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Milasari, Novi
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ANALISIS KADAR FENOLIK TOTAL DAN FLAVONOID TOTAL EKSTRAK ETANOL KULIT PISANG KEPOK (Musa pradisiaca L) Ariani, Novia; Prihandiwati, Erna; Rahim, Aulia; Milasari, Novi; Fatimah, Nurul
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1614

Abstract

Banana peel is a very large amount of waste material (banana fruit waste). In general, banana peels have not been used optimally. Based on the research results, kepok banana peel contains secondary metabolites in the form of flavonoids, alkaloids, tannins and saponins. This study aims to determine the total phenolic content and total flavonoid content of the ethanol extract of kepok banana skin (Musa pradisiaca L). Extraction was carried out by maceration method with 96% ethanol solvent. Determination of total phenol content used the Folin-Ciocalteu method with gallic acid as comparator compound and the determination of total flavonoid content used the colorimetric method with 10% AlCl3 and 5% acetic acid as reagents. The results showed that kepok banana peel extract had an average total phenolic content of 13.4495 mg GAE/g ± 1.5473206 and an average total flavonoid content of 8.5468 mg QE/g ± 0.947422695.
UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA EKSTRAK METANOL KULIT BUAH MARKISA UNGU (Passiflora edulis f. edulis Sims) DENGAN SPEKTROFOTOMETRI UV-VIS Sundu, Reksi; Jubaidah, Siti; Milasari, Novi; Adhila, Ghina
JFM (Jurnal Farmasi Malahayati) Vol 8, No 2 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i2.21642

Abstract

Tabir surya dapat membantu mencegah efek buruk radiasi ultraviolet. Efektivitas tabir surya didasarkan pada penentuan nilai Sun Protection Factor (SPF) yang menunjukkan kemampuan produk tabir surya dalam melindungi kulit dari paparan sinar UV. Nilai SPF besar atau kecil dipengaruhi oleh kandungan antioksidan dan bahan aktif yang digunkan dalam membuat sediaan tabir surya. Antioksidan alamiah tubuh berfungsi sebagai sistem pertahanan untuk melindungi sel-selnya dari kerusakan yang disebabkan oleh radikal bebas. Ekstrak kulit buah markisa ungu mengandung senyawa karotenoid, polifenol, dan vitamin. Tujuan dari penelitian ini untuk mengetahui aktivitas antioksidan dan tabir surya ekstrak methanol kulit buah markisa ungu (Passiflora edulis f. edulis Sims). Metode penelitian menggunakan metode DPPH secara Spektrofotometri UV-Vis. Metode Penelitianmenggunakan metode DPPHsecara Spektrofotometri UV-Visc Hasil penelitian menunjukkan metabolit sekunder yang terdapat dalam ekstrak metanol kulit markisa ungu flavonoid, tanin, saponin, alkaloid, dan terpenoid. Aktivitas antioksidan ekstrak metanol kulit markisa ungu didapatkan nilai IC50 sebesar 125,13 ±13,22 termasuk dalam kategori sedang dan pembanding vitamin C sebesar 7,17 ± 0,60 termasuk dalam ketegori sangat kuat. Nilai tertinggi SPF terdapat pada konsentrasi 2.000 ppm yaitu 30,03 ± 0,24 dan termasuk dalam kategori tinggi
Pelatihan Pembuatan Cheese Cake Labu Kuning (Cucurbita moschata Duch.) sebagai Alternatif Makanan Fungsional dalam Pencegahan Stunting di Poyandu Kemuning, Sambutan Adhila, Ghina; Milasari, Novi; Sundu, Reksi; Namira, Nadine Anastasya Putri; Rachman, Nadya Rahmawati; Rachmanissa, Nadya; Nabila, Annisa Bela; Dhevani, Apria Audya; Ananda, Anugrah
Jurnal Pengabdian Masyarakat Bangsa Vol. 3 No. 10 (2025): Desember
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v3i10.3516

