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Chemical Composition, Phytochemical Screening and Antioxidant Activity of Acmella uliginosa (Sw.) Cass Leaves Askal Maimulyanti; Anton Restu Prihadi; Iwan Safrudin
Indonesian Journal of Chemistry Vol 16, No 2 (2016)
Publisher : Universitas Gadjah Mada

Acmella uliginosa (Sw.) Cass is widely used in traditional medicine and used in the treatment of many diseases. Extraction of component in leaves of Acmella uliginosa used methanol, ethyl acetate and n-hexane solvent. The percentage yield of extract from the leaves in methanol, ethyl acetate and n-hexane were 6.50, 0.49, and 0.66, respectively. Analysis of component in various extracts of Acmella uliginosa (Sw.) Cass leaves used Gas Chromatography-Mass Spectrometry (GC-MS). The various classes of phytochemicals were identified from fractions of methanolic leaves extract by GC-MS. Qualitative analysis of phytochemical constituents in methanol, ethyl acetate and n-hexane extract were tannins, flavonoids, saponin, alkaloid and steroid. Antioxidant activity of Acmella uliginosa leaves from Indonesia was carried out by using 1,1,diphenyl-2-picryl-hydrazine (DPPH) free radical scavenging assay. The IC50 of three extract was calculated. A comparative study determined that Acmella uliginosa in ethyl acetate extract showed the highest antioxidant potential (IC50 = 28.09 µg/mL) compared to methanol extract (IC50 = 44.31 µg/mL) and n-hexane extract (181.23 µg/mL) against DPPH free radicals.

Effect of Salinity and Oxygen Condition on Phosphate Release from Marine Sediment Measured Using Diffusive Gradient in Thin Film (DGT) Technique Askal Maimulyanti; Budiawan Budiawan; Asep Saefumillah; Heny Suseno
Indonesian Journal of Chemistry Vol 19, No 3 (2019)
Publisher : Universitas Gadjah Mada

The diffusive gradient in thin film (DGT) is an analytical technique to determine phosphate in the environment. This technique uses a thin film diffusive hydrogel in contact with a binding phase (ferrihydrite) to binding of phosphate. The released phosphate from marine sediment of Jakarta Bay was studied by DGT technique for effect of salinity and oxygen condition. Effect of salinity was observed by NaCl concentration from 0-35 g/L. The maximum phosphate release from sediment was occurred at the concentration of NaCl 30 g/L with incubation for 15 days with phosphate released at 113.99 μg/L, MDGT of 4.7723 μg and CDGT of 17.56 μg/L. The experiment showed the increase of MgCl2 and CaCl2 concentration reduced phosphate release from sediment. The condition of oxygen indicating the release of phosphate under anaerobic conditions is greater than the aerobic condition. The aerobic conditions with incubation for 21 days showed the release of phosphate from sediment to overlying water of 124.72 μg/L, MDGT of 2.4492 μg and CDGT of 6.4380 μg/L. Anaerobic conditions with incubation for 21 days showed phosphate release from sediment to overlying water of 208.62 μg/L, MDGT of 6.1081 μg and CDGT of 16.06 μg/L. The experiment shows that salinity and oxygen concentration influences phosphate release from marine sediment of Jakarta Bay.

Optimasi Proses Produksi Tahu Bandung dan Penerapan Industri 4.0 Di IKM Tahu Tansa Bogor Prihadi, Anton Restu; Maimulyanti, Askal; Styani, Erna; Mualim, Ahmad Dzaky; Puspita, Fitria; Putri, Fajar Amelia Rachmawati
Jurnal Pengabdian Masyarakat AKA Vol 4, No 2 (2024): Desember 2024
Publisher : Politeknik AKA Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55075/jpm-aka.v4i2.254

IKM Tahu Tansa merupakan salah satu IKM di Kota Bogor yang memproduksi Tahu Bandung. Seiring dengan perkembangan waktu dan peningkatan produksi, IKM mengalami beberapa permasalahan seperti konsistensi kualitas organoleptik tahu yang disebabkan oleh suhu pemasakan dan penambahan garam yang tidak konsisten selain itu keterbatasan alat pada proses penyaringan kedelai. Pada akhirnya, hal ini dapat menimbulkan resiko penurunan kualitas dan kuantitas produksi tahu dan berpotensi meningkatkan biaya produksi yang berdampak pada lonjakan harga jual tahu. Berdasarkan permasalahan tersebut, tim PkM Politeknik AKA Bogor bermaksud untuk memberikan alternatif solusi penyelesaian permasalahan yang dihadapi yaitu berupa pelatihan metode pengawasan suhu pemasakan agar optimum menggunakan teknologi arduino. Aplikasi ini akan memudahkan pekerja untuk memantau suhu sebenarnya di dalam kuali masak. Proses pemasakan yang optimum akan menyebabkan matinya seluruh bakteri patogen yang terdapat pada adonan tahu. Efektivitas proses pemasakan ini akan dipantau melalui analisis mikrobiologi. Sedangkan konsistensi penambahan garam pada adonan tahu akan dipantau menggunakan titrimetri metode Mohr. Setelah diuji mutunya terkait kadar garam dan kadar mikroba dapat disimpulkan bahwa tahu bandung yang diproduksi IKM memiliki kualitas yang konsisten dan bebas dari bakter E.coli

