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All Journal The International Journal of Accounting and Business Society Indonesian Journal of Biotechnology Prosiding Seminar Nasional Darmajaya Wistara: Jurnal Pendidikan Bahasa dan Sastra
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Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Social Sciences

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T-786c Polymorphism in nitric oxide synthase 3 gene and Nitrit Oxide Level of Diabetic Retinopathy in Javanese Population Welkriana, Putri Widelia; -, Sunarti; Hastuti, Pramudji
Indonesian Journal of Biotechnology Vol 16, No 2 (2011)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (43.035 KB)

Abstract

AbstractComplication of retinopathy in type 2 DM is caused of lower level of NO. Nitric oxide level is synthesizedfrom L-arginin in reaction that catalyze Nitric oxide synthase (NOS) 3. The T-786C mutation in NOS 3 genedecreases the expression of nitric oxide synthase (NOS) 3 so decreases NO synthesis. To investigate theassociation between T-786C polymorphism in NOS 3 gene with NO level of diabetic retinopathy patients. Thisstudy was a case control study, consist of 40 patient of type 2 diabetic with DR (case group) and 40 patient oftype 2 diabetic without DR (control group) of Javanese ethnic. The genotyping of T-786C polymorphism wasperformed by PCR-RLFP. Level of NO was measured by spectrophotometry. Chi square test and odd ratiowere used to analyze the association of the T-786C polymorphism in NOS 3 gene with DR. Differences ofNO level between TT and TC genotypes were analyzed using independent t test. The distribution of T-786Cpolymorphism in NOS 3 gene of DR subjects showed that frequency of TT genotype was 22.5% and TC genotypewas 77.5%. Non DR subjects showed the frequency of TT genotype was 50% and TC genotype was 50%, (p=0.011). Frequency of T allele in DR group was 61.25% and C allele was 38.75%, and frequency of T allele in nonDR group was 75% and C allele was 25%, (p= 0.62). Odd ratio of TC genotype was 3.444(CI; 95% : 0.964-3.735)and C allele was 1.898 (CI; 95% : 1.310-9.058). The NO level of TC genotype was 1.43+0.126 and TT genotypewas 11.27+5.87 (p=0.000). Level of NO between RD and non RD showed not different significantly (p=0.160)for retinopathy. The T-786C polymorphism of NOS 3 gene is risk factor for retinopathy in type 2 DiabetesMellitus. Individual with TC genotype of NOS 3 gene has lower level of NO than TT genotype.Keywords : Diabetic Retinopathy, Polymorphism, Nitric Oxide, Nitric Oxide Synthase.
APLIKASI PUPUK POPS PADA TANAMAN PADI: PENELITIAN DUA TAHUN Hasibuan, Ikhsan; -, Sunarti
Prosiding Seminar Nasional Darmajaya Vol 1 (2017): SEMNAS IIB DARMAJAYA
Publisher : Prosiding Seminar Nasional Darmajaya

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Pelepah sawit berpotensi sangat besar untuk dikembangkan menjadi pupuk organik. Setidaknya ada 3 kelebihan pelepah sawit dibanding bahan lainnya yaitu pertama, kita memiliki lahan perkebunan sawit yang sangat luas; kedua, pelepah sawit tersedia sepanjang tahun dengan harga murah atau bahkan gratis; dan  ketiga sudah ada teknologi untuk mencacah pelepah sawit yang keras yaitu mesin chopper. Dengan tiga pertimbangan diatas kami mengembangkan pupuk POPS atau pupuk organik pelepah sawit. Untuk mengevalusi seberapa efektif pupuk ini, kami telah melaksanakan penelitian selama dua tahun pada tanaman padi sawah dengan metode pertanian organik. Sebagai pembanding kami menggunakan bokashi pupuk kandang dan pupuk kimia. Tiga taraf dosis digunakan untuk melihat respon tanaman terhadap perbedaan tingkat hara yang diberikan. Hasil penelitian menunjukkan bahwa pada tahun pertama penelitian hasil padi dengan menggunakan pupuk pops lebih rendah dibandingkan dengan aplikasi pupuk kimia yaitu 5,16 dan 5,39 ton per hektar berturut-turut untuk pupuk pops dan kimia. Namun pada tahun kedua, hasil padi dengan pupuk pops meningkat signifikan sedangkan dengan pupuk kimia hasilnya menurun sehingga terjadi perubahan ranking dimana pupuk pops menjadi lebih tinggi hasilnya dibanding pupuk kimia yaitu 6,47 ton per hektar untuk pupuk pops sedangkan pupuk kimia hasilnya hanya 4,77 ton per hektar. Dari sini kami menyimpulkan bahwa aplikasi pupuk pops berdampak positif pada peningkatan produksi padi secara berkelanjutan dimana hasil tanaman padi akan meningkat seiring waktu. Kata kunci: pelepah sawit, pupuk organik, pertanian organik, padi
THE INFLUENCE OF PERCEIVED EASE OF USE, DISCOUNT, AND PERCEIVED USEFULNESS ON INTENTION TO USE GRAB APLICATION AND IT’s IMPACT ON PURCHASE DECISION OF GRAB SERVICES Ritonga, Nursakinah; Astuti, Endang Siti; -, Sunarti
The International Journal of Accounting and Business Society Vol 27, No 2 (2019): The International Journal of Accounting and Business Society
Publisher : Accounting Department,

