Hermawan, Melyawati
Department Of Dermatology And Venerology, Faculty Of Medicine, Atma Jaya Catholic University Of Indonesia Jakarta, Indonesia

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Uncontrolled blood sugar tends to increase prevalence of dermatomycosis in diabetic type 2 patients Surja, Sem Samuel; Hermawan, Melyawati; Wijaya, Meiliyana; Pramanta, Pramanta; Yolanda, Hanna
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (729.675 KB) | DOI: 10.18051/UnivMed.2018.v37.188-194

Abstract

Background The prevalence of type 2 diabetes mellitus (DM) is increasing. Diabetic patients have a higher risk of getting dermatomycosis. Dermatomycoses, although a common health problem amongst DM, is often misdiagnosed and consequently undertreated. Studies on the association between dermatomycosis and type 2 diabetes are lacking, especially in Indonesia. Therefore, the aim of this study was to determine the prevalence, etiology, and association of dermatomycosis with diabetic control of type 2 DM. MethodsA cross-sectional study was performed involving 87 subjects with type 2 DM. Demographic and clinical data, including age, sex, and blood glucose level, were collected. If a dermatomycosis lesion was found, a specimen would be taken for identification. Determination of serum glucose level was conducted using Roche c111 analyzer®. Statistical analysis was performed with the chi-square test and Kolmogorov-Smirnov two-independent sample test.ResultsSeventeen (19.55%) subjects had dermatomycosis. The predominant age group affected was 51 - 60 years (42.4%). The number of clinically apparent dermatomycosis was greater in the uncontrolled than in the controlled blood sugar group, but the difference was statistically not significant (p > 0.05). The lesions were mostly found on the nails (74%) and the most common etiology was candida (50%) followed by dermatophyte (25%) and non-dermatophyte molds (25%). ConclusionUncontrolled blood sugar tends to increase the risk of dermatomycosis in type 2 DM patients. Fungal skin infections are common in type-2 DM patients, especially in those with poor glycemic control.
Psychosocial Burden Due to Acne Vulgaris Affects Treatment-Seeking Behavior in Medical Students in Jakarta, Indonesia Franklind Matthew; Regina Regina; Inneke Jane Hidajat; Melyawati Melyawati
Althea Medical Journal Vol 8, No 3 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v8n3.2179

