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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) Buletin Kedokteran dan Kesehatan Prima
Yumardika, Deza
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Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Pengaruh Ekstrak Daun Sirsak (Annona Muricata L.) terhadap Fungsi Ginjal dan Histopatologi Tikus Putih Wistar Jantan Penderita Diabetes Melitus Usiana, Gusti Nyoman Bagus; Yumardika, Deza; Angkasa, Celvin
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.758

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak daun sirsak (Annona muricata L.) terhadap fungsi ginjal dan gambaran histopatologi ginjal pada tikus putih jantan galur Wistar yang menderita diabetes melitus. Induksi diabetes melitus dilakukan dengan pemberian aloksan dan tikus dibagi menjadi beberapa kelompok, yaitu kelompok kontrol, kelompok diabetes, dan kelompok perlakuan yang diberi ekstrak daun sirsak dengan dosis yang berbeda-beda. Fungsi ginjal dinilai melalui kadar nitrogen urea darah (BUN), kreatinin serum, dan asam urat. Pemeriksaan histopatologi ginjal dilakukan dengan pewarnaan hematoksilin dan eosin. Hasil penelitian menunjukkan bahwa pemberian ekstrak daun sirsak secara signifikan memperbaiki fungsi ginjal dengan menurunkan kadar BUN, kreatinin serum, dan asam urat. Selain itu, analisis histopatologi menunjukkan adanya penurunan kerusakan jaringan ginjal akibat diabetes. Temuan ini menunjukkan bahwa ekstrak daun sirsak memiliki potensi efek terapeutik dalam memperbaiki fungsi ginjal dan mengurangi kerusakan ginjal pada tikus diabetes.
Factors influencing the occurrence of neck pain complaints in garment convection tailors Siregar, Damayanti; Handoko, Ellya Keriahen; Setiawan, Deni; Sembiring, Sindy Boru; Yumardika, Deza; Renaldi, Muhammad Rizal; Pane, Herlin Novita; Tanjung, Fahrul Azmi; Siahaan, Nelly Christina; Mylano, Tri Adi; Nur, Putri Amriany
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7445

Abstract

This study aimed to identify the factors influencing neck pain complaints among garment convection tailors in Medan City. A total of 44 tailors from a convection workshop on Jl. Denai were included as the study's population and sample, utilizing a total sampling technique. The research employed a cross-sectional analytical survey design with data analysis using the Chi-Square test. The findings from the bivariate analysis showed a significant association between neck pain complaints and three key factors: years of service (p=0.021), work duration (p=0.044), and work posture (p=0.000). Specifically, a higher percentage of severe neck pain was found in workers with fewer years of service and longer work durations (more than 8 hours a day). The analysis also revealed that age (p=0.717) and lighting (p=0.062) were not statistically significant factors. A subsequent multivariate analysis identified work posture and work duration as independent factors influencing neck pain, with work posture being the most dominant variable (p=0.000). The multivariate analysis for work posture had an odds ratio of 64.346, indicating a strong positive correlation with severe neck pain. However, a contradictory result for work duration in the multivariate analysis suggested a need for re-examination of its coding. The study concludes that workload, work duration, and working posture are the primary factors influencing neck pain complaints in convection tailors, with work posture being the most dominant. These findings highlight the importance of ergonomic interventions, proper posture, and regulated work hours to mitigate occupational health risks in this population.
Gambaran Karakteristik Retinopati Diabetik di RS Mata Prima Vision Medan Kasdir, Kasdir; Yumardika, Deza; Suandy, Suandy
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i9.61672

Abstract

Retinopati diabetik (RD) merupakan komplikasi mikrovaskular utama diabetes melitus dan penyebab kebutaan yang dapat dicegah pada usia produktif, sehingga deteksi dini dan pemahaman karakteristik pasien sangat penting. Penelitian ini bertujuan untuk mendeskripsikan karakteristik pasien RD di RS Mata Prima Vision Medan berdasarkan jenis kelamin, usia, dan tingkat keparahan. Metode yang digunakan merupakan studi observasional cross-sectional yang dilakukan di RS Mata Prima Vision Medan dari Mei 2024 hingga Mei 2025. Data dikumpulkan dari rekam medis dari 36 pasien retinopati diabetik yang memenuhi kriteria inklusi.. Hasil penelitian menunjukkan sebanyak 69,4% pasien adalah perempuan dan 50,0% berusia 40-60 tahun. Sebagian besar (58,3%) sudah berada pada stadium proliferative diabetic retinopathy (PDR) saat diagnosis, dengan proporsi lebih tinggi pada perempuan (64,0%) dibandingkan laki-laki (45,5%). Temuan ini mengindikasikan keterlambatan deteksi dini, sehingga diperlukan program skrining rutin dan edukasi yang lebih agresif, khususnya untuk pasien perempuan dan kelompok usia >40 tahun, untuk mencegah progresivitas dan kebutaan.
Hubungan Derajat Miopia dengan Tekanan Intraokuler pada Pasien di RS Mata Prima Vision Medan Singh, Jak Mohan; Yumardika, Deza; Suandy , Suandy
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i9.61731

Abstract

Myopia is one of the most common refractive errors found in the community and has become a major cause of visual impairment and blindness worldwide. The degree of myopia may influence intraocular pressure (IOP), which is a major risk factor for glaucoma. This study aimed to determine the relationship between the degree of myopia and intraocular pressure among patients at Prima Vision Eye Hospital Medan. This research employed an analytical method with a cross-sectional design. The study sample consisted of 48 patients diagnosed with myopia who met the inclusion criteria. The degree of myopia was categorized based on refraction examination results, while IOP was measured using non-contact tonometry. Data were analyzed using the Chi-Square test. The results showed that most respondents were aged 21–30 years (39.6%) and the majority were female (58.3%). Most patients had moderate myopia (47.9%). Statistical analysis revealed a significant relationship between the degree of myopia and intraocular pressure (p < 0.05). In conclusion, there is a significant correlation between the degree of myopia and intraocular pressure among patients at Prima Vision Eye Hospital Medan. It is recommended that patients with high myopia undergo regular eye examinations for early detection of increased IOP and glaucoma risk.
Co-Authors Angkasa, Celvin DENI SETIAWAN Handoko, Ellya Keriahen kasdir, Kasdir Mylano, Tri Adi Nur, Putri Amriany Pane, Herlin Novita Renaldi, Muhammad Rizal Sembiring, Sindy Boru Siahaan, Nelly Christina Singh, Jak Mohan Siregar, Damayanti Suandy , Suandy Suandy, Suandy Tanjung, Fahrul Azmi Usiana, Gusti Nyoman Bagus