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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Penelitian Farmasi Indonesia
Rahayu Utami
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Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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FORMULASI DAN PENENTUAN NILAI SUN PROTECTION FACTOR (SPF) SEDIAAN KRIM TABIR SURYA EKSTRAK ETANOL BEKATUL PADI BERAS MERAH (Oryza sativa L) Wira Noviana Suhery; Novita Dewi; Rahayu Utami; Mustika Furi; Melzi Octaviani
Jurnal Penelitian Farmasi Indonesia Vol. 10 No. 1 (2021): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v10i1.1408

Abstract

Study of formulation of sunscreen cream with ethanolic extract of red rice bran (Oryza sativa L) and determining the SPF value in vitro using a UV spectrophotometer has been carried out. Ethanol extract of red rice bran has been shown antioxidant activity. Determining the SPF value due to determine the ability of the red rice bran ethanol extract to protect the skin from UV radiation. Ethanol extract of red rice bran was formulated in the form of a cream type o/w of F1 and F2 containing extract concentrations of 5% and 10%, respectively. Based on the research conducted, it was found that F2 had a higher SPF value of 13,098 than F1 of 11,861. Based on the SPF value generated from the formula, this study showed that the sunscreen cream preparation of red rice bran extract can protect the skin from UV radiation maximally for 110-130 minutes.
Isolasi Metabolit Sekunder dari Ekstrak Etil Asetat Kulit Batang Meranti Rambai (Shorea acuminata Dyer) Enda Mora; Septi Muharini; Emrizal Emrizal; Rahayu Utami; Mella Silfia Andriani
MPI (Media Pharmaceutica Indonesiana) Vol. 1 No. 1 (2016): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (559.878 KB) | DOI: 10.24123/mpi.v1i1.36

Abstract

Telah dilakukan isolasi dan pengujian sitotoksik ekstrak etil asetat kulit batang merantirambai (Shorea acuminata Dyer). Ekstraksi dilakukan dengan maserasi bertingkat dan uji sitotoksikdengan metode Brine Shrimp Lethality Test (BSLT). Isolasi dilakukan dengan kromatografi kolommemakai sistem gradient dan diperoleh senyawa D1, berupa amorf berwarna putih sebanyak18 mg dengan titik leleh 280-282oC. Berdasarkan hasil reaksi dengan reagen Liebermann-Buchard(yaitu warna orange kecoklatan) dan hasil karakterisasi dengan spektroskopi UV, IR, 1H-RMI, dan 13CRMI,maka dapat disimpulkan bahwa senyawa D1 termasuk golongan terpenoid. Dari hasil pengujiansitotoksik ekstrak etil asetat didapatkan nilai LC50 sebesar 3,68 ppm dan dapat dinyatakan bahwaekstrak etil asetat kulit batang meranti rambai memiliki sifat sangat toksik terhadap kematian Artemiasalina Leach.
Co-Authors Emrizal Emrizal Enda Mora Furi, Mustika Mella Silfia Andriani Melzi Octaviani Novita Dewi Septi Muharini Wira Noviana Suhery