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Funduskopi untuk Prognosis Preeklampsia Iskandara, Ferdy; Djunaedia, Laura Agnestasia; Amitab, Angela Shinta Dewi; Diptoadic, Sigit Pradono
Cermin Dunia Kedokteran Vol 45, No 3 (2018): Muskuloskeletal
Publisher : PT. Kalbe Farma Tbk.

Hipertensi dalam kehamilan (HDK) merupakan masalah kesehatan yang perlu mendapat perhatian karena mengakibatkan lebih dari 25% kematian ibu di Indonesia pada tahun 2013. Pada preeklampsia â€“ yang merupakan salah satu HDK â€“ terjadi disfungsi endotel berbagai organ ibu hamil, termasuk organ mata. Konsekuensi tersering adalah vasospasme umum disertai kebocoran plasma yang menyebabkan iskemi retina hingga kerusakan visus permanen. Derajat kelainan retina ibu hamil berdasarkan klasifikasi Keith-Wagener-Barker berbanding lurus dengan angka kematian serta angka kecacatan penglihatan. Funduskopi sebagai salah satu sarana pelengkap dapat menjadi sarana objektif memperkirakan prognosis ibu hamil dan juga status janin.

Sudden Onset of Strabismus in Adults-Is It a Life-Threatening Sign? Dewi Amita, Angela Shinta; Faustine, Giovani
Cermin Dunia Kedokteran Vol 48, No 9 (2021): Nyeri Neuropatik
Publisher : PT. Kalbe Farma Tbk.

The overall incidence of strabismus is higher in adults; approximately 1% of children have strabismus, while the estimation among adults is 4% but may run as high as 5.6%. The four types of new-onset strabismus in adults most often found were paralytic, convergence insufficiency, small-angle hypertropia, and divergence insufficiency. The stroke should be suspected in the sudden onset of paralytic strabismus. The most prevalent type of manifest strabismus found on stroke survivors was exotropia. Tumors, myasthenia gravis, thyroid eye disease are common causes of gradual-onset strabismus. Thorough examinations and proper referral are needed.Insidens rata-rata strabismus lebih tinggi pada dewasa; sekitar 1% populasi anak mengalami strabismus, sedangkan perkiraan prevalensi strabismus dewasa sebesar 4%, dan dapat mencapai 5,6%. Empat tipe strabismus onset baru pada dewasa yang paling sering adalah paralitik, insufisiensi konvergen, hipertropia sudut kecil, dan insufisiensi divergen. Salah satu penyebab paralitik yang harus diwaspadai adalah stroke. Eksotropia merupakan tipe strabismus yang paling sering pada pasien post-stroke. Tumor, miastenia gravis, penyakit tiroid pada mata merupakan penyebab umum kasus strabismus onset lambat. Pemeriksaan menyeluruh dan sistem rujukan yang baik diperlukan untuk terapi yang memuaskan.

Retinopati Klorokuin dan Hidroksiklorokuin Alberta, Ivana Beatrice; Tri Ekaputri, Maria Vania; Amita, Angela Shinta Dewi
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Klorokuin dan hidroksiklorokuin kerap digunakan sebagai tatalaksana berbagai penyakit autoimun, infeksi malaria, dan kini menjadi salah satu obat penanggulangan darurat Coronavirus Disease-19 (COVID-19). Kedua obat ini berpotensi sebagai antiinflamasi dan antivirus. Namun penggunaannya sering menimbulkan berbagai efek samping seperti pada jantung, saraf, saluran pencernaan, dan juga mata. Efek samping pada mata dapat berupa toksisitas retina yang dapat berakhir menjadi retinopati ireversibel. Guna menghindari cacat permanen, diperlukan pencegahan yang tepat dengan mengenali faktor risiko dan skrining, serta pemantauan ketat penggunaan obat.Chloroquine and hydroxychloroquine are often used as a treatment for autoimmune disease, malaria infection, and now become an emergency drug for Coronavirus Disease-19 (COVID-19). Both are potential anti-inflammatory and antiviral agents. However, potential various side effects to the heart, nerves, gastrointestinal tract, and also eyes must be considered. Side effects on the eyes are retinal toxicity which can end up as irreversible retinopathy. Proper prevention is needed by recognizing risk factors and screening, as well as strict monitoring of drug use.