Abstract

Stunting disebabkan oleh kurangnya asupan gizi secara kronis, terutama selama periode 1.000 hari pertama kehidupan (HPK), yang berdampak pada terganggunya pertumbuhan fisik dan perkembangan kognitif anak. Salah satu upaya pencegahan stunting yang dapat dilakukan adalah dengan memanfaatkan bahan pangan lokal bergizi tinggi, seperti labu kuning (Cucurbita moschata Duch.) yang mengandung beta-karoten, vitamin A, C, serat, dan mineral. Labu kuning memiliki potensi sebagai bahan makanan fungsional, dalam hal pembuatan MPASI. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan masyarakat dalam pencegahan stunting melalui edukasi gizi dan pelatihan pengolahan labu kuning menjadi cheesecake sehat. Kegiatan dilaksanakan pada tanggal 2 Juni 2025 di Posyandu Kemuning, Kelurahan Sambutan, Kota Samarinda, dengan melibatkan 15 peserta yang terdiri dari kader posyandu, ibu dan balita. Metode yang digunakan meliputi penyuluhan interaktif, demonstrasi memasak, serta evaluasi melalui kuesioner. Hasil pengabdian menunjukkan peningkatan pemahaman peserta terhadap kondisi stunting, 75% peserta berada dalam kategori baik, 22% cukup, dan 3% kurang. Penyampaian materi secara praktis dan penggunaan media edukatif yang menarik dinilai efektif dalam meningkatkan keterlibatan peserta. Program ini membuktikan bahwa integrasi edukasi gizi dengan praktik pengolahan pangan lokal dapat menjadi strategi efektif dalam pencegahan stunting.
UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL UMBI BAWANG DAYAK (Eleutherine palmifolia) TERHADAP MENCIT YANG DIINDUKSI KARAGENIN Milasari, Novi; Adhila, Ghina; Syamsul, Eka Siswanto
Jurnal Riset Kefarmasian Indonesia Vol. 7 No. 1 (2025): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v7i1.679

Abstract

            Inflammation is a normal response to protect tissue injury from toxic chemicals, physical trauma, or microbial agents. Treatment of inflammation generally uses synthetic drugs, but the use of these drugs in addition to eliminating inflammation also has many side effects and is relatively expensive. Therefore, anti-inflammatory drugs derived from plants are used. One of the natural medicines used is Dayak onion (Eleutherine palmifolia) because empirically it is widely used by the Dayak and Kutai communities, which has the potential as a medicinal plant with various enormous properties. This study aimed to determine the anti-inflammatory activity of an ethanol extract of Dayak onion bulbs (Eleutherine palmifolia) in carrageenin-induced mice. The test of anti-inflammatory activity was carried out by forming artificial inflammation on the soles of the feet of white mice. The study was conducted on 15 mice, which were divided into 5 groups. The first group as a negative control was given a 0.5% CMC solution. The second group as a positive control was given diclofenac sodium at a dose of 27 mg/ 20 g BW. The third, fourth, and fifth groups were given a dayak onion bulb extract dose of 100 mg /kgBB, 200 mg /kgBB, and 400 mg /kgBB. Based on the measurement of the percent inhibition of inflammation from the 30th minute to the 300th minute, it was found that the average dose of Dayak onion extract 1 (100 mg/KgBB) had the lowest percent inhibition of inflammation, which was 23.064±1.286%, dose 2 was 37.701±2.354%, and dose 3 was 52.324±4.751% and positive control of 76.348±8.702% which has the highest percent of inflammation inhibition. Based on the study, it can be concluded that the ethanol extract of dayak onion bulbs has the best anti-inflammatory activity at dose 3 of 52.324±4.751% in mice induced by carrageenin.
PENGARUH SUPLEMENTASI MINYAK SAWIT MERAH TERHADAP KADAR HS-CRP TIKUS MALNUTRISI Astani, Ameliora; Milasari, Novi; Rosalina, Rosalina; Supriono, Supriono
Jurnal Riset Kefarmasian Indonesia Vol. 7 No. 3 (2025): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/v7i3.847

