Article Per Year (5 Year)
p-Index From 2020 - 2025
1.745
P-Index
This Author published in this journals
All Journal Indonesian Journal of Cancer Chemoprevention Jurnal Farmasi Sains dan Komunitas Jurnal Pengabdian UntukMu NegeRI JCES (Journal of Character Education Society) JSFK (Jurnal Sains Farmasi & Klinis) JPSCR : Journal of Pharmaceutical Science and Clinical Research PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Jurnal Kefarmasian Indonesia
Sholichah Rohmani, Sholichah
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 10 Documents
Search

 1 
Uji Stabilitas dan Aktivitas Gel Handsanitizer Ekstrak Daun Kemangi Rohmani, Sholichah; Kuncoro, Muhammad A.A.
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 4, No 1 (2019)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v4i1.27212

Abstract

Daun kemangi memiliki potensi kuat yang beraktivitas untuk menghambat pertumbuhan bakteri S.aureus. Untuk meningkatkan keefektifitasan dalam pemanfaatan potensi ekstrak daun kemangi, maka dibuat dalam bentuk sediaan yang praktis dan mudah digunakan. Salah satu bentuk sediaan yang efektif untuk terapi topikal adalah handsanitizer gel. Faktor yang mempengaruhi kualitas sediaan gel salah satunya adalah penggunaan bahan tambahan seperti gelling agent, dimana pemilihan jenis dan konsentrasi gelling agent akan menentukan kestabilan gel yang terbentuk, sehingga penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi CMC Na sebagai gelling agent terhadap stabilitas fisik dari gel handsanitizer ekstrak daun kemangi sebagai antibakteri. Ekstrak daun kemangi diperoleh dengan metode maserasi menggunakan pelarut etanol 96%. Ekstrak yang dihasilkan diformulasikan dalam sediaan  gel dengan penambahan CMC Na 1%(F1), 2%(F2), 3%(F3). Setiap formula dilakukan pengujian stabilitas fisik meliputi uji organoleptis, uji homogenitas, uji daya sebar, uji daya lekat, uji pH, dan cycling test selama 6 siklus serta uji aktivitas antibakteri. Dari hasil penelitian diketahui bahwa perbedaan konsentrasi CMC Na sebagai gelling agent berpengaruh terhadap konsistensi, daya lekat, daya sebar, dan aktivitas antibakteri dari sediaan gel handsanitizer ekstrak daun kemangi, dimana peningkatan konsentrasi CMC Na maka konsistensi semakin meningkat, daya lekat semakin lama, daya sebar semakin kecil, dan aktifitas antibakterinya semakin menurun, namun perbedaan konsentrasi CMC Na tidak berpengaruh terhadap pH dan homogenitasnya. Gel handsanitizer ekstrak daun kemangi memiliki stabilitas yang baik sebelum maupun sesudah cycling test.
PENGEMBANGAN PRODUK TEH HERBAL BERBAHAN DASAR TOGA BERSAMA KWT BAGAS WARAS Susanto, Nindita Clourisa Amaris; Rohmani, Sholichah; Ermawati, Dian Eka; Sasongko, Heru; Zulpadly, M. Fiqri; Utami, Diyah Tri; Meitasari, Annisa Diyah; Darojati, Ulfa Afrinurfadhilah; Untari, Meta Kartika
JCES (Journal of Character Education Society) Vol 6, No 4 (2023): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jces.v6i4.16741

