Hansen Angkasa
Medical Science Program, Faculty of Medicine Universitas Indonesia, Jakarta

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Opioid-Free Anesthesia in Ophthalmic Surgeries Tantri, Aida Rosita; Angkasa, Hansen; Firdaus, Riyadh; Claudia, Tasya; Tantri, Ignatia Novianti
Indonesian Journal of Anesthesiology and Reanimation Vol. 5 No. 2 (2023): Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Publisher : Faculty of Medicine-Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijar.V5I22023.81-87

Abstract

Introduction: Opioid-free anesthesia (OFA) is an alternative to Opioid based anesthesia (OBA) which uses multimodal analgesia to replace opioids. However, its feasibility, safety, and exact recommended combination remain debatable. Case Series: We administered OFA in 5 types of elective ophthalmic surgeries under general anesthesia in ASA 1-2 adult patients (evisceration, ocular exenteration, periosteal graft, scleral buckling, vitrectomy, and dacryocystorhinostomy) to assess the feasibility of OFA. We gave preoperative Paracetamol and Pregabalin with Dexmedetomidine as a loading dose (1 mcg/kg in 10 minutes) and maintenance at 0.7 mcg kg-1 per hour. Induction was performed using Propofol 1-2 mg kg-1, Lidocaine 1-1.5 mg kg-1 IV, and Rocuronium. Before the incision, Dexamethasone and Ranitidine were given. Maintenance was done using Dexmedetomidine and Sevoflurane. Fentanyl was used as rescue analgesia if required. Dexmedetomidine was stopped 15-30 minutes before the procedure ended. Metoclopramide and Ketorolac were given as postoperative management. Throughout the procedure, our patients had stable hemodynamics, did not experience life-threatening bradycardia, and did not require rescue analgesia. All patients regained full consciousness and did not experience postoperative nausea and vomiting, emergency delirium, or coughing. Conclusion: Multimodal analgesia was an excellent intraoperative OFA regimen as an alternative to OBA and provided controlled hypotension in ocular surgery. Safe OFA is possible with combined analgesia regimens, strict intraoperative monitoring, and adequate anesthesia depth.
Control of Scabies in a Boarding School Using 5% Permethrin Applied on Lesion Only Sungkar, Saleha; Wahdini, Sri; Kekalih, Aria; Rilanda, Risa; Angkasa, Hansen; Widaty, Sandra
ASEAN Journal of Community Engagement Vol. 6, No. 1
Publisher : UI Scholars Hub

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Abstract

Scabies is one of the most neglected tropical skin diseases in Indonesia. It is usually found in overcrowded communities with poor hygiene. The gold standard for scabies treatment is the whole-body topical application of 5% permethrin cream. However, the treatment causes inconvenience and stickiness for a prolonged period. The modification of topical treatment by applying only to the lesion yielded results similar with whole-body topical application. We consider using this mode of treatment to control the disease in a boarding school. The study was conducted from June to August 2019. All students were examined by dermatologists, and individuals who were diagnosed with scabies were treated using 5% permethrin for 12 h before wash-off (week 0) applied on the lesion only and reapplied a week after. The evaluation was conducted on weeks 4 and 8 by observing scabies lesions. Local health cadres were also trained, and environmental interventions were also performed. A total of 75 participants were analyzed. Most lesions were found on predilection sites such as finger web spaces of the left (57.3%) and right (58.7%) hands, gluteal region (60%), and penis (40%). The cure rate (CR) was 83%–100% of the lesions in week 4, which increased to 95%–100% in week 8. The CR on week 8 compared with baseline was 94.7% (p < 0.001). A total of 23 cadres were trained, and from post-test, 84% of the cadres showed good knowledge of scabies management. This novel application of 5% permethrin cream on the lesion only is an effective alternative to the conventional whole-body topical application.