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All Journal Indonesian Journal of Chemistry Pharmaceutical And Biomedical Sciences Journal (PBSJ) JPM-AKA
Prihadi, Anton Restu
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Medicine & Pharmacology Public Health Social Sciences

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Chemical Composition, Phytochemical Screening and Antioxidant Activity of Acmella uliginosa (Sw.) Cass Leaves Askal Maimulyanti; Anton Restu Prihadi; Iwan Safrudin
Indonesian Journal of Chemistry Vol 16, No 2 (2016)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.761 KB) | DOI: 10.22146/ijc.21160

Abstract

Acmella uliginosa (Sw.) Cass is widely used in traditional medicine and used in the treatment of many diseases. Extraction of component in leaves of Acmella uliginosa used methanol, ethyl acetate and n-hexane solvent. The percentage yield of extract from the leaves in methanol, ethyl acetate and n-hexane were 6.50, 0.49, and 0.66, respectively. Analysis of component in various extracts of Acmella uliginosa (Sw.) Cass leaves used Gas Chromatography-Mass Spectrometry (GC-MS). The various classes of phytochemicals were identified from fractions of methanolic leaves extract by GC-MS. Qualitative analysis of phytochemical constituents in methanol, ethyl acetate and n-hexane extract were tannins, flavonoids, saponin, alkaloid and steroid. Antioxidant activity of Acmella uliginosa leaves from Indonesia was carried out by using 1,1,diphenyl-2-picryl-hydrazine (DPPH) free radical scavenging assay. The IC50 of three extract was calculated. A comparative study determined that Acmella uliginosa in ethyl acetate extract showed the highest antioxidant potential (IC50 = 28.09 µg/mL) compared to methanol extract (IC50 = 44.31 µg/mL) and n-hexane extract (181.23 µg/mL) against DPPH free radicals.
Optimasi Proses Produksi Tahu Bandung dan Penerapan Industri 4.0 Di IKM Tahu Tansa Bogor Prihadi, Anton Restu; Maimulyanti, Askal; Styani, Erna; Mualim, Ahmad Dzaky; Puspita, Fitria; Putri, Fajar Amelia Rachmawati
Jurnal Pengabdian Masyarakat AKA Vol 4, No 2 (2024): Desember 2024
Publisher : Politeknik AKA Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55075/jpm-aka.v4i2.254

Abstract

IKM Tahu Tansa merupakan salah satu IKM di Kota Bogor yang memproduksi Tahu Bandung. Seiring dengan perkembangan waktu dan peningkatan produksi, IKM mengalami beberapa permasalahan seperti konsistensi kualitas organoleptik tahu yang disebabkan oleh suhu pemasakan dan penambahan garam yang tidak konsisten selain itu keterbatasan alat pada proses penyaringan kedelai. Pada akhirnya, hal ini dapat menimbulkan resiko penurunan kualitas dan kuantitas produksi tahu dan berpotensi meningkatkan biaya produksi yang berdampak pada lonjakan harga jual tahu. Berdasarkan permasalahan tersebut, tim PkM Politeknik AKA Bogor bermaksud untuk memberikan alternatif solusi penyelesaian  permasalahan yang dihadapi yaitu berupa pelatihan metode pengawasan suhu pemasakan agar optimum menggunakan teknologi arduino. Aplikasi ini akan memudahkan pekerja untuk memantau suhu sebenarnya di dalam kuali masak. Proses pemasakan yang optimum akan menyebabkan matinya seluruh bakteri patogen yang terdapat pada adonan tahu. Efektivitas proses pemasakan ini akan dipantau melalui analisis mikrobiologi. Sedangkan konsistensi penambahan garam pada adonan tahu  akan dipantau menggunakan titrimetri metode Mohr. Setelah diuji mutunya terkait kadar garam dan kadar mikroba dapat disimpulkan bahwa tahu bandung yang diproduksi IKM memiliki kualitas yang konsisten dan bebas dari bakter E.coli 
Optimization Parameters of Natural Deep Eutectic Solvent Based on Choline Chloride and Fructose for Extraction of Polyphenol from Jotang (Spilanthes acmella) Stem Putri, Fajar Amelia Rachmawati; Maimulyanti, Askal; Nurhidayati, Isna; Mellisani, Bella; Widarsih, R. Wiwi; Puspita, Fitria; Prihadi, Anton Restu
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 1 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i1.39583

Abstract

Natural deep eutectic solvents (NADES) have become popular as an environmentally benign alternative to conventional solvents for extracting natural compounds. In this current research, choline chloride was employed as a hydrogen bond acceptor (HBA) and was mixed with fructose which had the role of a hydrogen bond donor (HBD) to construct NADES. This extracting agent was deployed to separate the polyphenolic compounds from the stem of Jotang (Spilanthes acmella) under prime conditions. The extracted polyphenol was subsequently calculated based on the Folin-Ciocalteu method using gallic acid as the standard solution by UV-Vis spectrophotometer at 760 nm. Corresponding to the research outcomes, the most gainful states of extraction were achieved at a sample weight-to-NADES volume ratio of 1:50, a period of extracting process of 60 min, water content of 20%, and a stirring speed of 80 rpm. The optimized parameters were conceived as the most gainful because they exhibited the most prominent level of polyphenol were described as follows: ratio of sample weight-to-NADES volume and extraction time showed polyphenol content of 25.13 mg GAE/g each, while the others, stirring speed and water content revealed the polyphenol concentration of 25.75 mg GAE/g respectively.
Co-Authors Iwan Safrudin Maimulyanti, Askal Mellisani, Bella Mualim, Ahmad Dzaky Nurhidayati, Isna Puspita, Fitria Putri, Fajar Amelia Rachmawati Styani, Erna Widarsih, R. Wiwi