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All Journal ALKIMIA : Jurnal Ilmu Kimia dan Terapan Odonto dental journal
Putri, Salsabila Aqila
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Medicine & Pharmacology Social Sciences

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Ultrasonic Extraction of Nothaphoebe Coriacea Bark and Its Antioxidant Evaluation Putri, Salsabila Aqila; Febrianti, Ratih; Nisa, Khoirun; Sunardi, Sunardi
ALKIMIA Vol 4 No 2 (2020): ALKIMIA
Publisher : SCIENCE AND TECHNOLOGY FACULTY OF UNIVERSITAS ISLAM NEGERI RADEN FATAH PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.139 KB) | DOI: 10.19109/alkimia.v4i2.7333

Abstract

Nothaphoebe coriacea (in Kalimantan, Indonesia, commonly known as gemor) is a native wetland-plants that can grow well in swampy areas. This tree is distributed throughout South and Central Kalimantan, Indonesia. The bark of Nothaphoebe coriacea is used for bioactive compound source for larvacide, mosquito repellent, hio and glue. The objective of this research was to investigate the ultrasound-assisted extraction methods for the extraction of antioxidants compounds of Nothaphoebe coriacea. The barks were subjected to ultrasound‐assisted ethanolic and hexane extraction followed by fractionation (using ethyl acetate, chloroform, and hexane) and the antioxidant activity test was performed. The activity of antioxidant was carried out through a DPPH method. The highest antioxidant activities are shown in ethanol extract with IC50 value of 72.36 μg/mL and chloroform fraction of ethanol extract with IC50 value of 54.18 μg/mL.
Potential Natural Antibacterial Agent for P. gingivalis Periodontitis Infection: A Comprehensive Review of Source, Structure and Mechanism actions Amin, Meiny Faudah; Ariwibowo, Taufiq; Putri, Salsabila Aqila; Kurnia, Dikdik
Odonto : Dental Journal Vol 11, No 1 (2024): July 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.1.146-158

Abstract

The pathogenic bacteria P. gingivalis grows in the oral cavity. This bacterium could attack immune system which lead to inflammation of most tissues. P. gingivalis can cause a variety of serious and dangerous condition such as periodontitis, Alzheimer, rheumatoid arthritis, diabetes, and pneumonia. Antibiotics have been used for years as a treatment against this bacterium, like metronidazole, amoxicillin, and clindamycin, however, P. gingivalis is reported to be resistant to these antibiotics, thus exploration to discover alternatives has been demanded. Natural product compounds are known to have antibacterial activity and cause fewer side effects. Turmeric, eucalyptus, and several other plants have been reported to have antibacterial activity against P. gingivalis with a MIC of 1g/mL from an ethyl acetate leaf extract of eucalyptus. Decent antibacterial activity could be used as a reference to discover new drugs as alternatives against P. gingivalis
Co-Authors Dikdik Kurnia Febrianti, Ratih Khoirun Nisa Meiny Faudah Amin Sunardi Sunardi Taufiq Ariwibowo