Abstract

Background: Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit of the skin that occurs in 85% of adolescents and can continue into adulthood. The skin of the facial area has an essential role in socializing, therefore, facial AV can contribute to the accumulation of psychosocial stress. The prevalence of individuals with AV seeking treatments is low in some countries. This study aimed to determine the association between psychosocial burdens due to AV and medical treatment-seeking behavior in young adults. Methods: A cross-sectional study was conducted in February 2020 among 100 medical students with AV. The ASEAN Lehmann criteria were used to objectively assessed AV. Psychosocial burden was determined by the Cardiff Acne Disability Index (CADI) questionnaire and then classified into unaffected (score 0), mild (score 1-5), moderate (6-10), and severe (11-15). History-related AV was obtained through a questionnaire. The analysis was performed using the chi-square test.Results: Of the 100 medical students with AV, 82% had suffered from mild to severe psychosocial burdens. The mean score of the CADI was 4.03. However, only 44% of students sought treatment from doctors for their AV. There was a significant association between psychosocial burden and medical treatment-seeking behavior (p = 0.014).Conclusion: The psychosocial burden of acne vulgaris in young adults is high, however, medical treatment-seeking behavior is low. Therefore, psychosocial management is an essential aspect in treating patients with AV.
The association between blotting paper application and severity of acne vulgaris among medical students Alberta, Ivana Beatrice; Hermawan, Melyawati; Ali, Soegianto
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Acne vulgaris is an inflammatory condition of the pilosebaceous glands caused by various factors including excessive excretion of sebaceous glands. Excess sebum can be reduced using oil blotting paper (OBP), a thin paper with microspores that absorb the oil on the face. This study was conducted to determine the association between OBP application and sebum excretion according to the Oily Skin Self- Assessment Scale (OSSAS) questionnaire and acne severity according to the Global Acne Grading System (GAGS) questionnaire. Methods: This experimental study was conducted in 2017 among 60 students aged 17–22 years at the Faculty of Medicine, Atma Jaya Catholic University of Indonesia, recruited by purposive sampling. Data on sebum excretion and the degree of AV severity before and after intervention were analyzed using the chi- square test with a significant level of p < 0.05. Results: Before intervention, 11 (18.3%) students had dry skin, 23 (38.3%) had slightly dry skin, 17 (28.4%) had slightly oily skin, and 9 (15%) had oily skin. The prevalence of AV was 100%, with 48 (80%) students having mild severity and the remaining having moderate severity. There was no effect of using OBP on sebum excretion (p = 0.211); however, an improvement was noted on GAGS raw data score (p < 0.001). Conclusion: AV is an inflammatory disease of the pilosebaceous glands, and one of the etiologies is excessive sebum excretion, which can be reduced using OBP. This study demonstrated that OBP application did not reduce sebum excretion statistically but could improve the severity of AV.
Prevalence of Cutibacterium acnes and Staph spp. in the lesions of acne vulgaris in Jakarta Hermawan, Melyawati; Tjoa, Enty; Hidajat, Inneke J.; Teressa, Maria; Layadi, Eka B.; Wolter, Alegra
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Acne vulgaris (AV) is a chronic skin disorder that is commonly seen in young adults. Recent studies have shown that bacteria other than Cuticubacterium acnes found in the skin microbiota also play vital roles in the pathogenesis of AV. Understanding the skin microbiota and its disruption in patients with AV is paramount in treating patients with AV. Methods: Samples were obtained from 36 subjects to evaluate the proportion of Cutibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus in lesions of AV by means of bacterial culture. Results: There were 69 specimens collected from the 36 subjects with AV. The most abundant type of bacteria that was successfully isolated in the cultured AV lesions was Staphylococcus epidermidis(46.4%), followed by Cutibacterium acnes(14.5%), and Staphylococcus aureus(2.9%). Conclusion: Staphylococcus epidermidis,the major species of human skin flora, is the most abundant microorganism found in AV. The development of AV is not necessarily associated with the high proportion of Cutibacterium acnes. More pathogenic bacteria, such as Staphylococcus aureusis also not always found in the AV lesions. These findings may provide the basis for the clinicians to determine which types of antibiotics to prescribe for the treatment of AV.
The effect of topical oatmeal (Avena sativa) on hydration-related skin disorders: A systematic review Sugondo, Karenina Novani; Hermawan, Melyawati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: In recent years, interest in developing cosmetics and beauty products based on natural ingredients has increased. The addition of herbal extracts to products could improve the effectiveness of therapy. One of the natural ingredients that can be found is oatmeal. Oatmeal has been used for a long time and has been approved by the U.S. Food and Drug Administration as a skin protective agent since 2003. This study aims to systematically review the literature to determine the effect of topical oatmeal (Avena sativa) on hydration-related skin disorders. Methods: A total of 9,538 studies were found in the database sources such as PubMed, ProQuest, Clinical Key, Cochrane, Clinical Trial, and EBSCO. The inclusion criteria were all randomized controlled trials published from 2010 to 2020 that evaluated the effect of oatmeal-contained moisturizers on hydration-related skin disorders. The risk of bias was assessed using the Cochrane risk-of-bias tool for randomized trials (RoB2). Result: A total of five studies were included in this systematic review. These studies were published in 2015-2020. The forms of oatmeal in the five studies differ, such as emollient, lotion, and cream extracts. The skin disorders in the literature also vary, such as chronic pruritus, uremic pruritus, atopic dermatitis, irritant hand eczema, and dry skin. Conclusion: Although the form of oatmeal, skin disorders, and age range in each literature differ, it can be concluded that an oatmeal-contained moisturizer could improve the clinical assessment and the objective measurement of various hydration-related skin conditions.
Olive oil and hydration based on clinical assessment and transepidermal water loss: A systematic review Paramitha Jaya, Ni Made Ayu Nadia; Hermawan, Melyawati; Regina, Regina
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 2
Publisher : UI Scholars Hub

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Background: Dry skin or xerosis is a layer of skin that loses moisture due to increased transepidermal water loss (TEWL). Olive oil, one of the most commonly available moisturizers, is often used to keep the skin hydrated. Skin hydration indicates the amount of water in the stratum corneum. This systematic review aimed to determine the association between olive oil application and skin hydration based on clinical assessment and TEWL parameters. Methods: The research design used was a systematic review based on the criteria of preferred reporting items for systematic reviews and meta-analyses (PRISMA). This systematic review search used PubMed, ProQuest, Google Scholar, CINAHL, and NLM Catalog databases. The risk of bias in the literature used in this study was assessed using the Revised Cochrane risk-of-bias tool for randomized trials (RoB 2). Results: Five articles were included in this systematic review in which topical intervention on the skin was used with olive oil and other oils, placebo, or no therapy as controls. Olive oil can improve skin conditions clinically and provide various beneficial effects such as antioxidants and anti-inflammatory, but the oleic acid content, which is the main component of olive oil, has detrimental effects on the skin. Conclusion: This systematic review reveals that olive oil can improve skin condition clinically, but long-term topical application of olive oil may damage the integrity of the skin and increase TEWL.