Abstract

Abstrak: Kelompok Wanita Tani (KWT) Bagas Waras merupakan kelompok produktif yang berfokus pada Tanaman Obat Keluarga (TOGA) dari pembibitan hingga pengolahan pasca panen. Kelompok Wanita Tani (KWT) Bagas Waras telah mengembangkan TOGA menjadi beberapa produk olahan makanan seperti keripik dan kue kering dan produksi dalam bentuk simplisia kering. KWT membutuhkan produk inovasi lain yang dapat mendukung dalam pengembangan pemnfaatan TOGA. Tim pengabdian memberikan transfer ilmu dalam pembuatan teh herbal untuk menjadi salah satu produk inovasi yang dapat dikembangkan oleh ibu-ibu di KWT Bagas Waras. Pelaksanaan pengabdian dilakukan dengan melibatkan ibu-ibu anggota KWT Bagas Waras sebanyak 25 orang melalui beberapa tahapan yaitu persiapan, pelatihan dan evaluasi. Kegiatan pengabdian kepada masyarakat ini diharapkan dapat mengenalkan teh herbal dengan campuran beberapa jenis TOGA dan dilakukan pengemasan dalam bentuk teh celup. Kegiatan pengabdian kepada masyarakat yaitu pelatihan pembuatan teh herbal telah terlaksana dengan baik. Kegiatan mendapatkan respon yang baik dari KWT Bagas Waras dan peserta antusias. Hasil kegiatan diperoleh 3 varian produk teh herbal dengan bahan dasar TOGA.Abstract: Bagas Waras Women Farmers Group (KWT) is a productive group that focuses on Family Medicinal Plants (TOGA) from nursery to post-harvest processing. Bagas Waras Women Farmers Group (KWT) has developed TOGA into several processed food products such as chips and pastries and production in the form of dry simplisia. KWT needs other innovative products that can support the development of TOGA utilization. The service team provided knowledge transfer in making herbal tea. The implementation of the service was carried out by involving 25 women members of KWT Bagas Waras through several stages, namely preparation, training and evaluation.. This community service activity is expected to introduce herbal tea with a mixture of several types of TOGA and packaging in the form of tea bags. Community service activities, namely training in making herbal tea, have been carried out well. The activity received a good response from KWT Bagas Waras and enthusiastic participants.
Pengaruh Variasi Konsentrasi Surfaktan Iselux Ultra Mild pada Formulasi Hydrating Facial Wash Potassium Azeloyl Diglycinate Rohmani, Sholichah; Ningrum, Sonia Karunia; Wardhani, Wening Dyah; Kundarto, Wisnu
Jurnal Kefarmasian Indonesia VOLUME 12, NOMOR 1, FEBRUARI 2022
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v0i0.4969

Abstract

Potassium Azeloyl Diglycinate is an innovative molecule that active as a skin hydrating, brightening agent, and treating skin hyperpigmentation. Facial Wash with foam stabilizing agents called surfactants is a facial cleansing soap that used daily to clean dirt and oil on the face. Iselux ultra mild surfactant as a mild surfactant has a low irritation profile, stable to pH and has a soft and abundant foam. This research is an experimental study. Formulating a good Hydrating Facial Wash Potassium azeloyl diglycinate with the addition of of Iselux ultra mild surfactants in various concentration, according to physical and chemical characteristics as well as a facial wash hydration test. Researchers used various concentration of 28: 30: 32% Iselux Ultra Mild for 3 types of formulas. The test results were analyzed by one way ANOVA. The results of testing the characteristics of physical and chemical properties including organoleptic tests, homogeneity, spreadability, foam height, viscosity, and pH as well as hydration evaluation showed that the facial wash was not change during storage for 12 days using the cycling test method. Formula 3 with the highest surfactant concentration met the best qualification on the parameters compared to Formula 1 and Formula 2. The hydration activity test based on the results of the pre and post test showed that the Facial Wash Potassium azeloyl diglycinate had moisturizing activity on the face.
Formulation and Activity of Sunscreen Cream from Ethanol Extract of Calendula officinalis L Flowers Rohmani, Sholichah; Mar’atushsholihah, Luthfia; Darojati, Ulfa Afrinurfadhillah; Meitasari, Annisa Diyan; Susanto, Bela Novita Amaris
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 1 (2024): J Sains Farm Klin 11(1), April 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.1.48-57.2024

