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Journal : Jurnal AFAMEDIS

POLA PERESEPAN OBAT ANTIDIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 DI POLI PENYAKIT DALAM RS “X” SIDOARJO PERIODE OKTOBER- DESEMBER 2019 Yugo Susanto; Sri Bangun Lestari; Elly Purwati
AFAMEDIS Vol. 1 No. 2 (2020): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Penelitian ini dilakukan untuk mengetahui pola peresepan obat antidiabetik pada pasien diabetes melitus tipe 2 di poli penyakit dalam RS “X” Sidoarjo periode Oktober-Desember 2019 sesuai dengan pedoman terapi ADA (American Diabetes Association) 2020. Penelitian ini dilakukan secara deskriptif yang bertujuan untuk menyajikan gambaran lengkap mengenai suatu keadaan secara objektif dengan metode total sampling dan pengambilan data secara retrospektif. Sampel dalam penelitian ini mengambil sejumlah 50 lembar resep yang masuk kriteria inklusi dan tercatat di pengumpul data meliputi nama obat, dosis obat, dan aturan pemakaiaan yang telah dianalisis. Berdasarkan data penelitian, dapat disimpulkan 72% pasien DM tipe 2 menggunakan terapi pengobatan OAD (Obat Anti Diabetik). Terapi pengobatan OAD tunggal sebesar 36% menjadi pilihan utama, OAD dari golongan Biguanide sebesar 26% adalah lini pertama dan agen farmakologi awal yang disukai. Terapi pengobatan OAD+Insulin sebesar 28%, dan pemilihan insulin long- acting sebesar 18%, sedangkan terapi pengobatan OAD kombinasi sediaan dari golongan biguanide+sulfonilurea sebesar 16%.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUAH TOMAT (Solanum lycopersicum L.) TERHADAP BAKTERI Propionibacterium acnes Elly Purwati
AFAMEDIS Vol. 2 No. 2 (2021): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (402.258 KB)

Abstract

Acne is a skin infection disease, one of which is caused by bacteria. Treatment with antibiotics can cause resistance, so it is needed alternative treatment of natural ingredients and tomatoes (Solanum lycopersicum L.) is one of the natural ingredients that contain alkaloid compounds, flavonoids, saponins and tannins that are known to have an antibacterial effect. The purpose of this study was to find out the antibacterial activity of tomato extract against the growth of Propionibacterium acnes bacteria. Tomato fruit extract is divided into 3 concentration series (20%, 40% and 60%). Testing the taste of Propionibacterium acnes using diffusion method (Kirby and Bauer diffusion) by disc diffusion. Clindamycin is used as a positive control, and Aquadest as a negative control. The results of the study showed that the concentration of inhibition zone was 20% with an average of 1.08 mm, a concentration of 40% with an average of 3.74 mm, a concentration of 60% with an average of 5.14 mm, and clindamycin (positive control) with an averageof 9.15 mm and test data Kruskall-wallis obtained a value of 0.00 less than 0.05, it can be concluded that tomato fruit extract (Solanum lycopersicum L.) can inhibit the growth of Propionibacterium acnes bacteria with a significant difference andit is known that tomato fruit extract (Solanum lycopersicum L.) concentration of 60 % the most influential in inhibiting the growth of Propionibacterium acnes bacteria. Keywords : Acne, Tomato (Solanum lycopersicum L.), Propionibacterium acnes, Antibacteria