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Evaluation and Antibacterial Activity Test of Peel-off Mask Preparation from Combination of Pegagan Leaves (Centella asiatica (L) Urb.) and Charcoal Powder Utari, Fadhilla Dwi; Hilaliyati, Najmi; Afriani, Tika
Biology, Medicine, & Natural Product Chemistry Vol 13, No 1 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.131.127-133

Abstract

Pegagan leaf (Centella asiatica (L) Urb.) is a plant that contains flavonoids, tannins, triterpenoids, and saponins that function as antibacterials. Pegagan leaf is combined with activated charcoal powder, which has the job of absorbing facial oil, so that it is formulated in the form of a peel off mask to produce a synergistic effect. This study aims to formulate, evaluate, and test the antibacterial effectiveness of the peel-off mask preparation of pegagan leaf extract at concentrations of 1.5%, 2%, and 2.5%. This study uses an experimental method by testing the parameters of the physical evaluation requirements and testing antibacterial activity with the disc method on the peel off mask preparation. The results were evaluated for 28 days, and the results of the organoleptic test were stable, homogeneity stable, pH (5.6–6.2), dry time (16–25 minutes), dispersion (6.1-6.4 cm), and irritation (2 respondents). The effectiveness test against the bacteria Propionibacterium acnes has inhibitory power of 12.3 mm in the strong category. So, it can be concluded that the peel off mask produced has stable physical characteristics and can be used as an antibacterial mask.
17-2 Variasi Penggunaan Beeswax Lip Balm Stik dari Ekstrak Kulit Nanas (Ananas comosus (L.) Merr.) Hilaliyati, Najmi; Resi Rizki Banjarani; Muhammad Arif; Nursyafni; Widiya Ismail
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 17 No. 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lip balm is a preparation applied to the lips to prevent dryness and chapping. Choosing the right lip balm base will significantly impact its quality and public acceptability. Beeswax has good binding properties, which help to produce a homogeneous mass. In this study, the active ingredient used was pineapple peel because it contains bromelain, which moisturizes the lips. The objectives of this study were to determine the appropriate formulation for lip balm preparations with pineapple peel extract (Ananas comosus (L.) Merr.) as the active ingredient and to determine the effect of varying beeswax base concentrations on the physical stability of lip balm preparations. The method used in this study was an experimental method to see which formulation was suitable. The study obtained a good formula with physical characteristics in accordance with SNI 16-4769-1998, including stability observation, pH measurement, homogeneity testing, irritation testing, moisture testing, and cycling test. The appropriate formula was found in formula 1 with a beeswax concentration of 1%, which produced a good color texture, aroma, adhesive power, and spreadability, a pH level suitable for the lips, no irritation, homogeneity, and stability during storage, resulting in a semi-solid and very smooth lip balm texture when used