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All Journal Universa Medicina Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Jurnal Biomedika dan Kesehatan eJournal Kedokteran Indonesia IJRETINA - International Journal of Retina Ophthalmologica Indonesiana Cermin Dunia Kedokteran
Estu Yulia, Dian
Department Of Ophthalmology, Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Leukokoria sebagai Tanda Peringatan Penyakit Coats dan Gangguan Retina Lainnya: Tinjauan Pustaka Paramita, Carennia; Yulia, Dian Estu
Cermin Dunia Kedokteran Vol 52 No 5 (2025): Kardiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i5.1581

Abstract

Coats’ disease is an idiopathic condition characterized by non-hereditary exudative retinopathy caused by abnormal retinal vascular development. Patients often present with signs such as leukocoria, significant vision loss, and strabismus. Some characteristic features include telangiectasia, aneurysms, and exudative retinal detachment. Ultrasonography and computed tomography scan can detect masses and calcifications, which are useful in ruling out differential diagnosis of retinoblastoma. Coats’ disease has 5 stages, but it is not uncommon for patients to seek treatment in advanced stages or when it has progressed to a malignancy in children, such as retinoblastoma, therefore the patient will be referred for enucleation.
Laporan Kasus Kekeruhan Kornea Kongenital: Tantangan Operasi Keratoplasti pada Anak-Anak : Laporan Kasus Yulia, Dian Estu; Pradiptama, Yura; Tan, Sabrina
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1712

Abstract

Introduction: Congenital corneal opacity (CCO) is a group of anterior segment dysgenesis of the eye manifested by corneal transparency loss at birth or during the first 4 weeks of life. CCO is one of the most prominent disease entities in anterior segment dysgenesis. CCO resulted from disruptions in mesodermal development, particularly affecting the anterior segment of the eye. Case:A 2-week-old boy with bilateral CCO. One week post-keratoplasty surgery, the parents reported no complaints but had difficulty administering eye drops. Physical examination showed a clearer corneal graft. One month later, a cloudy graft and broken sutures were noted, indicating graft rejection. The family was educated on the importance of consistent medication for any future graft surgery. Discussion: The surgical option for CCO is corneal graft or keratoplasty. Keratoplasty is a corneal transplant where a clear donor graft replaces the central opaque cornea. Conclusion: A comprehensive workup is essential for diagnosing CCO. Keratoplasty can restore corneal clarity and vision, but pediatric cases require careful patient education and comprehensive follow-up.
Co-Authors Aprina, Dwie Caroline, Christella Casey, Anthea Fedora, Ghina Hutapea, Mario Marbungaran Jayawinata, Marissa Julie Dewi Barliana Lia Amanda Paramita, Carennia Pertiwi, Adinda Mulya Pradiptama, Yura Pratiwi, Karina Satyani Putri, Meuthia Rana Sitorus, Rita Rita Sitorus, Rita Sita Soeharto, Diajeng Ayesha Soraya, Siti Halida Zoraida Tan, Sabrina Yeni Dwi Lestari Yulika Harniza Zahra, Raihanny Andrea