Abstract

Red palm oil (RPO) is a processed product derived from oil palm that is rich in β-carotene, a precursor of vitamin A. Vitamin A is known to play a beneficial role in reducing inflammatory responses, which are among the risk factors that exacerbate stunting. This study aimed to evaluate the effectiveness of RPO in reducing levels of the inflammatory marker high-sensitivity C-reactive protein (Hs-CRP). It is expected that RPO supplementation may help suppress inflammation, thereby contributing to the improvement of nutritional status. An in vivo experimental design was employed using male Sprague Dawley rats, which were divided into five groups: a healthy control group (K+), a malnourished group (K−), and three treatment groups receiving RPO at different dosages (P1: 0.16 ml/200 g BW/day; P2: 0.26 ml/200 g BW/day; and P3: 0.56 ml/200 g BW/day). The intervention lasted for eight weeks, consisting of a four-week malnutrition induction phase followed by a four-week RPO supplementation phase. RPO administration resulted in a significant increase in body weight among the malnourished rats in all treatment groups (P1, P2, and P3) (p < 0.05). However, Hs-CRP levels did not show statistically significant changes following RPO supplementation in malnourished rats. The potential of red palm oil in mitigating malnutrition warrants further investigation by considering inflammatory markers and conducting a comprehensive analysis of vitamin A status.
Antioxidant Activity Test of Tampoi Fruit Peel Extract (Baccaurea pyriformis Gage) using the DPPH (2,2-Difenil-1-Pkrihidrazil) Method Milasari, Novi; Reksi Sundu, Reksi Sundu; Hayatus Sa’adah, Hayatus Sa’adah; Stevani Olivia, Stevani Olivia; Adhila, Ghina; Fatimah, Nurul
Jurnal Riset Kefarmasian Indonesia Vol. 8 No. 1 (2026): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v8i1.908

Abstract

Excessive oxidation reactions in the body can cause various harmful effects, mainly due to the uncontrolled production of free radicals. Antioxidant compounds are needed to protect the body from free radical attacks. One natural source of antioxidants is the tampoi fruit (Baccaurea pyriformis Gage). This fruit is known to contain metabolites such as flavonoids, phenolics, tannins, and saponins, which act as natural antioxidants. The purpose of this study was to determine the antioxidant activity of tampoi fruit peel (Baccaurea pyriformis Gage) using the DPPH method. This was an experimental study with the independent variable being ethanol extract of tampoi fruit peel and the dependent variable being antioxidant activity. The research stages included plant determination, slimpisia preparation, maceration extraction, phytochemical screening, determination of extract moisture content, and antioxidant activity testing with DPPH. The results showed a drying shrinkage of 5.6%, an extract yield of 13%, and an extract moisture content of 14.77%, which is classified as a thick extract. Phytochemical screening showed the presence of alkaloids, flavonoids, tannins, and saponins. Antioxidant test results showed that tampoi fruit peel ethanol extract had an average IC value of 11.8165 ppm (very strong category), and vitamin C as a comparison had an IC value of 7.5019 ppm. Thus, tampoi fruit peel ethanol extract has strong antioxidant activity.
Co-Authors Adhila, Ghina Ananda, Anugrah Ariani, Novia Astani, Ameliora Dhevani, Apria Audya Eka Siswanto Syamsul Hayatus Sa’adah, Hayatus Sa’adah Nabila, Annisa Bela Namira, Nadine Anastasya Putri Nurul Fatimah Prihandiwati, Erna Rachman, Nadya Rahmawati Rachmanissa, Nadya Rahim, Aulia Reksi Sundu Reksi Sundu, Reksi Sundu Rosalina Rosalina Siti Jubaidah, Siti Stevani Olivia, Stevani Olivia Supriono Supriono