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Skrining Fitokimia & Aktivitas Antibakteri Ekstrak Bunga Telang (Clitoria ternatea L.) terhadap Bakteri Staphylococcus epidermidis Sesilia, Riana; Priamsari, Margareta Retno; Akbar, Nanda Dwi
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p232-239

Abstract

Telang flowers contain secondary metabolite compounds that have benefits as antibacterial or antiseptic compounds including flavonoids, tannins, alkaloids and saponins. This research was an experimental research. Telang flower extract was obtained using 70% ethanol solvent by remaceration method then it tested like phytochemical content. Antibacterial activity testing with variaty concentrations media MHA (Mueller Hinton Agar) 15, 30, 45, 60, and 75% against Staphylococcus epidermidis. The positive control was Klindamycin. The obtained data were analyzed by Statistical Package for the Social Sciences (SPSS). The results shown that telang flower extract with concentrations 15, 30, 45, 60 and 75% had an average inhibition zone activity against Staphylococcus epidermidis were respectively 4.45 (15%); 4.63 (30%); 4.35 (45%); 5.47 (65%); and 7.02 mm (75%). The SPSS results show that the p value is <0.05 at the 95% confidence level, which indicates that there is a significant difference in antibacterial activity between butterfly pea flower extracts between concentrations of 15, 30, 45, 60, and 75%. Post hoc tests using LSD showed that there was a difference in antibacterial activity between concentrations of 75% and concentrations of 15, 30, 45, and 60%, but there was no difference in antibacterial activity between concentrations of 15, 30, 45, and 60%.Minimal inhibitor concentration of telang flower extract was obtained at 15%
FORMULASI DAN EVALUASI SEDIAAN SAMPO KOMBINASI EKSTRAK BONGGOL PISANG KEPOK (Musa x paradisiaca L.) dan MINYAK KELAPA (Virgin Coconut Oil) Akbar, Nanda Dwi; Cahyaningrum, Nineeteen Yuliya; Setiyaningsih, Wahyu; Solichah, Ayu Ina; Christina, Odilia Dea
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p176-187

Abstract

Shampoo is a hair care product that is used to clean the hair and scalp.Shampoo containing natural ingredients can be an alternative for healthy scalp and hair.The saponin content in the kepok banana hump (Musa x paradisiaca L.) can function as a foamer and a combination of coconut oil (Virgin coconut oil) as a moisturizer (emollient).This research aims to formulate and evaluate a shampoo preparation containing banana weevil extract (Musa x paradisiaca L.) and coconut oil (Virgin coconut oil) in the shampoo preparation. This research is an experimental research. In this research, the formulation of kepok banana weevil extract (Musa x paradisiaca L.) 4%, 8% and 12% and coconut oil (Virgin coconut oil) concentrations of 10%, 12% and 15% were carried out. Extract yield was carried out using the maceration method using 96% ethanol solvent with a ratio of 1: 7.5. Evaluation of the physical properties of shampoo includes organoleptic observations, pH determination, specific gravity measurement, foam height measurement, viscosity and homogeneity testing.Data analysis was carried out using SPSS. Based on research on kepok banana weevil extract (Musa x paradisiaca L.)a thick, reddish brown colored extract was obtained, with a distinctive slightly sweet aroma with a yield of 11.4445% from 400 grams of dried banana weevil. The results of the phytochemical screening of the thick extract of banana weevils were positive for containing saponin compounds. The test results for shampoo preparations F1, F2 and F3 have a cream to brownish cream color, a liquid texture and a coconut banana smell, homogeneous preparations, pH range 6.72 – 8.23; has a foam height of 1.8 – 2.3 cm; viscosity 216 – 250 dPas and specific gravity 0.9569 – 1.0272 g/mL. The results of analysis using One Way ANOVA showed a p value <0.05 in foam height, pH value and viscosity for the three formulas, there were significant differences.This research shows that the addition of banana weevil extract (Musa x paradisiaca L.) and coconut oil (Virgin coconut oil) affects the characteristics of the shampoo preparation.
Optimasi Formulasi Nanopartikel Gel Ekstrak Etanol Kayu Secang (Caesalpinia Sappan L.) Sebagai Antibakteri Terhadap Propionibacterium Acnes: Optimasi Formulasi Nanopartikel Gel Ekstrak Etanol Kayu Secang (Caesalpinia Sappan L.) Sebagai Antibakteri Terhadap Propionibacterium Acnes Maharani, Zahra Febriana; Akbar, Nanda Dwi; Priamsari, Margareta Retno
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 5 No 1 (2025): April - September
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v5i1.80

