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All Journal JFM (Jurnal Farmasi Malahayati) Jurnal Ilmiah Medicamento
Mahardika, Ida Bagus Putra
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Environmental Science Health Professions Medicine & Pharmacology Public Health

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AKTIVITAS ANTIOKSIDAN DAN PROFIL FITOKIMIA DARI EKSTRAK DAUN PACAR AIR (Impatiens balsamina L.) DENGAN VARIASI PELARUT Mahardika, Ida Bagus Putra; nugraha, iwan saka; Yuliana, ni luh Diah
JFM (Jurnal Farmasi Malahayati) Vol 8, No 2 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i2.20737

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh variasi pelarut terhadap aktivitas antioksidan ekstrak daun pacar air (Impatiens balsamina L.) dengan metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Ekstraksi dilakukan dengan metode maserasi menggunakan tiga jenis pelarut, yaitu etanol 96%, n-heksana, dan aquadest. Hasil rendemen menunjukkan pelarut etanol 96% memberikan hasil tertinggi sebesar 17,64%, diikuti aquadest 13,13% dan n-heksana 9,45%. Skrining fitokimia terhadap ekstrak etanol menunjukkan adanya senyawa alkaloid, flavonoid, tanin, saponin, steroid dan terpenoid. Pengujian aktivitas antioksidan dilakukan pada lima konsentrasi (60, 70, 80, 90, dan 100 ppm) menggunakan spektrofotometer UV-Vis pada panjang gelombang 515 nm. Hasil penelitian menunjukkan nilai IC₅₀ ekstrak etanol 96% sebesar 4,06 ppm (kategori sangat kuat), aquadest sebesar 6,24 ppm (sangat kuat), dan n-heksana sebesar 10,53 ppm (sangat kuat). Pemberian variasi pelarut berpengaruh signifikan terhadap aktivitas antioksidan ekstrak daun pacar air, dan pelarut etanol 96% merupakan pelarut paling efektif dalam mengekstrak senyawa antioksidan. 
Analisis Bibliometrik Formulasi Poliherbal sebagai Afrodisiak: Tinjauan Tren Penelitian Terkini Kartika, I Gusti Agung Ayu; Nugraha, Iwan Saka; Mahardika, Ida Bagus Putra; Suryani, Suryani
Jurnal Ilmiah Medicamento Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento (In progress)
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i2.11418

Abstract

In recent years, the therapeutic potential of polyherbal formulations as aphrodisiacs, particularly as natural alternatives to synthetic treatments for sexual health disorders, has garnered significant attention. Polyherbal formulations are believed to enhance efficacy through synergistic effects, making them a preferred option in both traditional and modern therapeutic practices. This review aims to provide a comprehensive analysis of research trends relating to the use of polyherbal formulations for aphrodisiac purposes. A bibliometric analysis was conducted using the Scopus database, extracting relevant articles with the keywords 'Aphrodisiac AND Polyherbal OR Combination.' From an initial pool of 88 articles, 16 were selected for in-depth analysis. VOSviewer software was used to visualize collaboration networks, co-authorship patterns, and keyword trends, highlighting the increasing research interest in polyherbal formulations for sexual health enhancement. The narrative review supplements these findings by exploring study methodologies, sources of herbal ingredients, formulation compositions, and commonly used herbs. Results indicate that while polyherbal aphrodisiac formulations show promising therapeutic potential, research in this field remains fragmented, with limited clinical trials evaluating safety and efficacy. The most frequently studied herbs include Tribulus terrestris, Mucuna pruriens, and Withania somnifera, known for their effects on testosterone levels, vascular function, and libido enhancement. Future studies should focus on clinical validation, standardization, and pharmacokinetic assessments to facilitate their integration into modern medical practice. These findings provide valuable insights for researchers and industries developing polyherbal-based nutraceutical and pharmaceutical products.
Co-Authors I Gusti Agung Ayu Kartika Iwan Saka Nugraha Nugraha, Iwan Saka Suryani Suryani Yuliana, ni luh Diah