Modalitas Pencegahan Progresivitas School-age Myopia -, Angelo; Shinta, Angela; Halim, Andrew Adiguna
Cermin Dunia Kedokteran Vol 44, No 4 (2017): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Miopia merupakan salah satu masalah kesehatan dunia. Banyak peneliti menyimpulkan bahwa progresivitas miopia pada anak usia sekolah terjadi melalui proses form deprivation myopia(FDM). Bukti-bukti penelitian menunjukkan bahwa miopia lebih diakibatkan oleh faktor-faktor lingkungan dibandingkan faktor genetik. Penggunaan kacamata, lensa kontak, ortho-k maupun farmakologis dapat mengurangi perkembangan FDM. Terapi farmakologis menggunakan atropin merupakan cara terbaik menghambat FDM meskipun memiliki sejumlah efek samping.Miopia is one of the worldâ€™s greatest health problems. Many researchers concluded that the progression of school-age myopia happens through form deprivation myopia. Due to the fact that myopia is caused more by environmental factors rather than genetic factors, researchers are trying to find the best prevention modalities. Spectacles, contact lens, ortho-k or pharmacologic approach are the modalities to halt the progression of FDM. Atropine can be the best modalities to prevent FDM despite its side effects.

KOMORBIDITAS PADA EPISODE REKUREN SINDROM POSNER-SCHLOSSMAN DAN NEUROPATI OPTIK KARENA ETAMBUTOL Angela Shinta Dewi Amita; Kristian Dernitra; Thendy Foraldy
Bahasa Indonesia Vol 19 No 2 (2020): Damianus : Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v19i2.1781

Introduction: Posner-Schlossman Syndrome (PSS) or glaucomatocyclitic crisis is a rare ophthalmic disease characterized by unilateral, acute, and recurrent attacks of elevated intraocular pressure (IOP) accompanied by mild anterior chamber inflammation without any conclusive causative factor. This case report represents a concurrence of Ethambutol-induced Optic Neuropathy (EON) and recurrent episode of PSS. Although this combination rarely occurs, but it can significantly affect the prognosis of both conditions.Case: A 41-year-old woman with unilateral ocular pain and blurred vision for the last 24 hours presented with left anterior uveitis, elevated intraocular pressure 56.7 mmHg and was diagnosed with left eye PSS. Five years later she showed signs of bilateral EON after 5 months of ethambutol administration as tuberculosis treatment. Best Corrected Visual Acuity (BCVA) was (20/80 OD, 20/70 OS), with an unspecified bilateral cecocentral scotomas. After 1 month of ethambutol cessation, the patient had a recurrent episode of PSS on the left eye and worsening the visual acuity more on both eyes (20/400 OD, 20/200 OS). The patient was then treated with methylprednisolone injection, and the visual acuity starts to improve (20/100 ODS).Conclusion: Comprehensive examination to detect probable etiologies of PSS is important to prevent recurrences and possible comorbidities with other eye disease, such as EON in this case. Patients undergoing ethambutol medication should be assessed by an ophthalmologist before, during and after finished treatment to evaluate the patient’s risk factors, past medical history and progression of visual acuity during treatment.

Determination on the Success of Cataract Surgeries by Using Sight Restoration Rate (SRR) Angelo Doniho; Angela Shinta Dewi Amita; Cisca Kuswidyati; Devina Permatasari; Andrew Adiguna Halim
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 5, No 1 (2019): April
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

The prevalence of blindness in Nusa Tenggara Timur (NTT) reaches 1.0% and the ratio of blindness to ophthalmologist reaches 1:8000. This data means NTT is a place which has vision issues. Blindness is caused by cataract. Untreated cataracts can reduce the productivity of patients and his/her caretaker for quite a long time. Cataract surgery will not only cure the patient’s blindness, but it will also improve the local economy if it is sustainable and on time. Lack of human resources, funds, and medical equipment are the major problems for performing cataract surgery in this area. The cataract surgery is performed at Elisabeth Lela Hospital. Visual acuity is performed before the surgery and 21-35 days after the surgery. The last step is calculating the Sight Restoration Rate (SRR) of all patients. Cataract surgery was conducted to 92 eyes. the SRR of all patients is 46.7%. There are four eyes (4.34%) with post-operative visual acuity <3/60.

Association between Refractive Error Types and Asthenopia in Primary School Students Vanessa Kuswanto; Felicia Kurniawan; Angela Shinta Dewi Amita
Majalah Kedokteran Bandung Vol 53, No 3 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v53n3.2236

Refractive error is a condition in which the cornea and lens fail to focus the light, resulting in reduced visual efficiency. Twelve million children are experiencing refractive errors worldwide and uncorrected refractive errors in children have been reported to cause asthenopia. This study aimed to determine the association between the types of refractive errors and asthenopia in children. This cross-sectional study was conducted on 111 students aged 10-13 years old in a public elementary school in Indonesia, SDN Penjaringan 10, in 2019. A questionnaire was used to assess asthenopia and the Snellen Chart, trial frames, and trial lenses were used for refractive errors examination. It was demonstrated that 87.4% of respondents experienced asthenopia, and 53.2% of respondents suffered from uncorrected refractive errors, mostly due to myopia. Fisher’s exact test results showed an association between refractive errors and asthenopia (p=0.019) with all myopic students experienced asthenopia. However, there was no significant association between astigmatism and asthenopia (p=0.754). In conclusion, not all types of refractive errors are associated with asthenopia.