Extraction of Polyphenol From Turmeric (Curcuma longa), Red Ginger (Zingiber officinale), and Aromatic Ginger (Kaempfeiria galanga l) Using Natural Deep Eutectic Solvent Based On Choline Chloride and Sugar Maulia, Gina; Maimulyanti, Askal; Nurhidayati, Isna; Mellisani, Bella; Nurhasanah, Nurhasanah
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 7, No 1 (2025)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v7i1.45812

Indonesia is a tropical country rich in biodiversity, including a wide variety of herbal plants. Herbs and spices are abundant in Indonesia and have been used in local customs since ancient times. Turmeric, ginger, and curcuma are rhizomes used as spices in Indonesian cooking and natural medicine. This study investigates the efficiency of natural deep eutectic solvents (NADES) synthesized from choline chloride and various sugars—fructose, glucose, maltose, and xylose in extracting polyphenolic compounds from Indonesian rhizomes: turmeric (Curcuma longa), red ginger (Zingiber officinale), and aromatic ginger (Kaempferia galanga L). The NADES were prepared using choline chloride as hydrogen bond acceptor (HBA). The hydrogen bond donor (HBD) is a sugar such as fructose, xylose, maltose, and glucose. The total phenolic content (TPC) was quantified and reported in mg gallic acid equivalent (GAE)/g extract. Kaempferia galanga exhibited the highest TPC among the rhizomes, reaching 32.21 mg GAE/g when extracted with ChCl–Fructose NADES. Curcuma longa and Zingiber officinale yield 20.05 mg GAE/g and 25.84 mg GAE/g under the same solvent conditions, respectively. When comparing the performance of the solvents, the following order was observed: ChCl–Fr > ChCl–Xyl > ChCl–Mal > ChCl–Glu. These findings suggest that solvent polarity and hydrogen bonding capacity significantly influence polyphenol solubility and extraction efficiency. NADES based on ChCl–Fructose showed the greatest potential for eco-friendly extraction of bioactive phenolics from medicinal rhizomes.

Extraction of Polyphenol From Turmeric (Curcuma longa), Red Ginger (Zingiber officinale), and Aromatic Ginger (Kaempfeiria galanga l) Using Natural Deep Eutectic Solvent Based On Choline Chloride and Sugar Maulia, Gina; Maimulyanti, Askal; Nurhidayati, Isna; Mellisani, Bella; Nurhasanah
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 7 No. 1 (2025)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v7i1.45812

Indonesia is a tropical country rich in biodiversity, including a wide variety of herbal plants. Herbs and spices are abundant in Indonesia and have been used in local customs since ancient times. Turmeric, ginger, and curcuma are rhizomes used as spices in Indonesian cooking and natural medicine. This study investigates the efficiency of natural deep eutectic solvents (NADES) synthesized from choline chloride and various sugars—fructose, glucose, maltose, and xylose in extracting polyphenolic compounds from Indonesian rhizomes: turmeric (Curcuma longa), red ginger (Zingiber officinale), and aromatic ginger (Kaempferia galanga L). The NADES were prepared using choline chloride as hydrogen bond acceptor (HBA). The hydrogen bond donor (HBD) is a sugar such as fructose, xylose, maltose, and glucose. The total phenolic content (TPC) was quantified and reported in mg gallic acid equivalent (GAE)/g extract. Kaempferia galanga exhibited the highest TPC among the rhizomes, reaching 32.21 mg GAE/g when extracted with ChCl–Fructose NADES. Curcuma longa and Zingiber officinale yield 20.05 mg GAE/g and 25.84 mg GAE/g under the same solvent conditions, respectively. When comparing the performance of the solvents, the following order was observed: ChCl–Fr > ChCl–Xyl > ChCl–Mal > ChCl–Glu. These findings suggest that solvent polarity and hydrogen bonding capacity significantly influence polyphenol solubility and extraction efficiency. NADES based on ChCl–Fructose showed the greatest potential for eco-friendly extraction of bioactive phenolics from medicinal rhizomes.

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