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Retinopati Klorokuin dan Hidroksiklorokuin Alberta, Ivana Beatrice; Tri Ekaputri, Maria Vania; Amita, Angela Shinta Dewi
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1038.997 KB) | DOI: 10.55175/cdk.v47i10.1081

Abstract

Klorokuin dan hidroksiklorokuin kerap digunakan sebagai tatalaksana berbagai penyakit autoimun, infeksi malaria, dan kini menjadi salah satu obat penanggulangan darurat Coronavirus Disease-19 (COVID-19). Kedua obat ini berpotensi sebagai antiinflamasi dan antivirus. Namun penggunaannya sering menimbulkan berbagai efek samping seperti pada jantung, saraf, saluran pencernaan, dan juga mata. Efek samping pada mata dapat berupa toksisitas retina yang dapat berakhir menjadi retinopati ireversibel. Guna menghindari cacat permanen, diperlukan pencegahan yang tepat dengan mengenali faktor risiko dan skrining, serta pemantauan ketat penggunaan obat.Chloroquine and hydroxychloroquine are often used as a treatment for autoimmune disease, malaria infection, and now become an emergency drug for Coronavirus Disease-19 (COVID-19). Both are potential anti-inflammatory and antiviral agents. However, potential various side effects to the heart, nerves, gastrointestinal tract, and also eyes must be considered. Side effects on the eyes are retinal toxicity which can end up as irreversible retinopathy. Proper prevention is needed by recognizing risk factors and screening, as well as strict monitoring of drug use.
Uji Coba Modul Yoga untuk Mengatasi Insomnia Tingkat Ringan-sedang pada Mahasiswa Kedokteran Lilis; Lilis, Lilis; Kodrata, Grace Angelica; Ayu, Astri Parawita; Amita, Angela Shinta Dewi
Bahasa Indonesia Vol 23 No 1 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i1.4559

Abstract

Pendahuluan: Insomnia adalah gangguan tidur yang paling umum terjadi. Gejalanya dapat berupa sulit untuk tertidur, sering terbangun pada malam hari dan tidak dapat tertidur kembali, bangun terlalu dini, atau bangun dengan kondisi kurang segar. Mahasiswa kedokteran merupakan salah satu kelompok yang rentan untuk memiliki insomnia. Kualitas tidur yang buruk dapat mengganggu kinerja kognitif dan motorik. Yoga dilaporkan dapat memberikan efek relaksasi sehingga dapat mengurangi gejala insomnia. Uji coba modul ini mengetahui pengaruh yoga terhadap insomnia tingkat ringan-sedang pada mahasiswa kedokteran. Metode: Studi ini merupakan uji coba modul dengan menggunakan kelompok studi dan kelompok kontrol. Total partisipan ada 16 orang yang memenuhi kriteria penelitian. Instrumen yang digunakan adalah kuesioner Insomnia Severity Index (ISI) untuk mengukur derajat insomnia dan 17 pertanyaan mengenai modul yoga. Intervensi latihan yoga dilakukan selama 8 minggu. Analisis data menggunakan uji-t berpasangan untuk mengetahui perubahan rerata skor ISI sebelum dan sesudah intervensi. Hasil: Uji statistik menunjukkan adanya perbedaan yang signifikan antara rerata skor ISI pre-intervention dan post-intervention (p<0,001) pada kelompok studi. Modul yoga juga dapat diikuti dengan baik oleh partisipan. Simpulan: Penelitian ini mengindikasikan bahwa latihan yoga berdasarkan modul yang telah disusun dapat mengurangi gejala insomnia pada mahasiswa kedokteran. Modul yoga juga dapat diikuti dengan baik oleh partisipan.
Effect of Yoga on Anxiety Levels among Medical Students During COVID-19 Pandemic Prameswari, Yovita Rinda; Amita, Angela Shinta Dewi; Gracia, Isadora; Lilis, Lilis
Althea Medical Journal Vol 11, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n2.3173

Abstract

Background: The COVID-19 pandemic became one of the factors that caused anxiety among medical students. Anxiety needs to be managed before it develops into a disorder. Yoga as a complementary therapy can reduce anxiety. This study aimed to determine the effectiveness of yoga on anxiety levels among medical students.Methods: This was a quasi-experimental study conducted in February–September 2022 and participated by medical students at the Atma Jaya Catholic University of Indonesia experienced anxiety. Participants were divided into two groups; an intervention group and a control group. Anxiety levels were measured using the Depression Anxiety Stress Scale 42 (DASS-42) questionnaire. The intervention provided was the Atma Jaya Yoga Intervention Studies (AJYOGIS) procedure for nine weeks. Yoga practice was performed online via Zoom and offline on campus. The Shapiro-Wilk test  was used to test data distribution, Paired Sample T-Test and Wilcoxon Signed-Rank test to observe changes within groups. The changes between groups were analyzed using Unpaired Sample T-Test and Mann-Whitney test. A p-value of <0.05 was considered statistically significant.Results: Of the 36 medical students participated, the anxiety level of most participants was in the moderate category (41.7%).  There was a significant decrease in anxiety scores in the intervention and control group after practicing yoga (p<0.05). However, there was no significant change in the anxiety category in the control group (p=0.231).Conclusion: Yoga can reduce anxiety levels, especially during the COVID-19 pandemic. Further detailed analysis with a larger sample size is needed to strengthen these findings.
Effect of Surya Namaskar yoga practice on flexibility in the pre-elderly and elderly Karasugi, Ni Made Ayu Regina; Lilis, Lilis; Amita, Angela Shinta Dewi; Novi Handayani, Maria Dara; Prastowo, Nawanto Agung
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 4 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005504202304

