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Association Of Gestational Age And Birth Weight With Neonatal Sepsis In Ulin Hospital Banjarmasin Andayani, Pudji; Salim, Monica Anggriana; Halim, Pricilia Gunawan; Yunanto, Ari
Berkala Kedokteran Vol 19, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i2.17385

Indonesia is ranked 7th in the country with the highest neonatal mortality rate in the world, respectively 60.000 neonatal deaths per year. Neonatal sepsis in one of the major causes of neonatal death. The aim of this study is to find the association of gestational age and birth weight with the incidence of neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021. This study is a retrospective study with a cross sectional approach at Neonatal Ward, Ulin Hospital Banjarmasin, South Borneo, January to December 2021. The total sample was 200 infants consisting of 100 healthy infants and 100 sepsis infants. The source of gestational age, birth weight, and diagnosis data were taken through patient medical records. The mean gestational age of healthy infant group was 38,45 weeks (all infants were at term) while in septic infant group was 33,59 weeks (70%preterm, 28%at-term, and 2%post-term). The average birth weight of healthy infant group was 3021.24 grams (all infants were normal birth weight) while in septic infant group was 2003,59 grams (25%normal birth weight, 40%low birth weight, 25%very low birth weight, and 10%extremely low birth weight). There were an association of gestational age and birth weight with neonatal sepsis, confidential rate was 95%. (p<0,000 and p<0,000). There were an association of gestational age and birth weight with neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021.

Clinical Characteristics and Outcomes of Neonatal Sepsis due to Pseudomonas putida in South Kalimantan Andayani, Pudji; Hartoyo, Edi; Pasaribu, Munawaroh; Marhaeni, Wulandewi; Yunanto, Ari; Putra, Nataniel Hadi; Himawan, Gratianus Billy; Salim, Monica Anggriana; Halim, Pricilia Gunawan
Jurnal Kedokteran Brawijaya Vol. 34 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2026.034.01.4

Pseudomonas putida is a Gram-negative bacterium that can cause nosocomial infections, particularly in neonates. This study aimed to identify the characteristics of neonates with P. putida infection, the antibiotics administered, and the treatment outcomes during a P. putida outbreak. This descriptive study collected data from the medical records of neonates diagnosed with neonatal sepsis admitted to Ulin Hospital, Banjarmasin, between August and October 2022. Data collected included patient characteristics, clinical profiles, laboratory results, antibiotic therapy, P. putida antibiotic sensitivity results, and bacterial culture results from samples taken in the NICU during the outbreak period. Fourteen neonates (6.5%) had positive P. putida during the outbreak of blood cultures, including 13 neonates born at Ulin Hospital and one referred from another health facility. Neonates with P. putida infection exhibited leukopenia, thrombocytopenia, and elevated CRP levels. After obtaining the culture results and antibiotic sensitivity tests, the choice of antibiotics was adjusted based on the bacteria's sensitivity. The antibiotics found compelling during treatment included ciprofloxacin, cefepime, tazobactam, gentamicin, a combination of ciprofloxacin and amikacin, and a combination of piperacillin. Most of the clinical and laboratory characteristics improved following treatment, but three neonates unfortunately died during hospitalization. Overall, there were clinical and laboratory improvements after administering antibiotics according to the culture-based antibiotic resistance results.

The Relationship between APGAR Score and Delivery Mode with Neonatal Sepsis in Ulin Regional Hospital Banjarmasin Salim, Monica Anggriana; Halim, Pricilia Gunawan; Yunanto, Ari; Andayani, Pudji
Jurnal Kedokteran Brawijaya Vol. 32 No. 4 (2023)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2023.032.04.4

Neonatal sepsis is one of the most common causes of neonatal death worldwide, affecting up to 3 million neonates each year. Deaths related to neonatal sepsis are more common in developing countries with lower middle incomes. This study aims to find a relationship between APGAR scores at the 1st, 5th, and 10th minutes and delivery mode on the incidence of neonatal sepsis. This research is a retrospective study with a cross-sectional approach at High-Risk Neonatal Installation (INRiT) of Ulin Regional Hospital Banjarmasin, South Kalimantan, conducted from January to December 2022. The total sample was 200 babies divided into the sepsis and the control group. APGAR score data at the 1st, 5th, and 10th minutes and delivery mode were taken through medical records. In this study, the average APGAR score at 1st minute in the sepsis group was 5.11; at 5th minute was 6.56; and at 10th minute was 7.65. The results of APGAR score analysis at the 1st, 5th, and 10th minutes in the sepsis and control groups using the Mann -Whitney test obtained a p-value of 0.000. In the sepsis group, 30 babies were born spontaneously, and 70 babies were born with tools (caesarean section/vacuum extraction). The results of the delivery mode analysis in the sepsis and control groups using Fisher's test obtained a p-value of 0.000 (OR: 3.807) which means that there is a relationship between the APGAR score at the 1st, 5th, and 10th minutes and the delivery mode with the incidence of neonatal sepsis.

Clinical Characteristics and Outcomes of Neonatal Sepsis due to Pseudomonas putida in South Kalimantan Andayani, Pudji; Hartoyo, Edi; Pasaribu, Munawaroh; Marhaeni, Wulandewi; Yunanto, Ari; Putra, Nataniel Hadi; Himawan, Gratianus Billy; Salim, Monica Anggriana; Halim, Pricilia Gunawan
Jurnal Kedokteran Brawijaya Vol. 34 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2026.034.01.4

Pseudomonas putida is a Gram-negative bacterium that can cause nosocomial infections, particularly in neonates. This study aimed to identify the characteristics of neonates with P. putida infection, the antibiotics administered, and the treatment outcomes during a P. putida outbreak. This descriptive study collected data from the medical records of neonates diagnosed with neonatal sepsis admitted to Ulin Hospital, Banjarmasin, between August and October 2022. Data collected included patient characteristics, clinical profiles, laboratory results, antibiotic therapy, P. putida antibiotic sensitivity results, and bacterial culture results from samples taken in the NICU during the outbreak period. Fourteen neonates (6.5%) had positive P. putida during the outbreak of blood cultures, including 13 neonates born at Ulin Hospital and one referred from another health facility. Neonates with P. putida infection exhibited leukopenia, thrombocytopenia, and elevated CRP levels. After obtaining the culture results and antibiotic sensitivity tests, the choice of antibiotics was adjusted based on the bacteria's sensitivity. The antibiotics found compelling during treatment included ciprofloxacin, cefepime, tazobactam, gentamicin, a combination of ciprofloxacin and amikacin, and a combination of piperacillin. Most of the clinical and laboratory characteristics improved following treatment, but three neonates unfortunately died during hospitalization. Overall, there were clinical and laboratory improvements after administering antibiotics according to the culture-based antibiotic resistance results.

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