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Mild Cognitive Impairment (MCI): Transisi dari Penuaan Normal Menjadi Alzheimer Rilianto, Beny
Cermin Dunia Kedokteran Vol 42, No 5 (2015): Kardiologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (647.797 KB) | DOI: 10.55175/cdk.v42i5.1009

Abstract

Gangguan kognitif ringan atau mild cognitive impairment (MCI) mengacu pada keadaan transisi antara perubahan kognitif karena usia dan gambaran awal demensia. MCI umumnya dibagi menjadi dua kategori, yaitu amnestic dan non-amnestic. Individu dengan MCI memiliki peningkatan risiko terkena penyakit Alzheimer, terutama jika masalah utama adalah memori. Deteksi dan intervensi dini akan mengurangi risiko perkembangan penyakit Alzheimer dan demensia lain setelah terjadi MCI.Mild cognitive impairment (MCI) refers to the transitional state between the cognitive changes due to age and the beginning of dementia. MCI is usually classified into amnestic and non-amnestic categories. Individuals with MCI have an increased risk of developing Alzheimer's disease, especially if the main problem is memory. Early detection and intervention is important to reduce the risk of developing Alzheimer's disease and other dementias after MCI.
Evaluasi dan Manajemen Status Epileptikus Rilianto, Beny
Cermin Dunia Kedokteran Vol 42, No 10 (2015): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.28 KB) | DOI: 10.55175/cdk.v42i10.958

Abstract

Status epileptikus (SE) membutuhkan penanganan awal yang cepat. Kehilangan autoregulasi serebral dan kerusakan neuron dimulai setelah 30 menit aktivitas kejang yang terus-menerus. Penilaian awal berfokus pada kemungkinan adanya gangguan metabolik ataupun kondisi yang membutuhkan tatalaksana segera. Penatalaksanaan tahap awal menyarankan penggunaan benzodiazepin dan fenitoin untuk menghentikan kejang, anestesi dipertimbangkan pada SE refrakter. Prognosis SE sangat bergantung pada etiologi yang mendasarinya.Status epilepticus (SE) requires immediate initial treatment. Loss of cerebral autoregulation and neuronal damage begin after 30 minutes of continuous seizure activity. Initial assessments focus on a possibility of underlying metabolic disorders or condition that requires immediate management. Early management use benzodiazepines and phenytoin to terminate seizures, the use of anesthesia is considered in refractory SE. Prognosis of SE is dependent on the underlying etiology. 
Terapi Trombolitik Intravena untuk Stroke Iskemik Akut - Hambatannya di Negara Berkembang Rilianto, Beny
Cermin Dunia Kedokteran Vol 43, No 12 (2016): Kardiovaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.912 KB) | DOI: 10.55175/cdk.v43i12.904

Abstract

Terapi trombolitik dengan tPA merupakan terapi yang direkomendasikan oleh Heart American Heart Association/American Stroke Association (AHA/ASA) dan European Stroke Organization (ESO) untuk pasien dengan stroke iskemik akut yang memenuhi kriteria inklusi dan eksklusi. Namun demikian, negara berkembang masih mempunyai mortalitas dan angka kecacatan stroke yang tinggi; jumlah pasien yang mendapat tPA di negara berkembang masih sangat rendah. Hambatan dapat terjadi pada fase pre-hospital, in-hospital, serta kurangnya infrastruktur, dan hambatan finansial. Negara berkembang hendaknya berfokus pada strategi prevensi stroke, namun seharusnya juga mengupayakan infrastruktur untuk pelayanan stroke.Thrombolytic therapy with tPA is a therapy recommended by the Heart American Heart Association/American Stroke Association (AHA/ASA) and the European Stroke Oraganization (ESO) for acute ischemic stroke patients with eligible criteria. However, developing countries still have a high stroke mortality and high disability rate; patients who received tPA treatment in developing countries are still very low. Barriers can occur in pre-hospital, in-hospital setting, lack of infrastructure to facilitate thrombolytic therapy, and financial constraint. Developing countries should focus on stroke prevention strategies; however, developing countries should also provides infrastructures for stroke care.
Challenging Endovascular Treatment of Ruptured Proximal Posterior Inferior Cerebellar Artery Aneurysm: A Case Report Prasetyo, Bambang Tri; Kurniawan, Ricky Gusanto; Rilianto, Beny; Windiani, Pratiwi Raissa; Kelvin, Kelvin Theandro
AKSONA Vol. 4 No. 1 (2024): JANUARY 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v4i1.44640

