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All Journal Damianus Journal of Medicine Ophthalmologica Indonesiana
Casey, Anthea
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Health Professions Medicine & Pharmacology Public Health

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Neuromyelitis Optica Spectrum Disorder (NMOSD): Challenges and Updates Iskandar, Ferdy; Priscilia, Florentina; Casey, Anthea; Sidik, Mohamad
Bahasa Indonesia Vol 23 No 3 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i3.3973

Abstract

Pendahuluan: Neuromyelitis optica spectrum disorder (NMOSD) merupakan kondisi autoimun yang ditandai dengan inflamasi pada nervus optikus, saraf spinal, dan sistem saraf pusat. Meskipun NMOSD memiliki angka prevalensi yang relatif rendah, prognosis visual penyakit ini cukup buruk dan laju relapsnya tinggi. Tinjauan pustaka ini diharapkan dapat mendorong pembaca untuk bisa mendiagnosis secara lebih dini untuk menentukan tatalaksana serangan akut dan mencegah serangan berikutnya sesuai dengan kompetensi kedokteran. Metode: Artikel ini disusun berdasarkan kepustakaan yang diperoleh dari database Google Scholar, PubMed, dan ProQuest, menggunakan kata kunci “neuromyelitis optica spectrum disorder” dari publikasi tahun 2012 sampai dengan tahun 2022. Hasil: Penyebab NMOSD hingga saat ini masih tidak diketahui dengan pasti, namun diduga disebabkan oleh kondisi sistem imun humoral di dalam tubuh menyerang astrosit. Kriteria diagnosis NMOSD didasarkan pada konsensus yang dikeluarkan oleh International Panel for Neuromyelitis Optica Diagnosis. Myelitis akut, neuritis optik yang berat, muntah dan cegukan berulang merupakan gejala khas pada NMOSD. Lesi myelitis transversal ekstensif longitudinal merupakan penemuan khas pada magnetic resonance imaging (MRI). Tatalaksana NMOSD pada fase akut berupa kortikosteroid dosis tinggi, sedangkan pada fase pemeliharaan berupa imunosupresan. Kejadian relaps ditemukan pada 90% pasien dan komplikasi yang terjadi dapat berupa disabilitas visual, disabilitas motorik, hingga kematian. Simpulan: Diagnosis NMOSD ditegakkan berdasarkan penemuan klinis, pencitraan, dan laboratorium. Tatalaksana yang tepat dan adekuat berguna untuk mencegah disabilitas dan morbiditas di kemudian hari.
OVERVIEW OF PATIENTS SCREENED FOR AND DIAGNOSED WITH ROP IN PEDIATRIC OPHTHALMOLOGY OUTPATIENT CLINIC BEFORE, DURING, AND AFTER THE COVID-19 PANDEMIC: Poster Presentation - Observational Study - Ophthalmologist BARLIANA, JULIE DEWI; Sitorus, Rita Rita; Yulia, Dian Estu; Casey, Anthea; Zahra, Raihanny Andrea
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/hwpgv162

Abstract

Introduction & Objectives : The COVID-19 pandemic has profoundly impacted healthcare systems worldwide, leading to significant changes in the delivery of medical services. Non-urgent ophthalmology visits were canceled. However, premature infants at risk of retinopathy of prematurity (ROP) require timely and in-person care to prevent vision loss. This study aims to report on the high-risk babies screened and diagnosed with ROP before, during, and after the COVID-19 pandemic Methods : This is a descriptive study conducted on premature infants who visited the pediatric ophthalmology outpatient clinic at Cipto Mangunkusumo Hospital Jakarta between January 2019 and December 2022. Data was collected using medical records and presented using tables and charts Results : A total of 368 babies were screened for ROP in 2019, and 75% were diagnosed with ROP. During the lockdown in 2020, the number of babies screened for ROP decreased to 286, and the incidence of ROP was 38.5%. In 2021 and 2022, ROP screening increased to 458 and 515 babies per year, respectively. After the COVID-19 pandemic subsided, ROP screenings increased significantly from 2020 to 2021. The number of babies screened in 2021 and 2022 was similar, but the incidence of ROP decreased from 45.4% in 2021 to 20.3% in 2022 Conclusion : This study highlights the impact of the COVID-19 pandemic on ROP screening and diagnosis in a pediatric ophthalmology outpatient clinic. After the COVID-19 pandemic, the number of babies screened for ROP increased due to the end of the lockdown
Co-Authors Estu Yulia, Dian Iskandar, Ferdy Julie Dewi Barliana Priscilia, Florentina Sidik, Mohamad Sitorus, Rita Rita Zahra, Raihanny Andrea