Valeryna, Natasha; Ardiansyah, Djohan; Susanto, Joni; Utomo, Sri Andreani
AKSONA Vol. 4 No. 2 (2024): JULY 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v4i2.53334

Abstract

Highlight: Meningioma, the most common primary brain tumor, is typically found in women aged 40-49 years old. Meningiomas can show distinctive characteristics on clinical, radiological, and histopathological examinations. There were significant differences in histopathological grading between male and female patients, as well as between homogenous and heterogenous contrast enhancement.   ABSTRACT Introduction: Meningioma is an intracranial extracranial tumor that arises from arachnoid cells. It is reported to be the most common primary brain tumor (39%). Meningioma is diagnosed based on clinical and radiological findings, but a definitive diagnosis requires histopathology examination. However, the clinical, radiological, and histopathological profile of meningioma is rarely studied in Indonesia. Objective: This study aimed to identify the clinical, radiological, and histopathological profile of meningioma patients at Dr. Soetomo General Academic Hospital Surabaya from 2017 to 2021. Methods: This was a retrospective observational study with a cross-sectional design using secondary data collected from electronic medical records at Dr. Soetomo General Academic Hospital Surabaya in 2017-2021. Results: A total of 256 patients were included in this study. The majority of the patients in this study were female (83.98%), aged 40-49 years old (43.36%), and mostly had the clinical symptom of headache (35.94%). Meningiomas were mostly WHO grade I (85.16%), with a transitional subtype (44.92). Based on the Kruskal-Wallis test, there were differences in histopathological grading between male and female patients (p = 0.000), as well as between homogenous and heterogenous tumor enhancement (p = 0.027). However, there were no differences in histopathological grading between the dural tail findings (p = 0.181) and hyperostosis findings (p = 0.135). Conclusion: Meningioma was found to be more common in females than in males, with the peak occurring in 40-49 years old. The most prevalent clinical symptom was headache, and convexity was the most common location for these tumors, most of which were larger than 3 cm. The majority of meningiomas were WHO grade I with transitional subtype.   
Profile of Stroke Patients in John Piet Wanane General Hospital Sorong: A Descriptive Study Ardiansyah, Djohan; Ruma, Agustinus; Luhur, Lu Jordy
AKSONA Vol. 5 No. 2 (2025): JULY 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v5i2.56139

Abstract

Highlight: Hypertension is the leading risk factor for cardiovascular disease and stroke. Blood pressure variability, including early morning surge, increases stroke risk. Low education is associated with an increased risk of stroke due to limited health literact and lifestyle challenges.   ABSTRACT Introduction: Stroke has become the major cause of physical disability in adults and the second leading cause of death in middle- to high-income countries. Indonesia has the second-highest mortality rate and stroke burden in Southeast Asia. Furthermore, there is limited study on stroke in eastern Indonesia, especially in Papua. Objective: This study aimed to evaluate the clinical profile of stroke patients treated in John Piet Wanane General Hospital. Methods: This descriptive, hospital-based study was conducted at John Piet Wanane General Hospital, Sorong, Southwest Papua, from August 1, 2023, to January 31, 2024. Data were collected  through interviews and the identification of  subjects’ medical records based on inclusion and exclusion criteria. Results: This study involved a total of 143 patients, with an average age of 58.17 ± 10.516 years. The gender distribution was nearly equal, with 52.4% women and 47.6% men. The subjects mainly had an overweight Body Mass Index (BMI) (39,2%) or a normal BMI (36.4%). Obesity and underweight were the least common with percentage of 18.9%% and 5.6% of subjects, respectively. Hypertension (75.5%), prior stroke (33.6%), and hyperlipidemia (33.6%) were the most frequently found among subjects. Diabetes mellitus was found in 29.4% of subects, followed by smoking (28.7%), a history of heart disease (21%), and alcohol consumption (14.7%).  Ischemic stroke was the most prevalent type of stroke (65.7%), followed by intracerebral hemorrhage (23,8%), transient ishcemic attack (TIA) (5.6%), subarachnoid hemorrhage (2.8%), and pontine hemorrhage (2.1%). Conclusion:This study revealed that ischemic stroke was the predominant subtype, while pontine hemorrhage was rare. Hypertension emerged as the most common risk factor, followed by prior stroke, hyperlipidemia, and diabetes mellitus, highlighting the substantial burden of modifiable vascular risk factors.  
Co-Authors Duta Angela DYAH FAUZIAH, DYAH Fauzan, Rizki Ahmad Joni Susanto, Joni Luhur, Lu Jordy Machin, Abdulloh Ruma, Agustinus Sri Andreani Utomo, Sri Andreani Suprabawati, Desak Gede Agung Valeryna, Natasha Vita Kusuma Rahmawati