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All Journal Majalah Ilmiah Sultan Agung Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Odonto dental journal Yarsi Dental Journal
Musri Amurwaningsih
Department Of Public Dental Health Faculty Of Dentistry Sultan Agung Islamic University
Dentistry Education Health Professions Medicine & Pharmacology Public Health

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Journal : odonto dental journal

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PERBEDAAN EFEKTIFITAS EKSTRAK TEMULAWAK (Curcuma Xanthorrizae Roxb) DENGAN BERBAGAI KONSENTRASI TERHADAP PERTUMBUHAN CANDIDA ALBICANS PADA PLAT RESIN AKRILIK KURING PANAS - In Vitro Inanda Nita; Musri Amurwaningsih; Uswatun N.A. Darjono
ODONTO : Dental Journal Vol 1, No 1 (2014): July 2014
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.1.1.20-24

Abstract

Background: Temulawak (curcuma xanthorrizae roxb) contains many substance such as xanthorrizol, curcumin, essential oil, flavonoid. Essential oil and flavonoid works by damaging the cell wall and protein denaturation can inhibits the growth of the fungi Candida albicans attached to the surface of the heat cured acrylic resin plate. The purpose of this study is to determine the extract Temulawak effect on the growth of Candida albicans at heat cured acrylic resin plate. Method : The Eksperiment is true experimental laboratories with post test only controlled group design. 10x10x2 mm Acrylic resin plate was soaked into Candida albicans suspension for 48 hours at 37o then soaked in curcuma xanthorrizae roxb extract 90%, 80%, 70%, 60%, control group positive (chlorhexidine 0,2%), control negatif (water) for 8 hours at 37o. Result: The result of the experiment showed that control group (-)has the highest value (839,20 x 101 CFU/ml), while the least was 90% ekstract of curcuma xanthorrizae roxb group (23,40 x 101 CFU/ml). After normality and homogenity test was done, One Way Anova test was executed (p = 0,000. means p < 0,05). Conclussion: extract Temulawak can inhibit Candida albicans growth on heat cured acrylic resin.
BAY LEAF (SYZYGIUM POLYANTHUM) EXTRACT GEL EFFECT ON TNF- Α EXPRESSION IN TRAUMATIC ULCERS HEALING PROCESS Savira, Annisha; Mujayanto, Rochman; Amurwaningsih, Musri
Odonto : Dental Journal Vol 7, No 1 (2020): July 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.7.1.25-30

Abstract

Background: Traumatic ulcers were injuries that occur to the epithelium and basement membrane, due to physical, mechanical, or chemical trauma. The healing process of traumatic ulcers was divided into three main phases, namely inflammatory, proliferation, and maturation phase. TNF-α as a proinflammatory mediator worked 2-3 days which later would be replaced by an anti-inflammatory mediator. This research aimed to determine the impact of bay leaf extract gel, which had a very high anti-inflammatory content, on TNF-α expression in accelerating the ulcers healing process.Method: This research method was an in vivo experimental laboratory research using a post-test only control design. The sample consists of 20 rats divided into four groups, namely, the control group on day 1, control groups on day 3, treatment groups on 1st day, and treatment groups on 3rd day. Rats were made traumatic ulcers on the lower lip mucosa and were given bay leaf extract gel in the morning and evening. The tissue was then made into a histological preparation and given immunohistochemical staining to see TNF-α.Result: The results showed the mean of cells expressing TNF-α in the bay leaf gel extract group on the 1st and 3rd days has P> 0.05. Independent T-test on 1st day dan 3rd group showed a significant difference in TNF-α expression in the control and treatment groups.Conclusion: The conclusion obtained in this study was bay leaf extract gel had a significant effect on the expression of TNF-α in the traumatic ulcers healing process.
Co-Authors Afaf Afaf Amalia, Khofifah An Nafsi, Zidni Zakiah Anha Rizza Muzenin Asri Atyanta Benni Benyamin Benni Benyamin Dea Sutami Dini, Nabilah Nur Erna Dwi Agustin Erna Dwi Agustin, Erna Dwi Farichah Hanum Fatimah Alaydrus Gani, Lutfiah Karenina Ika Dewi Ana Inanda Nita Nira Ardlina Prasetya, Denta Aditya Prima Agusmawanti, Prima Putri Apriliyana Wahyuningsih Putri, Salsabila Awalia Rina Kartika Sari Rochman Mujayanto Savira, Annisha Shafia, Arina Sunnah, Tahta Danifatis Titi Savitri Prihatiningsih Uswatun N.A. Darjono Uswatun Nisaa’ Arum Darjono Uswatun Nisaa’ Arum Darjono Welly Anggarani Wirda Yunita Darwis Yayun Siti Rochmah