Article Per Year (5 Year)
p-Index From 2021 - 2026
1.203
P-Index
This Author published in this journals
All Journal Journal of Tropical Biodiversity and Biotechnology BIOEDUSCIENCE Spektra: Jurnal Fisika dan Aplikasinya
Handayani, Windri
Unknown Affiliation
Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Electrical & Electronics Engineering Energy Environmental Science Immunology & microbiology Materials Science & Nanotechnology Physics

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : bioeduscience

 1 
Zooremediation: Utilizing Animals for Environmental Purification and Pollution Mitigation Aini, Fadita Nurul; Nisa, Upi Chairun; Handayani, Windri; Maryenti, Tety; Yasman, Yasman
BIOEDUSCIENCE Vol 9 No 2 (2025): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/18376

Abstract

Background: The global human population continues to grow rapidly, leading to increasing urban waste and environmental contamination. One emerging and promising approach to mitigating this pollution is zooremediation, which utilizes animals as biological agents for environmental cleanup. This review aims to critically assess the effectiveness of various animal species in removing specific classes of pollutants, with particular attention to their mechanisms of action—zooextraction, zootransformation, and zooaccumulation—and the environmental conditions under which they operate. Effectiveness is evaluated based on pollutant removal efficiency, adaptability to contaminated environments, and ecological safety. Methods: Through systematic literature analysis, we identified key species, including Geukensia demissa, Daphnia magna, and Anadara granosa, which demonstrated measurable success in the remediation of aquatic environments contaminated with heavy metals and organic pollutants. Additionally, soil-dwelling nematodes such as Caenorhabditis elegans and Cephalobus persegnis play critical roles in hydrocarbon degradation and in enhancing microbial synergy in polluted substrates. These findings highlight the diverse functional capacities of animals in bioremediation efforts. The methodology employed in this study is a comprehensive literature review, focusing on peer-reviewed articles published over the last two decades. Results: This review synthesizes findings related to pollutant types, animal species used in zooremediation, remediation outcomes, and ecological impacts. By critically examining existing studies, the evaluation identifies trends, gaps, and challenges in the application of zooremediation. Conclusion: Future research should focus on understanding the long-term impacts, optimizing protocols, and safeguarding both ecological and animal health to fully realize the potential of zooremediation in managing environmental pollution on a global scale.
Comparative Study of The Physiological Condition of Six Tree Species to Air Pollution in Depok City, West Java Ayunda, Ajenk; Yuniati, Ratna; Handayani, Windri
BIOEDUSCIENCE Vol 7 No 2 (2023): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/9749

Abstract

Background: Air pollution is a threat to the environment. Sources of air pollutants in urban environments can be in the form of dust, heavy metals, and hydrocarbons. Plants can help clean air pollutants from the atmosphere by absorption through the stomata, accumulating them, or by adsorption on the leaf surface. The Air Pollution Tolerance Index (APTI) is used as an evaluation benchmark for the Physiological conditions of plants exposed to air pollution. This research aims to study the physiological conditions of six tree species in air conditions in the Depok City area and to assess the plants' tolerance level based on the APTI calculation. Methods: The physiological parameters measured to calculate APTI were ascorbic acid, total chlorophyll, leaf extract pH, and Relative Water Content (RWC). The six tree species used as objects in this study were Artocarpus altilis, Artocarpus heterophyllus, Bauhinia purpurea, Ficus septica, Filicium decipiens, and Nephelium lappaceum. Results: Differences in the physiological conditions of six tree species in the Depok City area based on the average ascorbic acid values, total chlorophyll, leaf extract pH, and RWC. In addition, there are also differences in APTI parameters between the two research locations. Conclusions: Filicium decipiens is the plant species with the highest APTI, while Artocarpus heterophyllus has the lowest. Based on the APTI scores, Bauhinia purpurea, Ficus septica, Filicium decipiens, Nephelium lappaceum belong to moderately tolerant category, Artocarpus altilis belongs to an intermediate category, Artocarpus heterophyllus belongs to sensitive category.
Metabolite Profiling and Bioprospecting of Acrolejeunea fertilis (Reinw., Blume & Nees) Schiffn. from Kebun Raya Cibodas, West Java Ramadhani, Nadhifa Tazkia; Handayani, Windri; Yasman, Yasman; Putrika, Afiatry
BIOEDUSCIENCE Vol 8 No 1 (2024): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/13187

