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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Teknologi Indonesia Jurnal Integritas Serasan Sekundang
Yulia Anita
Research Center for Chemistry (RCC-Chem), Indonesian Institute of Sciences (LIPI), Kawasan PUSPIPTEK Serpong, Tangerang Selatan, Banten 15314
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Materials Science & Nanotechnology Physics Social Sciences

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SYNTHESES AND CYTOTOXICITY ASSAY OF ANALOGUES OF UK-3A, A NOVEL FROM Streptomyces sp. 517-02 Anita, Yulia; Hanafi, M.; Arifin, S.
Teknologi Indonesia Vol 36, No 3 (2013)
Publisher : LIPI Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/jti.v36i3.211

Abstract

UK-3A is a minor compound from the mycelium of Streptomyces sp.517-02 and had been isolated. It has IC50 38 ?g/mL against P388 Murine Leukemia cells. Products of UK-3A analogues were assigned the name A and B compounds. These compounds were prepared from L-serine methyl ester-HCl as starting material and synthesized by amidation and esterifi cation. The products were determined by TLC, FT-IR, MS and NMR instruments. Theoverall yield was compounds A 95.63% and B 87.10%. The in vitro anticancer activities of compounds A and B against the same Leukemia cells and found to have IC50 46.5?g/mL and 15.4?g/mL, respectively. The compound B exhibited higher inhibitory activity than UK-3A.
DAMPAK PANDEMI COVID-19 TERHADAP UMKM DI KABUPATEN MUARA ENIM Anita, Yulia; Damayanti, Ester Claudya; Marsa Saisan, Desfa Gempata; Fitriani, Yulia; Pratiwi, Anggraini Wulan; Fauzan, Efran; Royda
Jurnal Integritas Serasan Sekundang Vol 5 No 1 (2023): Jurnal Integritas Serasan Sekundang
Publisher : Badan Penelitian dan Pengembangan Daerah KabupatenMuara Enim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64987/jiss.v5i1.39

Abstract

Pandemi Covid-19 memberikan pelajaran mendalam bagi Usaha Mikro Kecil Menengah (UMKM) di Kabupaten Muara Enim. Dampak Covid-19 pada UMKM di Kabupaten Muara Enim tidak saja pada aspek keuangan tetapi juga aspek non-keuangan. Oleh karena itu, penelitian ini bertujuan untuk memberikan gambaran dampak pandemi Covid-19 terhadap UMKM di Kabupaten Muara Enim. Fokus wilayah kajian yaitu Kecamatan Muara Enim, Lawang Kidul dan Ujan Mas. Selain itu, penelitian ini diharapkan dapat menjadi referensi dalam pengambilan kebijakan pemerintah untuk penanganan dampak Covid–19 terhadap UMKM. Penelitian ini menggunakan pendekatan kualitatif dengan metode Indepth interview dan Focus Group Discussion (FGD) pada 36 UMKM. Teknik analisis meliputi analisis deskriptif dan analisis naratif. Hasil penelitian menujukkan bahwa Covid-19 berdampak pada penurunan permintaan dan daya beli masyarakat. Temuan juga membuktikan Pandemi covid-19 menurunkan jumlah pendapatan, keuantungan dan jumlah karyawan pada UMKM di Kabupaten Muara Enim. Sejumlah program pemulihan melalui kebijakan keringanan kredit, bantuan modal usaha, dan program keringanan lainnya untuk menstimulus UMKM yang terdampak Covid-19 selama pandemic telah diupayakan oleh pemerintah daerah. Adapun strategi yang dapat dilakukan pemerintah yaitu perluasan akses pasar, pengembangan kewirausahaan, akselerasi pembiayaan dan investasi, koordinasi lintas sector dan transformasi Ekonomi Digital.
Effectiveness of STEM-Based Project-Based Learning in Enhancing Senior High School Students’ Scientific Literacy Lubis, Ainun Mardiyah; Cholily, Yus Mochamad; Susetyarini, Rr. Eko; Purwanti, Elly; Anita, Yulia; Saputri, Nor Mita Ika; Elisa; Qoimah, Dikmatul
Jurnal Penelitian Pendidikan IPA Vol 12 No 1 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i1.14077

Abstract

The purpose of this study was to examine the effectiveness of the STEM (science, technology, engineering, and mathematics)-based Project-Based Learning (PjBL) model in improving senior high school students’ scientific literacy. This study employed a quasi-experimental method with a pre-test and post-test nonequivalent control group design and was conducted at SMA Negeri 5 Padangsidimpuan. The research involved two classes consisting of 35 students each: an experimental class taught using STEM-based PjBL and a control class taught using conventional learning. Scientific literacy was measured using an essay test, while students’ attitudes toward science were assessed through a questionnaire. The results of the independent samples t-test showed no significant difference in students’ initial abilities (sig. = 0.064 > 0.05). However, the post-test results indicated a significant difference between the two groups (sig. = 0.000 < 0.05), with the experimental class achieving a higher mean score. In addition, students’ attitudes toward science in the experimental class were categorized as good to very good. These findings indicate that STEM-based Project-Based Learning is effective in enhancing students’ scientific literacy.
Co-Authors Arifin, S. Damayanti, Ester Claudya Elisa Elly Purwanti Fauzan, Efran Lubis, Ainun Mardiyah M. Hanafi Marsa Saisan, Desfa Gempata Nor Mita Ika Saputri, Nor Mita Ika Pratiwi, Anggraini Wulan Qoimah, Dikmatul Royda Rr. Eko Susetyarini Yulia Fitriani, Yulia Yus Mochamad Cholily