Abstract

Sunscreen made of natural ingredients is an alternative to protect the skin from excess UV radiation and a substitute for chemical products that have side effects. It was reported that Calendula officinalis L. has flavonoid and saponin metabolite compounds which function as photoprotective agents. This research aims to formulate sunscreen cream and examine the effect of variations in Calendula officinalis L flower extract (5%;7%;10% w/v) on physicochemical properties, stability, and values of the Sun Protecting Factor (SPF) in vitro using UV-Vis spectrophotometry and in vivo using wistar line rat test animals to see the time of formation of Minimum Erythema Dose (MED). It has been proven that variations in the concentration of Calendula officinalis L. extract affected the physicochemical properties, such as pH value, viscosity, spreadability, and adhesion strength. However, the overall results of the physicochemical properties still met the requirements. Variations in extract concentration affected the SPF value. In vitro SPF test showed the minimum protection category for F1, extra protection for F2, maximum protection for F3, and no protection for F0. Meanwhile, the in vivo SPF test showed the minimal protection category for F1, medium protection for F2, extra protection for F3, and no protection for F0.
Hydrating serum made of potassium azeloyl diglycinate with CMC-Na variations as a gelling agent on physical-chemical and safety tests Rohmani, Sholichah; Aditya, Shafira Nur; Husna, Hanna Miftahul; Ermawati, Dian Eka; Utami, Diyah Tri
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1257

Abstract

Potassium azeloyl diglycinate is an ingredient for moisturizing the skin. In this research, potassium-azeloyl-diglycinate was formulated into a gel-based hydrating serum. A good serum gel can be identified by its physicochemical properties and stability, which are determined by the composition of the ingredients used, one of which is CMC-Na, which is used as a gelling agent. The aim of this research was to test the effect of CMC-Na concentrations (1%, 1.25%, and 1.5%) on the physicochemical stability of serum and to find a formulation with the best stability by testing the water content and safety. The evaluation results show that increasing the concentration of CMC-Na has an impact on increasing viscosity, pH, and adhesion, thereby providing a different gel consistency in each formula and reducing its spreadability. The best formulation is Formula-2, which is then tested for water content on respondents. The research results show that this formula has the ability to hydrate the skin, as seen from an increase in oil content of 8.39% and an increase in water content of 8.86%. Initial acute dermal toxicity test results show that the serum is safe to use on the skin and does not cause side effects or toxicity reactions.
Hematology Toxicities in Paclitaxel-Carboplatin Cancer Regiment Meitasari, Annisa Diyan; Ermawati, Dian Eka; Rohmani, Sholichah; Sasongko, Heru; Zulpadly, Muhammad Fiqri; Utami, Diyah Tri; Susanto, Nindita Clourisa Amaris; Untari, Meta Kartika; Darojati, Ulfa Afrinurfadhilah
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007064

Abstract

Chemotherapy is one of therapy for patients with cancer. Treatment carboplatin paclitaxel regimen is usually use for cervix, breast, and ovarium cancer. But the data of ADRs in hematology toxicity caused paclitaxel-carboplatin regiment is minimal, so it is required to do research. The aim of this research is can give information about the hematology toxicity, incident, severity, relationship between risk factor due incident of myelosuppression, and relationship between pre post chemotherapy due the myelosuppression. The severity ADRs use CTCAE 5.0. The ADRs were evaluated by severity, descriptive statistics, and some bivariate analysis. Anemia (66.46%) has a highest incident and followed by leukopenia (18.18%), neutropenia (13.22%), and thrombocytopenia (9.09%). Type of cancer associate with incident of anemia, leukopenia, and thrombocytopenia. The number of cycle chemotherapy use carboplatin paclitaxel regiments affects significant with the incidence of anemia. Patients who use paclitaxel-carboplatin as a regimen chemotherapy confirmed decrease in hematologic data such as hemoglobin, leukocyte, and thrombocyte.
Pelatihan Pembuatan Lulur Tradisional Berbahan Dasar TOGA di Kelompok Wanita Tani (KWT) Bagas Waras Boyolali: Training on Making Traditional Scrubs Based on TOGA at KWT Bagas Waras Boyolali Darojati, Ulfa Afrinurfadhilah; Rohmani, Sholichah; Sasongko, Heru; Susanto, Nindita Clourisa Amaris; Zulpadly, M. Fiqri; Utami, Diyah Tri; Meitasari, Annisa Diyan; Untari, Meta Kartika; Ermawati, Dian Eka; Artanti, Anif Nur
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 9 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i9.8562

