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All Journal e-Journal Pustaka Kesehatan Dentika Dental Journal STOMATOGNATIC- Jurnal Kedokteran Gigi Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dental Researchers and Students Jurnal Abdi Masyarakat (JAM) Denta: Jurnal Kedokteran Gigi Dental Agromedis
Muhammad Nurul Amin
Fakultas Kedokteran Gigi, Universitas Jember (UNEJ) Jln. Kalimantan 37, Jember 68121
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Medicine & Pharmacology Public Health

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Journal : e-Journal Pustaka Kesehatan

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Potensi Rebusan Kulit Buah Manggis Alami (Garcinia mangostana Linn) untuk Meningkatkan Aktivitas Mikrobisida Sel Neutrofil terhadap Streptococcus mutans (The Potency of Mangosteen Peel Infution (Garcinia mangostana L.) to Increase Neutrophil Microbicidal Athiyah Naila Sakinah; Muhammad Nurul Amin; Purwanto .
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Neutrophils were part of leucocyte cells which dominate in blood circulation. When the microorganism entered the body, neutrophils kill it immediately. The steps that were migration, ingestion, swallowing, and microbicidal activity or intercellular killing. The contents of mangosteen peel is presumed to help neutrophils beat bacteria. Samples numbered 28 consist of 7 treatment groups, namely K 1 (negative control), K II (positive control), K III 100% MPI (Mangosteen Peel Infution), K IV 75% MPI, K V 50% MPI, K VI 25% MPI, and K VII 100% MPIwithout neutrophils. Isolated neutrophils exposed to MPI appropriate treatments groups above and then incubated for 3 hours. Subsequently exposed to S. mutans and incubated again for 3 hours. After that, the sample werecultured in BHI-A media and incubated for 1x24 hours. Furthermore, bacterial colonies were counted with a colony counter method. The result showed a significant difference between MPI treatment groups with control groups. The conclusion of this research is thenatural mangosteen peel infution hasthe potential to increase microbicidal activity of neutrophils and can act as an antibacterial.   Keywords: mangosteen (Garcinia mangostana L.),microbicidal,neutrophils, S. mutans.
Pengaruh Ekstrak Daun Pepaya Terhadap Jumlah Sel Limfosit Pada Gingiva Tikus Wistar Jantan Yang Mengalami Periodontitis (The effect of papaya leaves extract to the number of lymphocytes cells to the male-wistar rat's gingiva that undergo periodontitis) Utama Bramanto Satrya Dimas; Yuliana Mahdiyah Da’at Arina; Muhammad Nurul Amin
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Background. Porphyromonas gingivalis (P. gingivalis) is plaque bacteria caused periodontitis with proteolitic characterised that makes some damages to the periodontal tissues. Lymphocytes are chronic inflamed cells which have specific characteristic when periodontitis was occured. Papaya is known as herbal plants, which contains substances which have antimicroba and antiinflamation activities in its leaves. The purpose of this research is to determinate the effect of papaya leaves extract to the number of limfocyte cells to the male-wistar rats gingival that was periodontitis. Twenty male-wistar rats that were divided to the five groups with different treatments. The first group is control of other group, the second group is treatment group that was induced with P. gingivalis and assembled with a ligature, while the remaining of groups were added with the extract of papaya leaves sondation by certain concentration 25% for the third group, 50% for the fourth group, and 75% for the last group after getting some treatments as the second group. The result of the research showed that the highest lymphocytes cells was found to group that was induced by P. gingivalis and assembled with a ligature. In the contrary, the lowest lymphocytes cells was found to the fifth group that was treated with the extract of papaya leaves 75%. It concluded that papaya leaves extract decreased the number of lymphocytes in periodontitis male-wistar rats gingival. The most effectively of papaya leaves extract that was used is 75%. Advanced research about the compound of the extract of papaya leaves which most influential and the mechanism to the decrease of the number of lymphocytes cells are needed. Keywords: Papaya Leaves Extract, Periodontitis, P. gingivalis
Co-Authors Agustin Wulan Suci Dharmayanti Amiyatun Naini Annisa Furqoni Athiyah Naila Sakinah Banun Kusumawardani Budi Yuwono Budi Yuwono Budi Yuwono Clarissa Astiasari Desi Sandra Sari Desi Sandrasari Devi Komala Dewi Sulistianingsih Giarningtyas, Naufalia I Dewa Ayu Ratna Dewanti Kumala, Efa Ayu Ratnaning Mei Syafriadi Nafi, Zidna Ilma Nanda Afnita Nur Permatasari Nurud Diniyah Purnama, Galuh Putri Purwanto . Rendra Chriestedy Prasetya Roedy Budirahardjo Septiana Dwi Rahayu Sumono, Agus Tecky Indriana Utama Bramanto Satrya Dimas Winny Adriatmoko Yani Corvianindya Rahayu Yuliana Mahdiyah Daat Arina Zahara Meilawaty