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All Journal Media Publikasi Promosi Kesehatan Indonesia (MPPKI) IPTEK: Jurnal Hasil Pengabdian kepada Masyarakat
Leman, Yanti
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Agriculture, Biological Sciences & Forestry Arts Humanities Computer Science & IT Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Public Health Social Sciences Other

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Edukasi Pencegahan Penyakit Menular Seksual dan HIV/AIDS bagi Remaja di Kota Makassar Arif, Sitti Musafirah; Makmur, Andi Amal Alamsyah; Leman, Yanti; Amiruddin, Dianawaty
IPTEK: Jurnal Hasil Pengabdian kepada Masyarakat Vol 5, No 1 (2025): IPTEK: Jurnal Hasil Pengabdian kepada Masyarakat
Publisher : Univeristas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26858/iptek.v5i1.76585

Abstract

Abstrak. Remaja merupakan generasi penerus bangsa yang tengah berada dalam masa transisi menuju kedewasaan, sehingga menghadapi tantangan kompleks baik secara fisik, emosional, maupun sosial. Minimnya dukungan dan informasi sering membuat remaja rentan terhadap perilaku berisiko, termasuk hubungan seksual pranikah yang berpotensi menularkan Penyakit Menular Seksual (PMS). Data BPS (2024) menunjukkan peningkatan signifikan perilaku seksual pranikah di kalangan remaja Indonesia, yang memperbesar risiko penyebaran PMS seperti HIV/AIDS, sifilis, dan HPV. Menanggapi kondisi ini, dilakukan kegiatan edukasi di SMK Telkom Makassar untuk membekali remaja dengan pengetahuan mengenai jati diri, kesehatan mental, dan pencegahan PMS. Metode yang digunakan berupa ceramah dan diskusi interaktif, dengan materi meliputi pengenalan jati diri, penyebab dan gejala PMS dan HIV/AIDS, serta cara pencegahan dan peran remaja sebagai educator sebaya. Hasil kegiatan menunjukkan peningkatan pemahaman siswa terhadap risiko PMS dan HIV/AIDS dan pentingnya menjaga kesehatan reproduksi, serta antusiasme untuk menjadi agen edukasi di lingkungan sekolah. Edukasi yang komprehensif berbasis penguatan jati diri terbukti efektif dalam membentuk kesadaran, sikap bertanggung jawab, dan ketahanan remaja dalam menghadapi tantangan perkembangan zaman. Kata Kunci: remaja, penyakit menular seksual, edukasi kesehatan reproduksi
Utilization of Fucoidan Based on Nanodelivery in Health Promotion Perspective, Molecular Mechanism, and Community Empowerment: A Scoping Review Alexandraa, Francisca Diana; Massi, Muh. Nassrum; Leman, Yanti; Manggau, Marianti A.; Frethernety, Agnes; Jayanti, Ira
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 8 No. 12: DESEMBER 2025 - Media Publikasi Promosi Kesehatan Indonesia (MPPKI)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v9i1.9131

Abstract

Introduction: Fucoidan is a sulfated polysaccharide derived from brown algae with proven anticancer, antioxidant, and immunomodulatory properties. However, its clinical utilization remains limited due to high molecular weight and low bioavailability. Recent advances in nanodelivery systems provide promising strategies to overcome these limitations and align with community-based health promotion initiatives. Methods: This scoping review adopted the PEOS framework (Population, Exposure, Outcome, Study Design) and PRISMA flow to map current evidence on fucoidan’s molecular mechanisms, nanocarrier innovations, and community empowerment perspectives. Literature searches were conducted in PubMed, ScienceDirect, EBSCO, and Google Scholar from 2015–2023 using keywords “fucoidan,” “nanoparticle,” “nanocarrier,” “molecular mechanism,” and “health promotion.” Twenty-three eligible articles were critically appraised using Hawker’s Quality Assessment Tool. Results: Fucoidan exhibits anticancer effects through upregulation of Bax, downregulation of Bcl-2, activation of caspases, and inhibition of angiogenesis via NF-?B, MAPK, and Nrf2 signaling pathways. Nanodelivery systems including chitosan fucoidan nanoparticles, PEGylated PLGA, hydrogels, and microneedle patches enhanced stability, absorption, and targeted efficacy. Preclinical studies demonstrated tumor inhibition, wound healing, and immunomodulatory benefits. From a public health perspective, fucoidan-based nanotechnology supports health promotion through increased scientific literacy, integration into Health Promoting Hospitals, and economic empowerment of coastal communities producing brown algae. Conclusion:Fucoidan represents a multifunctional bioactive compound whose efficacy is strengthened by nanodelivery innovation. Integrating molecular insights with health promotion and community empowerment creates a sustainable model linking biotechnology, preventive health, and local economic development. This review emphasizes the importance of interdisciplinary collaboration in translating marine biopolymers into accessible, evidence-based complementary therapies.
Co-Authors Alexandraa, Francisca Diana Amiruddin, Dianawaty Arif, Sitti Musafirah Frethernety, Agnes Jayanti, Ira Makmur, Andi Amal Alamsyah Marianti A Manggau Massi, Muh. Nassrum