Abstract

The Bagas Waras Women's Farmers Group (KWT) is one of the women's groups that cultivates a lot of TOGA in Banyuanyar Village, Boyolali. Their seriousness in cultivating TOGA is proven by the establishment of Omah TOGA, which has become an educational tourism destination. KWT members also have high enthusiasm for developing TOGA's potential and have produced many processed food products from TOGA. KWT Bagas Waras needs innovations in TOGA products, namely traditional cosmetic products. The service team provides scientific insight through training on developing traditional cosmetic products, namely body scrubs made from various types of TOGA. This activity involves 40 KWT members who will participate in a series of stages: preparation, training, practice, and evaluation. This training activity can increase the scientific insight of KWT members and help them develop traditional body scrubs made from TOGA and good packaging methods. This training has gone well, with all participants very enthusiastically listening to material related to traditional cosmetics and demonstrating how to make body scrubs. The results obtained are traditional body scrubs with various variants originating from TOGA.
Pendampingan Pembuatan Hand Sanitizer Aroma Minyak Atsiri Sebagai Penunjang Pembelajaran Luring Di SMP Muhammadiyah 1 Prambanan Kundarto, Wisnu; Ermawati, Dian Eka; Zulpadly, Muhammad Fiqri; Sasongko, Heru; Rohmani, Sholichah; Artanti, Anif Nur; Sahifah, Daswati Rofiatun
Jurnal Pengabdian UntukMu NegeRI Vol. 5 No. 2 (2021): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v5i2.3085

Abstract

The schools have been allowed for doing face-to-face learning process with many requirements.Making own hand sanitizer will help schools to keep applying health protocol beside washing hands. Essential oils have been trusted for a long time give a calm effect and reduce stres. This activity have purpose to assistance hand sanitizer production with essential oils fragrance at SMP Muhammadiyah 1 Prambanan Yogyakarta. Knowledge have been transfered by team followed with demo and training to produce hand sanitizer with lemongrass fragrance at first activity. Knowledge score was determined from pre-test and post test answer score from multiple choice questions about hand sanitizer. Follow up became the next activity to ensure school can make their own hand sanitizer independently. The result showed knowledge score was increased from 52,11 to 92,11. School also have been made hand sanitizer independently with another essential oil varians. This products were limited used for school. Communication between team and school still continues.
Physicochemical Characterization, Cytotoxic Activity, and Caspase-9 Expression of Nanogold-Parijoto (Medinilla Speciosa Reinw .Ex, Bl ) in Hela Cell Lines Artanti, Anif Nur; Rohmani, Sholichah; Prihapsara, Fea; Utami, Diyah Tri; Amaris Susanto, Nindita Clourisa; Zulphadly, M.Fiqri; Meitasari, Annisa Diyan; Darojati, Ulfa Afrinurfadhilah; Untari, Meta Kartika; Sasongko, Heru; Ermawati, Dian Eka
Indonesian Journal of Cancer Chemoprevention Vol 15, No 3 (2024)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev15iss3pp175-185

