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EVALUASI PEMANTAUAN TERAPI OBAT PADA PASIEN ASCITES + CKD + HD ON TREATMENT DI RUMAH SAKIT “X” nuralang, nuralang; Ramatillah, Diana Laila
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 6, No 1 (2021)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v6i1.4628

Abstract

AbstrakCKD atau  disebut juga dengan gagal ginjal kronik merupakan kehilangan fungsi ginjal progresif, yang terjadi berbulanbulan sampai bertahun-tahun, yang di karakterisasi dengan perubahan struktur normal ginjal secara bertahap. Penyebab gagal ginjal kronik paling banyak di Indonesia adalah hipertensi (34 %), nefropati diabetika (27 %), dan glomerulopati primer (14 %). Selain itu penggunaan obat-obatan tertentu dapat menyebabkan gangguan terhadap fungsi ginjal, diantaranya adalah  penggunaan obat-obat antihipertensi, antibiotik dan AINS pada penderita pnyakit ginjal yang pada akhirnya berisiko tinggi mendapatkan Drug Related Problems (DRPs). Tujuan studi kasus ini adalah untuk mengetahu evaluasi dan mengidentifikasi DRPs pemantauan terapi obat pada pasien gagal ginjal kronik. Metode yang dilakukan secara univariat dengan cara analisa profil pengobatan pasien sesuai dengan DRPs. Dari hasil studi kasus diperoleh kesimpulan bahwa terapi pengobatan yang diterima oleh pasien, masih terdapat beberapa penggunaan obat yang tidak rasional, khususnya pada lama terapi pengobatan selain itu juga terdapat beberapa jenis obat yang dapat menimbulkan interkasi apabila digunakan secara bersamaan.  
Microencapsulation of Fermented Red Palm Oil with L. casei as Nutracetical Source Hertanti, Hertanti; Nuralang, Nuralang; Susanto, Nindita Clourisa Amaris; Tarigan, Indra Lasmana; Nelson, Nelson
Jurnal Rekayasa Kimia & Lingkungan Vol 17, No 2 (2022): Jurnal Rekayasa Kimia & Lingkungan (December, 2022)
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23955/rkl.v17i2.27110

Abstract

Red Palm Oil (RPO) is the result of refining from Crude Palm Oil (CPO) which still maintains a high level of phytonutrients that are beneficial for health. The benefits of RPO can be used as a nutraceutical source, because RPO acts as a provitamin A and vitamin E. The addition of Lactic Acid Bacteria (LAB) in a product functions as a probiotic with metabolite activity that can inhibit pathogenic microorganism thereby increasing the durability of a product. The addition of LAB to RPO is expected to increase the nutraceutical value by adding probiotic properties to RPO products. Microencapsulation technology can protect the bioactive content of essential oils against unwanted chemical interactions with other components and provide increased stability during processing. This research is expected to be able to provide information about the potential raw material of fermented RPO as a nutraceutical source by showing the profile of RPO before and after the fermentation process, chemical and physical properties of the microencapsulant. The microencapsulation technique used is the extrusion method. Fermentation of the bioactive compound ingredients in RPO using L. casei has a significant effect. RPO after fermentation using L. casei (Red-PalmZym) produces major compounds in the form of 9-Octadecenoic acid, methyl ester, (E)- Fermentation of RPO with L. casei increases the components of chemical compounds contained therein. The stability of the RPO microencapsulated before fermentation provided an effective protection against oxidative damage to the oil and proved that the microencapsulation process can reduce the level of damage to the oil.