Abstract

Anatomical and physiological changes occur along with the aging process. One of the changes is decreased flexibility due to changes in the musculoskeletal system. Upper and lower limb flexibility is closely related to the ability to carry out daily activities, which affects the quality of life of the elderly. Surya  Namaskar yoga is known to help increase flexibility because it integrates stretching components within its movement. This study aimed to investigate the effect of Surya  Namaskar on flexibility in the pre-elderly and elderly. It was is quasi-experimental study with a pre-experimental one-group pretest-posttest research design. A total of 20 participants were selected using consecutive sampling according to the inclusion criteria. Flexibility measurements of the upper and lower limbs were carried out before and after the intervention using the back scratch test and chair sit and reach test methods. Surya  Namaskar intervention was carried out for 8 wk. Data were analyzed using the Shapiro-Wilk normality test, paired t-test, and Wilcoxon test. The results showed that there was a highly significant difference between the mean value of the back-scratch test (for upper limb flexibility) before and after the intervention (p<0.001). Significant differences were also found in the mean values of chair-sit-and-reach test measurements (for lower extremity flexibility) before and after the intervention (p<0.001). In conclusion, Surya  Namaskar exercises can improve the flexibility of the upper and lower extremities in the pre-elderly and elderly. 
SYSTEMATIC ANALYSIS ON HOW ASANA AND PRANAYAMA YOGA AFFECTS STRESS LEVELS IN MEDICAL STUDENTS Putri, Nabila Adithya; Prastowo, Nawanto Agung; Suryani, Eva; Amita, Angela Shinta Dewi
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 12, No 4 (2023): Desember
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.86054

Abstract

Background: Medical students are susceptible to mental illnesses that are brought on by expectations for exceeding academic success. To avoid more serious risks in the future, medical students must manage their stress because it contributes to anxiety, depression, sleep issues, and decreased academic success. Regular yoga practice is one effective and efficient lifestyle modification that can be used to handle stress. This systematic review shows how yoga can help medical students feel less stressed. This study aims to determine the effect between the duration and frequency of Asana and Pranayama Yoga on stress levels in medical students.Methods: Studies till 2022 are used in this systematic review. Articles were accumulated using PubMed, ProQuest, and EBSCOhost. Each search engine has its own designated keywords. Studies were assessed using the NHLBI Study Quality Assessment Tools. Ten studies met the criteria for this study and were all used and analyzed.  Results: There were ten studies that met this systematic review criteria and were rated as having good quality by the NHLBI quality assessment tool. All studies showed an association between the frequency of yoga sessions and reduced stress in medical students. Some studies had shorter yoga sessions than others, so the duration of each session did not affect the results as much as the frequency.  Conclusion: This study shows that the frequency of yoga sessions has an impact, resulting in lower stress levels in medical students. The impact of yoga duration is minimal when compared to yoga frequency. Yoga should be applied as an intervention to increase the quality of life of medical students. 
HUBUNGAN DERAJAT MIOPISASI DENGAN KATARAK SENILIS TIPE NUKLEAR PADA PASIEN POLI KLINIK MATA RUMAH SAKIT ATMA JAYA JAKARTA TAHUN 2018-2023 Tjan, Vania Nirmala; Amita, Angela Shinta Dewi; Kuswidyati, Cisca; Margareta, Evi Ulina; Dewi, Rita
Bahasa Indonesia Vol 23 No 3 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i3.5048

Abstract

Pendahuluan: Katarak adalah penyebab utama gangguan penglihatan, memengaruhi jutaan orang di seluruh dunia, termasuk 81% kasus kebutaan di Indonesia, terutama katarak senilis. Miopia, yang sering dikaitkan dengan katarak nuklear, terjadi akibat perubahan indeks bias pada lensa mata yang mengakibatkan "myopic shift" atau miopisasi. Miopisasi dapat memberikan ilusi perbaikan penglihatan dekat ("second-sight"), yang sering menunda diagnosis dan perawatan katarak. Penelitian ini bertujuan untuk mengetahui insidensi dan derajat miopisasi pada pasien katarak senilis di klinik mata Rumah Sakit Atma Jaya (RSAJ), Jakarta. Metode: Penelitian analitik dengan metode potong lintang retrospektif pada 92 sampel mata pasien di klinik mata RSAJ. Pengumpulan data dilakukan melalui rekam medis pasien yang terdiagnosis katarak senilis tipe nuklear dan mengalami miopisasi. Pengambilan data rekam medis dilakukan di RSAJ pada bulan April 2023 – Juli 2023 kemudian dilanjutkan pengolahan data dengan uji Chi-square. Hasil: Penelitian ini menunjukkan insidensi miopisasi pada katarak senilis berjenis nuklear dengan derajat NO3-NO6 sebesar 39,1% dengan derajat miopia ringan terbanyak yaitu 88,1% dan terdapat hubungan bermakna antara derajat miopisasi ringan dengan katarak senilis tipe nuklear (p=<0,001). Hasil analisis data juga menunjukkan tidak terdapat hubungan antara derajat miopisasi sedang dengan katarak senilis tipe nuklear (p=0,056). Simpulan: Penelitian ini menunjukkan adanya hubungan antara derajat miopisasi ringan dan sedang dengan katarak senilis tipe nuklear pada pasien di klinik mata RSAJ.