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All Journal Jurnal Farmasi Sains dan Komunitas Jurnal Pengabdian UntukMu NegeRI JPSCR : Journal of Pharmaceutical Science and Clinical Research Borneo Journal of Pharmacy
Zulpadly, Muhammad Fiqri
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Religion Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Hematology Toxicities in Paclitaxel-Carboplatin Cancer Regiment Meitasari, Annisa Diyan; Ermawati, Dian Eka; Rohmani, Sholichah; Sasongko, Heru; Zulpadly, Muhammad Fiqri; Utami, Diyah Tri; Susanto, Nindita Clourisa Amaris; Untari, Meta Kartika; Darojati, Ulfa Afrinurfadhilah
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007064

Abstract

Chemotherapy is one of therapy for patients with cancer. Treatment carboplatin paclitaxel regimen is usually use for cervix, breast, and ovarium cancer. But the data of ADRs in hematology toxicity caused paclitaxel-carboplatin regiment is minimal, so it is required to do research. The aim of this research is can give information about the hematology toxicity, incident, severity, relationship between risk factor due incident of myelosuppression, and relationship between pre post chemotherapy due the myelosuppression. The severity ADRs use CTCAE 5.0. The ADRs were evaluated by severity, descriptive statistics, and some bivariate analysis. Anemia (66.46%) has a highest incident and followed by leukopenia (18.18%), neutropenia (13.22%), and thrombocytopenia (9.09%). Type of cancer associate with incident of anemia, leukopenia, and thrombocytopenia. The number of cycle chemotherapy use carboplatin paclitaxel regiments affects significant with the incidence of anemia. Patients who use paclitaxel-carboplatin as a regimen chemotherapy confirmed decrease in hematologic data such as hemoglobin, leukocyte, and thrombocyte.
Pendampingan Pembuatan Hand Sanitizer Aroma Minyak Atsiri Sebagai Penunjang Pembelajaran Luring Di SMP Muhammadiyah 1 Prambanan Kundarto, Wisnu; Ermawati, Dian Eka; Zulpadly, Muhammad Fiqri; Sasongko, Heru; Rohmani, Sholichah; Artanti, Anif Nur; Sahifah, Daswati Rofiatun
Jurnal Pengabdian UntukMu NegeRI Vol. 5 No. 2 (2021): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v5i2.3085

Abstract

The schools have been allowed for doing face-to-face learning process with many requirements.Making own hand sanitizer will help schools to keep applying health protocol beside washing hands. Essential oils have been trusted for a long time give a calm effect and reduce stres. This activity have purpose to assistance hand sanitizer production with essential oils fragrance at SMP Muhammadiyah 1 Prambanan Yogyakarta. Knowledge have been transfered by team followed with demo and training to produce hand sanitizer with lemongrass fragrance at first activity. Knowledge score was determined from pre-test and post test answer score from multiple choice questions about hand sanitizer. Follow up became the next activity to ensure school can make their own hand sanitizer independently. The result showed knowledge score was increased from 52,11 to 92,11. School also have been made hand sanitizer independently with another essential oil varians. This products were limited used for school. Communication between team and school still continues.
Evaluation of Antibiotic Planning in the UNS Hospital Pharmacy Installation in 2021 Zulpadly, Muhammad Fiqri; Syarofina, Nisa’
Borneo Journal of Pharmacy Vol. 6 No. 4 (2023): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v6i4.4944

Abstract

Planning is a drug selection activity in determining the type and amount of drug to increase efficiency, periodic and rational use of drugs, as well as obtaining an estimate of the amount of drug needed. Antibiotics are drugs that are often used and absorb many funds, so effective planning needs to be done so that inventory can be under control. This study aims to obtain a drug classification for antibiotics with the ABC analysis method to facilitate the control of antibiotic drugs in the Hospital Pharmacy Installation UNS. This research includes non-experimental research with descriptive analysis using quantitative and qualitative data. Quantitative data was obtained from prescriptions containing antibiotic drugs during 2021, and qualitative data regarding planning processes and systems procurement of drugs was obtained based on interviews with the Hospital Pharmacy Installation UNS warehouse coordinator. In this study, the results obtained were that of 100 drug items antibiotics, class A consists of three drug items (22.2%), class B consists of 10 drug items (22.47%), and class C consists of 57 drug items (55.33%). Class A has a planned budget proportion of IDR 413,106,692 (66.73%) of the total budget: IDR 619,100,298; Class B has a planned budget proportion of IDR 140,848,487 (22.75%); Class C has a planned budget proportion of IDR 65,145,119 (10.52%). Using the ABC method can simplify planning and procuring drugs and affect the proportion of the budget for drug procurement in hospitals.
Potential Fish Oil as Acute Hepatitis Candidate by Hepatoprotective Mechanism: A-review Sasongko, Heru; Zulpadly, Muhammad Fiqri; Farida, Yeni
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 8, No 2 (2023)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v8i2.68523

Abstract

Acute hepatitis is a health concern that emerged during the COVID-19 outbreak. Toxic drugs, infections, autoimmune diseases, and other causes may induce acute hepatitis, which is deadly. Acute hepatitis isn't treatable. Renewable natural products, such as fish, are used in complementary treatment. This paper mentions current preclinical and clinical studies of omega-3 fatty acids (N-3 FAs) for hepatoprotection. The mechanism of inhibition of oxidative stress and inflammation in the liver is the subject of discussion associated with its potential as a treatment for acute hepatitis. This review article on acute hepatitis treatment analyzed original articles, books, and other relevant material from the Web of Science, Scopus, and PubMed. The literature search was conducted in April-July 2022. The keywords explored during the literature investigation were "omega-3 or EPA or DHA or fish oil," "hepatoprotective," "acute hepatitis," "inflammatory", and "stress oxidative". The study's results show that N-3 FAs can protect against liver damage through inflammation and oxidative stress pathways. Enzyme parameters of liver damage, proinflammatory cytokines, and oxidative stress can be inhibited by the administration of fish oil and its derivatives. Even though not all clinical trial parameters are directly related to animal tests, the results of this study show that omega-3 fatty acids should be considered a treatment option for acute hepatitis.
Co-Authors Anif Nur Artanti, Anif Nur Darojati, Ulfa Afrinurfadhilah Daswati Daswati ERMAWATI, DIAN EKA Farida, Yeni Heru Sasongko Kundarto, Wisnu Meitasari, Annisa Diyan Sholichah Rohmani, Sholichah Susanto, Nindita Clourisa Amaris Syarofina, Nisa’ untari, meta kartika Utami, Diyah Tri