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Siregar, Indra Basar
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Dentistry Medicine & Pharmacology

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Effectivity of Mengkudu (Morinda citrifolia) Fruit Extract in Inhibiting the Growth of Streptococcus viridans Causing Dry Socket Post Extraction Dohude, Gostry Aldica; -, Ahyar Riza; Siregar, Indra Basar; -, Ayu Lestari
Journal of Syiah Kuala Dentistry Society Vol 9, No 1 (2024): June 2024
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v9i1.37845

Abstract

Background: Post-extraction wound healing usually proceeds but sometimes has problems and causes complications in the form of a dry socket. Streptococcus viridans bacterial infection is one of the causes of dry socket, therefore prevention of infection can be done by providing antibiotic or antibacterial (antiseptic) therapy. Noni fruit (Morinda citrifolia) contains many phenols, saponins, and alkaloids that can potentially be antibacterials. Objective: This study aims to determine the effectiveness of noni (Morinda citrifolia) extract against Streptococcus viridans bacteria in post-extraction sockets. Methods: This type of research is a laboratory experiment with Post test only control group design, where this study uses the Kirby-Bauer diffusion method with Streptococcus viridans bacteria samples and uses noni fruit extract (Morinda citrifolia) with concentrations of 3.125%, 6.25%, 12.5%, 25%, and 50%; Positive control Chlorhexidine digluconate 0.2%; And negative control DMSO. Results: The data analysis using Kruskal-Wallis showed a p-value of 0.000 on inhibition, which showed that noni fruit extract could inhibit the growth of Streptococcus viridans bacteria. Conclusion: Noni fruit extract (Morinda citrifolia) effectively inhibits the growth of Streptococcus viridans bacteria with an effective dose of 50%, but the antibacterial activity is still below the activity of Chlorhexidine gluconate 0.2%.
Effectiveness of Wuluh Starfruit Leaf (Averrhoa bilimbi Linn) Extract on The Growth Streptococcus mutans In Vitro Riza, Ahyar; Hayati, Fitrah; Siregar, Indra Basar; Oes, Abdullah
Journal of Syiah Kuala Dentistry Society Vol 8, No 2 (2023): December 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i2.33676

Abstract

Background: Starfruit (Averrhoa bilimbi Linn) contains vitamin C, flavonoids, tannins, and triterpenoids. This active compound is reported to prevent the growth of bacteria, including Streptococcus mutans. Objective: This study aims to determine the effectiveness of starfruit leaf extract (Averrhoa bilimbi Linn) in inhibiting Streptococcus mutans. Method: This type of research is true experimental with a post-test-only control design, where this research uses the Kirby-Baur diffusion method with samples of Streptococcus mutans bacteria and uses wuluh leaf extract with concentrations of 50%, 25%, 12.5%, 6 .25%, 3.125%. And DMSO solution as a negative control. Results: The formation of a clear zone shows the ability of starfruit leaf extract to inhibit the growth of Streptococcus mutans, with an average inhibitory diameter of 12.05 0.7188, 9.50 0.3464.8, 65 0.2380, 7.80 0.4546, 6.78 0.8016. Conclusion: Based on the research results, it can be concluded that Averrhoa bilimbi Linn can inhibit Streptococcus mutans.
Effectiveness of Ethanol Extract of Eugenia polyantha Wigh in Inhibiting Streptococcus mutans Syaflida, Rahmi; Riza, Ahyar; Siregar, Indra Basar; Ravichandran, Pavitra
Journal of Syiah Kuala Dentistry Society Vol 8, No 1 (2023): June 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i1.33342

Abstract

Background: Many microorganisms can be found within the oral cavity, including Streptococcus mutans. The introduction of oral bacteria into the bloodstream can lead to the occurrence of bacteremia and subsequent development of systemic diseases. Traditional medicine uses specific ingredients or herbs employed over successive generations and is widely believed to possess medicinal properties. One example is the bay leaf, scientifically known as Eugenia polyantha Wight. Objective. This study aims to determine the effectiveness of bay leaf extract (Eugenia polyantha Wight.) in inhibiting Streptococcus mutans. Materials and Methods: This type of research is an experimental laboratory with Post-test Only Control Group Design. Testing the effectiveness of antibacterial in this study using the diffusion method by diluting bay leaf extract using DMSO solvent into five concentrations, namely 50%, 25%, 12.5%, 6.25%, and 3.125%, with a sample size of 4 for each concentration. Results: The results showed that bay leaf extract concentrations of 50%, 25%, 12.5%, 6.25%, and 3.125% showed a clear zone around the disc paper in Muller Hinton Agar as a medium for the breeding of Streptococcus mutans bacteria. The formation of a clear zone indicates that the ability of bay leaf extract inhibits the growth of Streptococcus mutans with a mean diameter of inhibition of 10.4 0.2944 mm; 8.9 0.7500 mm; 7.1 0.3202 mm; 6.9 0.2944 mm; and 6.4 0.1826 mm. Conclusion: Eugenia polyantha Wight can inhibit the development of Streptococcus mutans. A concentration of 50% is the best in inhibiting the development of Streptococcus mutans based on the growth zone of bacteria.
Antimicrobial Assessment of Curcuma longa L Against Streptococcus mutans Growth Dohude, Gostry Aldica; Isnandar, Isnandar; Siregar, Indra Basar; Tanzia, Allisha
Journal of Syiah Kuala Dentistry Society Vol 8, No 1 (2023): June 2023
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v8i1.33031

Abstract

Background. Streptococcus mutans is the most common oral endogenous microorganism found at the beginning of plaque formation until the formation of dental caries. If not handled properly, caries can lead to odontogenic infections. Increased resistance to antimicrobial drugs has made herbal ingredients an alternative treatment because they are more effective and do not cause side effects. This turmeric leaf contains active antimicrobial compounds of flavonoids, tannins, and phenolics. Objective. This study aimed to determine the effectiveness of turmeric leaf extract (Curcuma longa. L) as an antimicrobial on the growth of Streptococcus mutans bacteria. Materials and Methods. This study uses a post-test-only control condition approach in a laboratory setting. The concentration of turmeric leaf extract tested was 10%, 15%, and 20% with the positive control (Chlorhexidine 0,2% mouthwash) and negative control (DMSO) with five repetitions. Antibacterial effectiveness test using serial dilution method. Results. The data analysis using the Oneway ANOVA test showed a p-value 0.05, meaning that the number of Streptococcus mutans bacterial colonies in both the treatment and control groups had a significant difference in number. The antibacterial effect at a 10% concentration of turmeric leaf extract (Curcuma longa. L) with an average and standard deviation of 45.20 3.83, at a 15% concentration of 43.80 3.11, at a 20% concentration of 23.60 12.30. Conclusion. This study concludes that turmeric leaf extract (Curcuma longa. L) has antibacterial effectiveness against Streptococcus mutans bacteria.Keywords: Curcuma longa L, Turmeric Leaf, Streptococcus mutans, Antibacterial
Co-Authors -, Ahyar Riza -, Ayu Lestari Dohude, Gostry Aldica Fitrah Hayati Isnandar Oes, Abdullah Ravichandran, Pavitra Riza, Ahyar Syaflida, Rahmi Tanzia, Allisha