Abstract

Nanoparticle gel is a colloid consisting of nanometer-sized particles made from cosmetic active ingredients or other materials that are evenly distributed in a gel matrix. The purpose of this study was to determine the antibacterial activity of nanoparticle gel preparations of sappanwood extract against Propionibacterium acnes. The sappanwood extract was extracted by remaceration 70% ethanol then the extract was tested for antibacterial activity at concentrations of 20, 40, 60, and 80% using Nutrient Agar media against P. acnes. The results showed that the minimum inhibitory concentration of sappanwood extract appeared at a concentration of 20%. Spreadability and adhesiveness were 5.90 ± 0.06 and 14.96 ± 0.01, respectively. The results of the statistical analysis test with one sample t-test showed a p value> 0.05 so that the response of spreadability and adhesiveness between predictions was not significantly different from the actual. The optimal formula of sappanwood extract gel nanoparticles has moderate antibacterial activity against P. acnes.
Relationship Between Educational Level and Knowledge in Self-Medication of Diarrhea Disease Disease in Children Sari, Ferika Indra; Toyo, Eleonora Maryeta; Munawaroh, Siti; Akbar, Nanda Dwi
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3045

Abstract

In Indonesia, diarrhea is the second killer of toddlers after ISPA and 10,000 toddlers die from diarrhea every year. Proportion of diarrhea cases in Central Java in 2014 was 79.8%. The main options for seeking recovery from an illness include seeking treatment at a health service center or treating yourself. increasing knowledge about diarrhea, it is necessary to provide health education. The purpose of this study was to determine the relationship between the level of education with the level of knowledge of self-medication of diarrhea in children as parents in Bae District, Kudus Regency. Method: The purpose of research was to decide the relationship among the level of education and the level of knowledge of diarrhea self-medication in children as parents in Bae District, Kudus Regency. The research was called a quantitative research by a cross sectional approach. The population were all people in Bae District, Kudus Regency. The design of this research was quantitative analysis through a proportional sampling technique. The instrument is applied a questionnaire on a sample of 400 respondents in the community in Bae sub-district. The data analysis used in this study begins by using a validity test to measure whether a questionnaire is valid or not; reliability test to measure whether a questionnaire is consistent or stable over time. Furthermore, the One Sample Kolmogorov Smirnov test was carried out to see that the data was normally distributed and the Spearman rank test to determine the relationship or influence between two ordinal scale variables. Results and Conclusions: The results showed a significant relationship between education level and parental knowledge in self-medication for diarrheal disease in children with a correlation coefficient of 0.928, so it is included in the very strong category and the results are significant.
EDUKASI PEMANFAATAN TOGA DENGAN TOOLS SISTEM INFORMASI OBAL UNTUK SISWA SMK ASTA MITRA GROBOGAN Purwanjani, Wahyu; Septiarini, Anita Dwi; Suwarni, Sri; Gloria, Fransisca; Akbar, Nanda Dwi; Leki, Karol Giovani Battista
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 12 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Desember 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i12.2078