Abstract

Parijoto (Medinilla speciosa, Reinw. ex. Bl.), a tropical plant native to Southeast Asia, contains flavonoids, tannins, and saponins, which have the potential as an anticancer. Gold nanoparticle-based drug formulations are applied to increase the anticancer effectiveness of herbal medicines. The compounds in the stalk of parijoto have the potential to be bioreductor in the biosynthesis of gold nanoparticles. This study aims to determine the physicochemical characterization, cytotoxic activity, and expression of protein caspase-9 after treatment with nanogold parijoto (AuNPs-PR) on HeLa cell. The nanogold biosynthesis process was done by reacting 1 mM HAuCl4 with parijoto aqueous extract (EP). Physicochemical characterization measure of particle size, Polydisperse Index (PdI), and zeta potential of AuNPs-PR was carried out using a particle size analyzer. The cytotoxic effect and viability cell of AuNPs- PR were carried out using the MTT assay. The expression of caspase-9 was observed by immunocytochemistry assay. Physicochemical characterization of AuNPs-PR shows that the particle size value is 160.8 nm with PdI and zeta potential values of 0.430 and -4.56 mV respectively. In the MTT assay, both AuNPs-PR and EP demonstrated a reduction in the viability of Hela cells after 24 h in a dose-dependent manner, yielding IC50 values of 3.28 μg/mL and 19.22 μg/mL, respectively. AuNPs-PR and EP showed low cytotoxic activity against Vero normal cells, with IC50 values of over 500 μM. Further, the immunocytochemistry assay indicated that there was upregulation of caspase-9 by their expression. These results indicate that AuNPs-PR could effectively induce apoptosis in HeLa cells by upregulating caspase-9.Keywords: caspase-9, HeLa cells, MTT, nanogold, parijoto.
Cytotoxicity Effect of Self-Nanoemulsifying Drug Delivery System from Chloroform Extract of Bay Leaf (Syzygium Polyanthum (Wight) Walp.) with Oleic Acid as a Carrier Artanti, Anif Nur; Prihapsara, Fea; Rohmani, Sholichah
Indonesian Journal of Cancer Chemoprevention Vol 13, No 2 (2022)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev13iss2pp94-103

Abstract

Bay leaves are used as food flavoring and also have medicinal properties. They may have cytotoxic effects derived from natural ingredients. The low efficacy of the therapy with an adequate dose preparation of the plant extract is due to its low solubility and oral bioavailability that is less than the maximum. Hence, this study aimed to improve the solubility and oral bioavailability of the extract mainly for the chloroform extract of leaves that are not soluble in water by preparing a self-nanoemulsifying drug delivery system (SNEDDS). Then, the potential cytotoxic effects of the SNEDDS of bay leaves were determined by calculating the value of IC50 on the T47D cell line. The cytotoxic effect of the SNEDDS of bay leaves was determined using an MTT assay, and the findings were read using an ELISA reader. Data analysis is calculated via linear regression methods by using Microsoft Excel software. The results showed that the SNEDDS of bay leaves performed cytotoxic effects on the T47D cell line with IC50 138 μg/mL. The results showed that the optimal composition formula SNEDDS, namely, Tween 20:PG:oleic acid = 2.25:2.25:0.5 in 5 mL SNEDDS preparation, which had a value of transmittance of 83.81% with emulsification time was less than 5 min; the average droplet size was 165.5 nm, and the zeta potential was −0.4 mV. The data analysis showed that the cytotoxicity effect of the SNEDDS of bay leaves is included in the moderate cytotoxic category.Keywords: Bay leaf, optimization, nanoemulsi, cytotoxicity.
Co-Authors Aditya, Shafira Nur Amaris Susanto, Nindita Clourisa Anif Nur Artanti, Anif Nur Darojati, Ulfa Afrinurfadhilah Darojati, Ulfa Afrinurfadhillah Daswati Daswati ERMAWATI, DIAN EKA Fea Prihapsara, Fea Heru Sasongko Husna, Hanna Miftahul Kuncoro, Muhammad A.A. Kundarto, Wisnu Mar’atushsholihah, Luthfia Meitasari, Annisa Diyah Meitasari, Annisa Diyan Ningrum, Sonia Karunia Susanto, Bela Novita Amaris Susanto, Nindita Clourisa Amaris untari, meta kartika Utami, Diyah Tri Wardhani, Wening Dyah Zulpadly, M. Fiqri Zulpadly, Muhammad Fiqri Zulphadly, M.Fiqri