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Journal : CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL

Wilson’s Disease: A Review Amie Vidyani; Fauziah Diayu Retnaningtyas; Ulfa Kholili; Titong Sugihartono; Iswan Abbas Nusi; Poernomo Boedi Setiawan; Ummi Maimunah; Budi Widodo; Husin Thamrin; Muhammad Miftahussurur; Herry Purbayu
Current Internal Medicine Research and Practice Surabaya Journal Vol. 4 No. 1 (2023): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v4i1.36428

Abstract

Wilson’s disease is a disease that results from a genetic disorder that causes copper accumulation. Wilson’s disease has presented challenges for physicians during the last century, but it can be diagnosed and treated over time. Diagnosing Wilson’s disease is challenging for doctors because of its wide range of clinical manifestations and complexity. Studies that can help diagnose Wilson’s disease include a 24-hour copper urine examination and neurological tests, such as a CT scan or MRI, and liver function tests. There is also a scoring system to help medical personnel diagnose this disease. Correct diagnosis and adequate therapy can be provided, such as penicillamine, trientine, zinc, and, most rarely, liver transplantation. It is also necessary to monitor the side effects of treatment and its effectiveness of treatment. When receiving therapy, Wilson’s disease has a better prognosis than if it is not treated.
Diagnosis and Management of Patients with Radiation Colitis Made Bayu Agastia Rakateja; Budi Widodo
Current Internal Medicine Research and Practice Surabaya Journal Vol. 4 No. 1 (2023): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v4i1.42417

Abstract

Radiation colitis (Radiation Proctitis or Proctopathy) is a condition in which injury to the rectal mucosa is induced by radiation therapy to the pelvic organs. Radiation colitis is a condition that progresses and is becoming more common and dangerous—usually occurring 6 months to 5 years following regional radiation. This paper presented the diagnosis and management of patients with radiation colitis. There was a patient who had cervical cancer and was hospitalized every 2-3 months because of red blood chapters and weakness. She did chemotherapy and radiation for one year. The patient also received medical therapy, including rectal administration of sucralfate and oral sulfasalazine. Management of patients with radiation colitis is still a problem. There are no definite and consistent guidelines for the treatment of radiation colitis In this patient's case, medical therapy was recently carried out, including rectal administration of sucralfate and oral sulfasalazine. The patient was planning to undergo surgical therapy, but the patient and family refused. It is necessary to think about endoscopic therapy in patients. Argon plasma coagulation (APC) has become the most widely used first-line endoscopic therapy.