Studi Islam modern menghadapi kompleksitas sosial, budaya, politik, dan ilmu pengetahuan kontemporer yang tidak dapat dijawab hanya dengan pendekatan normatif-teologis. Penelitian ini bertujuan mengeksplorasi urgensi, implementasi, dan tantangan pendekatan interdisipliner dalam pengembangan studi Islam modern. Metode yang digunakan adalah studi literatur dengan menelaah karya-karya akademik mengenai integrasi ilmu keislaman dengan ilmu sosial, humaniora, dan sains. Hasil penelitian menunjukkan bahwa pendekatan interdisipliner memperluas pemahaman Islam secara komprehensif, baik dalam kajian tafsir, hadis, dan fiqh, maupun dalam praktik kurikulum di PTKIN dan sekolah berbasis Islam. Tantangan yang muncul meliputi resistensi dari kalangan konservatif, keterbatasan sumber daya akademik, serta konflik metodologis antar disiplin. Kebaruan penelitian ini terletak pada sintesis teori interdisipliner Nissani, paradigma integrasi-interkoneksi Amin Abdullah, dan konsep kolaborasi epistemik Miller yang menegaskan interdisipliner bukan sekadar pilihan metodologis, melainkan paradigma strategis dalam membangun studi Islam yang lebih dinamis, inklusif, dan solutif. This discussion explores the interdisciplinary approach in the development of modern Islamic studies as a response to the complexity of contemporary social, cultural, political, and scientific realities. Islamic studies, which previously focused on normative-theological approaches, are now required to open themselves to the integration of various other disciplines such as sociology, anthropology, politics, economics, and even environmental science and technology. This paper outlines the urgency of an interdisciplinary approach in Islamic studies as an effort to answer the challenges of the times and increase the relevance and contribution of Islam in modern life. The implementation of an interdisciplinary approach can be seen through the integration of social science methods and perspectives in the study of interpretation, hadith, and fiqh, as well as in the development of curricula in Islamic educational institutions. However, this approach also faces various challenges, such as resistance from conservatives, limited academic resources, and methodological conflicts between disciplines. This study emphasizes that an interdisciplinary approach is not just a methodological choice, but a strategic need for the advancement of dynamic, contextual, and solution-oriented Islamic studies in the modern era.