Retinopati Klorokuin dan Hidroksiklorokuin Ivana Beatrice Alberta; Maria Vania Tri Ekaputri; Angela Shinta Dewi Amita
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i10.1081

Klorokuin dan hidroksiklorokuin kerap digunakan sebagai tatalaksana berbagai penyakit autoimun, infeksi malaria, dan kini menjadi salah satu obat penanggulangan darurat Coronavirus Disease-19 (COVID-19). Kedua obat ini berpotensi sebagai antiinflamasi dan antivirus. Namun penggunaannya sering menimbulkan berbagai efek samping seperti pada jantung, saraf, saluran pencernaan, dan juga mata. Efek samping pada mata dapat berupa toksisitas retina yang dapat berakhir menjadi retinopati ireversibel. Guna menghindari cacat permanen, diperlukan pencegahan yang tepat dengan mengenali faktor risiko dan skrining, serta pemantauan ketat penggunaan obat.Chloroquine and hydroxychloroquine are often used as a treatment for autoimmune disease, malaria infection, and now become an emergency drug for Coronavirus Disease-19 (COVID-19). Both are potential anti-inflammatory and antiviral agents. However, potential various side effects to the heart, nerves, gastrointestinal tract, and also eyes must be considered. Side effects on the eyes are retinal toxicity which can end up as irreversible retinopathy. Proper prevention is needed by recognizing risk factors and screening, as well as strict monitoring of drug use.

Sudden Onset of Strabismus in Adults-Is It a Life-Threatening Sign? Angela Shinta Dewi Amita; Giovani Faustine
Cermin Dunia Kedokteran Vol 48, No 9 (2021): Nyeri Neuropatik
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v48i9.1495

The overall incidence of strabismus is higher in adults; approximately 1% of children have strabismus, while the estimation among adults is 4% but may run as high as 5.6%. The four types of new-onset strabismus in adults most often found were paralytic, convergence insufficiency, small-angle hypertropia, and divergence insufficiency. The stroke should be suspected in the sudden onset of paralytic strabismus. The most prevalent type of manifest strabismus found on stroke survivors was exotropia. Tumors, myasthenia gravis, thyroid eye disease are common causes of gradual-onset strabismus. Thorough examinations and proper referral are needed.Insidens rata-rata strabismus lebih tinggi pada dewasa; sekitar 1% populasi anak mengalami strabismus, sedangkan perkiraan prevalensi strabismus dewasa sebesar 4%, dan dapat mencapai 5,6%. Empat tipe strabismus onset baru pada dewasa yang paling sering adalah paralitik, insufisiensi konvergen, hipertropia sudut kecil, dan insufisiensi divergen. Salah satu penyebab paralitik yang harus diwaspadai adalah stroke. Eksotropia merupakan tipe strabismus yang paling sering pada pasien post-stroke. Tumor, miastenia gravis, penyakit tiroid pada mata merupakan penyebab umum kasus strabismus onset lambat. Pemeriksaan menyeluruh dan sistem rujukan yang baik diperlukan untuk terapi yang memuaskan.

Funduskopi untuk Prognosis Preeklampsia Ferdy Iskandara; Laura Agnestasia Djunaedia; Angela Shinta Dewi Amitab; Sigit Pradono Diptoadic
Cermin Dunia Kedokteran Vol 45, No 3 (2018): Muskuloskeletal
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i3.188

Hipertensi dalam kehamilan (HDK) merupakan masalah kesehatan yang perlu mendapat perhatian karena mengakibatkan lebih dari 25% kematian ibu di Indonesia pada tahun 2013. Pada preeklampsia – yang merupakan salah satu HDK – terjadi disfungsi endotel berbagai organ ibu hamil, termasuk organ mata. Konsekuensi tersering adalah vasospasme umum disertai kebocoran plasma yang menyebabkan iskemi retina hingga kerusakan visus permanen. Derajat kelainan retina ibu hamil berdasarkan klasifikasi Keith-Wagener-Barker berbanding lurus dengan angka kematian serta angka kecacatan penglihatan. Funduskopi sebagai salah satu sarana pelengkap dapat menjadi sarana objektif memperkirakan prognosis ibu hamil dan juga status janin.

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