Abstract

Background: Acrolejeunea fertilis (liverwort) is known for having various potential natural products. However, its abundance is limited, and its secondary metabolites have not been extensively investigated. The in vitro culture technique might enhance its biomass. Methods: This study aimed to investigate the metabolite profile of A. fertilis from Kebun Raya Cibodas grown in situ and in vitro. The bioactivity, including antioxidant, total phenolic, and flavonoid content and antibacterial activity, was also evaluated. The in vitro culture of A. fertilis used ½ MS media with the addition of 0,1 mg/L of 2,4-D and one mg/L of Kinetin. Methanol and n-hexane were used for extraction. Gas Chromatography-Mass spectrometry (GC-MS) is used for metabolite profiling. Results: The optimum IC50 value from n-hexane extract is 68,18±2,65 mg/L. The highest yield of total phenolic and flavonoid content from in situ methanol extract, which resulted in 130,68±0,002 µgGAE/gr and 5,97±0,01 µgQE/gr, respectively. Antibacterial activities were evaluated by measuring the zone of inhibition for S. aureus and E. coli. The optimum area measured from in situ n-hexane extract was 23,91±1,54 and 13,08±0,23 cm, respectively. Conclusions: These findings carry important implications for the further development of natural products obtained from liverwort regarding its potential as a bioactive compound.
Exploring the Pharmacological Potential of Centella asiatica: A Metabolomic Perspective on a Traditional Medicinal Plant Aini, Fadita Nurul; Yuwana, Cynthia Putri; Maryenti, Tety; Nisa, Upi Chairun; Yuniati, Ratna; Handayani, Windri; Yasman, Yasman
BIOEDUSCIENCE Vol 10 No 1 (2026): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/18857

Abstract

Background: Centella asiatica, also known as Gotu Kola or Pennywort, is a medicinal herb with a long history of use in traditional systems such as Mediterranean Herbal Medicine, Ayurveda, and Traditional Chinese Medicine. Its longstanding use highlights its importance as a natural remedy for various health conditions.   Methods: Recent metabolomics-based studies have advanced our understanding of its pharmacological potential by identifying key bioactive compounds—including phenolics, triterpenoids, and saponins—through analytical techniques such as GC-MS, LC-MS, and NMR.   Results: These compounds contribute to a range of therapeutic effects, notably antioxidant and antibacterial activities. C. asiatica has demonstrated efficacy against antibiotic-resistant pathogens like Staphylococcus aureus and Pseudomonas aeruginosa, as well as the ability to mitigate oxidative stress.   Conclusions: The integration of pharmacological and metabolomics approaches has highlighted its potential for development into herbal medicines and health supplements. While further research is warranted to optimize formulation and clinical application, existing evidence provides a solid foundation for the advancement of C. asiatica as a natural product for promoting human health and addressing antimicrobial resistance.
Co-Authors Adhi Harmoko Saputro Aini, Fadita Nurul ASIH PERWITA DEWI, ASIH PERWITA Atria, Mega Ayunda, Ajenk Baidlowi, Muhammad Hisyam Dian Rosleine, Dian Irsyam, Arifin Surya Dwipa Maryenti, Tety Muhammad Rifqi Hariri Nisa, Upi Chairun Panggabean, Prima Ria Rumata Peniwidiyanti, Peniwidiyanti Putrika, Afiatry Ramadhani, Nadhifa Tazkia Rista, Rista Tianara, Alexander Yasman Yasman Yuniati, Ratna Yuwana, Cynthia Putri