Abstract

This community service activity aims to improve the knowledge and skills of students at SMK Asta Mitra Grobogan in using Family Medicinal Plants (TOGA). The method used is an interactive educational approach, supported by the Natural Medicine Information System (Si-Obal). The activity included lectures, discussions, demonstrations on how to make herbal remedies, educational quizzes, and TOGA planting practices in the school environment. The results of the activity showed that students gained a better understanding of the types of medicinal plants, their benefits, and how to use them to safely treat minor health complaints. The use of Si-Obal as a digital medium was deemed effective and well-received by the students. It is hoped that this activity will contribute to improving health literacy, fostering a caring attitude towards the environment, and encouraging the sustainable use
Socialization of Making Cookies Containing Moringa Leaf Extract (Moringa oleifera L.) to Help Prevent Stunting Indrasari, Ferika; Akbar, Nanda Dwi; Leki, Karol Giovani Batista; Shifa, Ayu Atsna
Jurnal Abmas Negeri (JAGRI) Vol. 6 No. 2 (2025): Volume 6 Nomor 2 Desember 2025
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jagri.v6i2.1541

Abstract

The stunting rate among toddlers in Semarang City is 2,73%, consisting of 0,26% very short toddlers and 2,47% short toddlers. Although this prevalence is relatively low, continuous prevention and management efforts are still required to further reduce stunting cases. One local food ingredient with high nutritional potential is Moringa leaves (Moringa oleifera L.), which are rich in protein, vitamins, and minerals. Moringa leaves can be processed into various food products, including cookies. Cookies are a popular snack consumed by all age groups and have high energy content, making them suitable as complementary foods for toddlers. This community service activity aimed to increase public knowledge regarding the utilization of moringa leaf cookies as a stunting prevention strategy. The activity was conducted under the theme “Socialization of Making Cookies from Moringa Leaf Extract (Moringa oleifera L.) to Help Prevent Stunting.” A total of 50 PKK mothers participated from Bulu Lor Village, North Semarang, who participated in the activity. The intervention consisted of a 30-minute educational session using visual media, including pictures and PowerPoint presentations. Participants completed pre-test and post-test questionnaires that met validity and reliability standards. Data were analyzed univariately. The results showed that cookies with small amounts of moringa leaf powder were acceptable in taste and not bitter. Knowledge levels increased across all cognitive domains. Statistical analysis using a t-test indicated a significant difference between pre-test and post-test scores (p-value = 0,003). In conclusion, the activity effectively improved participants’ knowledge of using moringa leaf cookies to prevent stunting in toddlers.
Formulation of Spinach Leaf Extract (Amaranthus tricolor L.) Shampoo and Antifungal Activity Test Against Pityrosporum ovale Priamsari, Margareta Retno; Pinto, Marcia Angelica Vidigal Loi; Akbar, Nanda Dwi
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol. 22 No. 2 (2025): Jurnal Ilmu Farmasi dan Farmasi Klinis
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v22i2.14276

Abstract

Red spinach leaves contain flavonoid, tannin, alkaloid, saponin and terpenoid that have potential as antifungal compounds. This research is  experimental. The purpose of this reserach is is to find out extract red spinach leaves can inhibit the growth of Pityrosporum ovale and to find out that red spinach leaf extract can be formulated in shampoo. Extraction was carried out using the remaceration method with 70% ethanol solvent and then tested for phytochemical content. Antifungal activity testing of red spinach leaf extract using concentrations of 15; 30; 45; 60 and 75% using the well method with PDA media incubated at 37 for 3x24 hours. The results showed the average inhibition zone activity against Pityrosporum ovale at a concentration of 75% of 19.17 mm statistically showed a significant difference. Formulation of shampoo preparations was carried out on red spinach leaf extract at a concentration of 15% with variations in the formula of Cocamide DEA and CMC-Na. The physical characteristics of the shampoo preparation include organoleeptic test, homogeneity, pH, viscosity, adhesion, spreadability and foam height. The results of testing the antifungal activity of shampoo preparations in formula 1 (17.5 mm); formula 2 (17.83 mm); and formula 3 (16.83 mm), based on statistical tests of antifungal shampoo preparations with a p-value (> 0.05) variations in the concentration of Cocamide DEA and CMC-Na have no significant effect on antifungal activity.