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Mursal, Iin Lidia Putama
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN SHEET MASK BIOSELULOSA MENGANDUNG MINYAK ATSIRI BUNGA KENANGA (Cananga odorata) Farhamzah, Farhamzah; Yuniarsih, Nia; Mursal, Iin Lidia Putama; Anggraeni, Fera
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1224

Abstract

The use of antioxidants can be administered orally or topically. Antioxidants are known to be better if given topically in topical dosage forms such as sheet masks, so it is necessary to make masks from natural ingredients that have high antioxidant activity such as Cananga odorata because they contain benzyl benzoate which has anti-free radical properties. This study aims to prove the preparation of biocellulose essence sheet mask containing Cananga odorata has antioxidant activity with concentrations of F1, F2 and F3. Antioxidant testing using the DPPH method. Evaluation of biocellulose sheet mask preparations includes the mask sheet weight test and the mask sheet thickness test. Evaluation of essence preparations includes organoleptic, pH, viscosity, irritation, and hedonic tests. The positive phytochemical screening results contained alkaloids, flavonoids, tannins, and saponins. The results of testing the antioxidant activity of Cananga odorata obtained an IC50 value of 4.027 ppm. Evaluation of essence preparations obtained homogeneous, pH (5.01-6.43), viscosity (400-600 cPs), no irritation occurred in volunteers. Cananga odorata has antioxidant activity in the weak to moderate category, IC50 results for each formula F1 184.212 ppm, F2 150.175 ppm, and F3 72.448 ppm. Based on these results it can be concluded that Cananga odorata can be formulated as an essence with strong antioxidant potential with an IC50 value of 4.027 ppm.
PENGEMBANGAN DAN UJI AKSEPTABILITAS FORMULA “BELIWUH” PLESTER DEMAM HIDROGEL GUNA ULANG BERBAHAN TANAMAN BELIMBING WULUH (Averrhoa Bilimbi L.) Sugiharta, Sudrajat; Mudrikah, Siti; Mursal, Iin Lidia Putama; Rahma, Suci; Nisa, Shabrina Zahratun; Zahro, Putri Latifah Nur; Hermawan, Ghifari Hanif
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1522

Abstract

Fever is commonly managed using conventional oral medications, however, compresses remain a widely preferred adjunctive therapy. Most commercially available compresses are single-use, making them economically inefficient. Averrhoa bilimbi L. (bilimbi) possesses known antipyretic activity and contains bioactive compounds such as alkaloids, flavonoids, and saponins, which have potential as natural antipyretic agents. This study aimed to develop an optimal formulation based on varying concentrations of PVP K-30 and potassium chloride (KCl), and to evaluate the quality of bilimbi-based hydrogel and hydrogel plaster formulations that are reusable, stable, comfortable to use, and have minimal side effects. An experimental design was employed to prepare three hydrogel plaster formulations using different concentrations of PVP K-30 and KCl. The formulations were evaluated for organoleptic properties, homogeneity, adhesiveness, pH, gel fraction, swelling index, viscosity, thickness, moisture absorption, folding endurance, weight uniformity, and acceptability. All formulations met established quality standards for hydrogel and hydrogel plasters. The resulting plasters exhibited a solid gel consistency, green coloration, and a distinctive green tea scent, with safe pH values ranging from 4.2 to 6.5. The P4K2.5 formulation demonstrated the most stable viscosity (16,575.3 cP), while P4.5K3.5 was identified as the most optimal overall. P3.5K1 was most preferred in terms of color; P4K2.5 and P4.5K3.5 in aroma; and P3.5K1 and P4.5K3.5 in texture. After five hours of use, participants strongly favored P4K2.5 and P4.5K3.5. Notably, P4.5K3.5 also provided the highest cooling sensation after refrigeration and is recommended as a promising candidate for a reusable hydrogel plaster formulation for fever therapy.
PERAN AMILITE GCK-12H SEBAGAI SURFAKTAN PADA FORMULA SHAMPO: KAJIAN STABILITAS BUSA DAN EFEKTIVITAS PEMBERSIHAN Yuniarsih, Nia; Gunarti, Neni Sri; Mursal, Iin Lidia Putama; Angeline, Tiara Maharani; Abriyani, Ermi
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1543

Abstract

Shampoo functions to clean hair and scalp and is generally formulated using Sodium Lauryl Sulfate (SLS) surfactants, which are associated with irritation and unstable foam. Surfactant selection is therefore a critical factor in shampoo formulation, as it influences foam production, softness, hair moisture retention, environmental friendliness, and cleansing effectiveness. Amino acid–based surfactants such as Amilite GCK-12H offer advantages including low irritation potential, good foam stability, and biocompatibility. This study aimed to evaluate the effect of Amilite GCK-12H concentration on cleaning power and foam stability in shampoo formulations. The study was conducted by formulating shampoos and performing accelerated stability testing, including pH, viscosity, organoleptic properties, spreadability, homogeneity, foam stability, and cleaning effectiveness. Four formulations were prepared: F0 without Amilite GCK-12H, F1 containing 5%, F2 containing 10%, and F3 containing 15% Amilite GCK-12H. Organoleptic evaluation showed stable odor and homogeneity in all formulations, although color changes occurred in samples exposed to sunlight. pH testing indicated that all formulations remained within the acceptable range of 5.0–9.0, despite slight decreases under certain storage conditions. Viscosity increased at room temperature but decreased at elevated temperatures. Homogeneity and spreadability tests met standard requirements for shampoo preparations. Formulation F3 demonstrated the best performance in foam stability and cleaning effectiveness, achieving a cleaning efficiency of 62% on day 30. Overall, Amilite GCK-12H proved effective in producing a stable shampoo formulation with improved foam characteristics and cleansing performance. These findings support its potential application as a mild, high-performance surfactant for sustainable cosmetic shampoo development in future industrial formulations globally.
Co-Authors Abriyani, Ermi Angeline, Tiara Maharani Anggraeni, Fera Farhamzah Gunarti, Neni Sri Hermawan, Ghifari Hanif Nia Yuniarsih, Nia Nisa, Shabrina Zahratun Rahma, Suci siti mudrikah Sugiharta, Sudrajat Zahro, Putri Latifah Nur