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijabs.2019.27.2.3

Abstract

The purpose of this study is to explain and analyze the influence of Perceived Ease of Use, Discount, Perceived Usefulness  on Intention to Use the Grab application and its impact on Grab service purchasing decisions. This study uses a quantitative approach using explanatory research. The population of this study is undergraduate students in business administration study programs for 2017 and 2018 Faculty of Administrative Sciences, Universitas Brawijaya, Malang. with a total of 734 people. To determine the sample of the population, researchers used the Yakane formula to obtain the number of respondents as many as 90 people. The sampling technique of this study is non probability  sampling technique with the number of samples taken proportionally following the number of students in 2017 and 2018. The method of data collection used a questionnaire distributed to the respondent classes and calculated  using a Likert scale.Data analysis methods consist of test instruments, research requirements testing and hypothesis testing with path ananlysis by SPSS. The results of this study indicate that the Perceived Ease of Use, Discount, Perceived Usefulness has a positive and significant effect on the Intention to use Grab application. In addition the variable Perceived Ease of Use, Discount, Intention to Use Grab application also has a positive and significant influence on purchasing decisions. While the Perceived Usefulness variable has a positive but not significant effect on Purchasing Decisions.
Penggunaan Model Project Based Learning dalam Menulis Puisi Berorientasi Kearifan Lokal dan Dampaknya Terhadap Kemampuan Berpikir Kreatif Siswa Kelas X SMA Negeri 2 Padalarang -, Sunarti
Jurnal Pendidikan Bahasa dan Sastra Vol 2 No 1 (2021): Vol. 2 No. 1, Mei 2021
Publisher : Program Studi Magister Pendidikan Bahasa dan Sastra Indonesia, Program Pascasarjana, Universitas Pasundan Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/wistara.v2i1.2286

Abstract

Penelitian ini dimaksudkan untuk mengetahui bagaimana kemampuan peserta didik dalam menulis puisi bertema keindahan alam yang berorientasi kearifan lokal Situ Ciburuy dengan menggunakan model Project Based Learning (PBL) dan dampaknya terhadap kemampuan berpikir kreatif peserta didik. Populasi penelitian ini adalah seluruh peserta didik SMAN 2 Padalarang dengan sampel kelas X MIPA 4 (kelas eksperimen) dan kelas X MIPA 5 (kelas control). Metode penelitian yang digunakan metode campuran (mix method). Instrumen yang digunakan berupa lembar soal menulis puisi, lembar observasi, dan angket. Data penelitian dianalisis secara kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan antara kemampuan menulis puisi yang menggunakan model PBL dengan kelas yang menggunakan metode karya wisata. Hasil penelitian juga menunjukkan kemampuan berpikir kreatif peserta didik yang menggunakan model PBL lebih berkualitas, sehingga model PBL dapat dijadikan alternatif model dalam pembelajaran menulis puisi.
Co-Authors Endang Siti Astuti Ikhsan Hasibuan Pramudji Hastuti, Pramudji Putri Widelia Welkriana Ritonga, Nursakinah