Abstract

Highlight: Posterior inferior cerebellar artery (PICA) aneurysms are rare in occurence. The endovascular management of PICA aneursysms is challenging due to anatomical difficulties in accessing the site. The rebleeding of PICA aneurysms, although rare than other intracranial anurysms, may still happen and must be considered in their management   ABSTRACT Introduction Aneurysms of the posterior inferior cerebellar artery (PICA) are rare clinical entities with a lower risk of rupture than other intracranial locations. This makes managing PICA aneurysms challenging and important for neurointerventionists to understand. In this case report, we looked at a rare case of PICA aneurysm with post-coiling rebleeding.  Case: We reported a 51-year-old female with complaints of dizziness and vomiting. The patient was found to be hypertensive and a neurologic assessment revealed neck stiffness and left hemiparesis. A computed tomography (CT) scan of the head indicated subarachnoid hemorrhage. CT angiography (CTA) showed an aneurysm at the right proximal PICA. Although endovascular coiling was performed, the patient rebleed one month later. Following the insertion of the second coil, successful embolization was achieved, and the patient showed clinical improvement. Conclusion: PICA aneurysms require careful endovascular management, considering the difficulty of access due to their anatomical location. An understanding of its proper management is of paramount importance to reducing mortality.  
Perdarahan Intrakranial Pasca Terapi Trombolisis Stroke Iskemik Akut pada Populasi Asia Rilianto, Beny; Helda, Helda
Jurnal Ilmiah Kesehatan Vol 14 No 1 (2022): Jurnal Ilmiah Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/jik.v14i1.860

Abstract

Terapi trombolisis dengan tPA (tissue Plasminogen Activator) merupakan terapi yang direkomendasikan pada stroke iskemik akut dengan onset kurang dari 4,5 jam. Namun terapi trombolisis memiliki komplikasi perdarahan intrakranial yang bervariasi di antara populasi diberbagai negara dan masih sedikitnya informasi perdarahan intrakranial pada populasi Asia. Penelitian dilakukan dengan metode kajian literature. Penelitian literature didapatkan dari data base online Google Scholar dan PubMed sesuai kriteria inklusi dan eksklusi ditemukan 11 artikel. Dari 11 artikel tersebut didapatkan pada populasi Asia perdarahan lebih tinggi jika menggunakan tPA dengan dosis standar dibanding dosis rendah. Beberapa faktor yang meningkatkan risiko perdarahan adalah derajat stroke, waktu pemberian tPA sejak onset gejala dan riwayat diabetes melitus. Perdarahan intrakanial merupakan salah satu komplikasi fatal yang penting pasca terapi trombolisis yang dapat meningkat seiring dengan faktor risiko tertentu, dan bervariasi antar studi di beberapa negara.
Stand-alone middle meningeal artery embolization in chronic subdural hematoma patient presenting cognitive decline: a case report Galindra, Yusmahenry; Rilianto, Beny; Kurniawan, Ricky Gusanto; Prasetyo, Bambang Tri
Medical Journal of Indonesia Vol. 33 No. 4 (2024): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.cr.247366

Abstract

Chronic subdural hematoma (cSDH) is a neurological disorder that commonly occurs in the elderly with high morbidity and mortality. Current treatment for cSDH consists of conservative therapy, surgical evacuation, and endovascular therapy, or a combination of all the methods. Endovascular therapy for cSDH management involving middle meningeal artery embolization (MMAE) has become a promising therapeutic option for clinicians as it offers a minimally invasive, safe, and effective choice with a low recurrence rate. MMAE using particles can also be performed in frail elderly patients who cannot undergo large craniotomy procedures. We presented a case of a subdural hematoma patient with cognitive decline using a therapeutic strategy of stand-alone MMAE, which resulted in cognitive function improvement