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Different Effects of Hylocecarus Polyrhizus and Hylocecarus Undatus Extract on Reducing Total Cholesterol of Male Rattus Norvegicus Wistar Strain Fahriani, Elviza; Mylano, Tri Adi; Hutapea, Johnson
Journal La Medihealtico Vol. 5 No. 2 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i2.1100

A chronic ailment that is caused by excessive food consumption and a lack of physical activity, obesity is a condition that may be prevented. The tropical dragon fruit can control cholesterol levels, support the immune system, and give a natural colorant for culinary applications. In a true experimental research, sample with rats were fed red and white dragon fruit extracts to determine the amounts of cholesterol in their bodies. Spectrophotometry was used to determine the rats' blood lipid profiles, cholesterol levels, and body weight after they were fed a meal that was high in fat and contained duck egg yolk. For this study, extracts from red and white dragon fruits were administered to male Wistar rats to determine their effects on cholesterol levels. After fourteen days, both groups had a reduction in high cholesterol levels, with group 4 exhibiting the most significant drop in cholesterol levels. Additionally, the extracts decreased the levels of MDA while simultaneously increasing the levels of SOD. The most significant rise was seen in group 4, given white dragon fruit extract at 140 mg/200 gr BW daily. SPSS was utilized to analyze the effects of dragon fruit on blood cholesterol levels in experimental animals, employing the LSD technique and one-way ANOVA.

Factors influencing the occurrence of neck pain complaints in garment convection tailors Siregar, Damayanti; Handoko, Ellya Keriahen; Setiawan, Deni; Sembiring, Sindy Boru; Yumardika, Deza; Renaldi, Muhammad Rizal; Pane, Herlin Novita; Tanjung, Fahrul Azmi; Siahaan, Nelly Christina; Mylano, Tri Adi; Nur, Putri Amriany
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7445

This study aimed to identify the factors influencing neck pain complaints among garment convection tailors in Medan City. A total of 44 tailors from a convection workshop on Jl. Denai were included as the study's population and sample, utilizing a total sampling technique. The research employed a cross-sectional analytical survey design with data analysis using the Chi-Square test. The findings from the bivariate analysis showed a significant association between neck pain complaints and three key factors: years of service (p=0.021), work duration (p=0.044), and work posture (p=0.000). Specifically, a higher percentage of severe neck pain was found in workers with fewer years of service and longer work durations (more than 8 hours a day). The analysis also revealed that age (p=0.717) and lighting (p=0.062) were not statistically significant factors. A subsequent multivariate analysis identified work posture and work duration as independent factors influencing neck pain, with work posture being the most dominant variable (p=0.000). The multivariate analysis for work posture had an odds ratio of 64.346, indicating a strong positive correlation with severe neck pain. However, a contradictory result for work duration in the multivariate analysis suggested a need for re-examination of its coding. The study concludes that workload, work duration, and working posture are the primary factors influencing neck pain complaints in convection tailors, with work posture being the most dominant. These findings highlight the importance of ergonomic interventions, proper posture, and regulated work hours to mitigate occupational health risks in this population.

Factors influencing the occurrence of neck pain complaints in garment convection tailors Siregar, Damayanti; Handoko, Ellya Keriahen; Setiawan, Deni; Sembiring, Sindy Boru; Yumardika, Deza; Renaldi, Muhammad Rizal; Pane, Herlin Novita; Tanjung, Fahrul Azmi; Siahaan, Nelly Christina; Mylano, Tri Adi; Nur, Putri Amriany
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7445

This study aimed to identify the factors influencing neck pain complaints among garment convection tailors in Medan City. A total of 44 tailors from a convection workshop on Jl. Denai were included as the study's population and sample, utilizing a total sampling technique. The research employed a cross-sectional analytical survey design with data analysis using the Chi-Square test. The findings from the bivariate analysis showed a significant association between neck pain complaints and three key factors: years of service (p=0.021), work duration (p=0.044), and work posture (p=0.000). Specifically, a higher percentage of severe neck pain was found in workers with fewer years of service and longer work durations (more than 8 hours a day). The analysis also revealed that age (p=0.717) and lighting (p=0.062) were not statistically significant factors. A subsequent multivariate analysis identified work posture and work duration as independent factors influencing neck pain, with work posture being the most dominant variable (p=0.000). The multivariate analysis for work posture had an odds ratio of 64.346, indicating a strong positive correlation with severe neck pain. However, a contradictory result for work duration in the multivariate analysis suggested a need for re-examination of its coding. The study concludes that workload, work duration, and working posture are the primary factors influencing neck pain complaints in convection tailors, with work posture being the most dominant. These findings highlight the importance of ergonomic interventions, proper posture, and regulated work hours to mitigate occupational health risks in this population.

The Role of Streptococcus mutans Virulence Proteins in the Pathogenesis of Endocarditis: Mechanisms of Action and Impact on Heart Infections, A Review Winato, Brigad Mahardika; Mylano, Tri Adi
Journal of Syiah Kuala Dentistry Society Vol 9, No 1 (2024): June 2024
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v9i1.40228

Background: Streptococcus mutans, known for causing dental caries, can also lead to endocarditis, a severe heart infection involving inflammation of the heart's inner lining and valves. This study focuses on the virulence proteins of Streptococcus mutans and their role in endocarditis pathogenesis. Objective: To investigate the mechanisms of action of Streptococcus mutans virulence proteins and their impact on the development of endocarditis. Methods: A comprehensive literature review focused on the virulence factors of Streptococcus mutans, such as Glucosyltransferases (Gtf), Adhesin P1 (Antigen I/II), Dextranase, and proteolytic enzymes. The role of these proteins in bacterial adhesion, biofilm formation, and tissue invasion was analyzed. Results: Glucosyltransferases facilitate biofilm formation by synthesizing sticky glucans from sucrose, protecting bacteria, and aiding the colonization of heart valves. Adhesin P1 enables bacterial attachment to host tissues, which is crucial for initial colonization. Dextranase modifies biofilm structure, enhancing stability and resistance. Proteolytic enzymes degrade host proteins, aiding bacterial invasion and causing tissue damage. Conclusion: Streptococcus mutans employ multiple virulence proteins to adhere to, colonize, and invade heart tissues, leading to endocarditis. Understanding these mechanisms is essential for developing preventive and therapeutic strategies against this severe infection.

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