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Zulfisa
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Agriculture, Biological Sciences & Forestry Chemistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Other

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POTENSI SEDIAAN HAND SANITIZER EKSTRAK AIR DAUN BIDARA ARAB (Ziziphus Spina-christi L.) SEBAGAI ANTIBAKTERI Trie Yuni Elfasyari; Suci Santana; Shinta Sari Dewi; Zulfisa
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.62

Abstract

Arabian sidr leaves (Ziziphus spina-christi L.) contain secondary metabolites such as alkaloids, flavonoids, saponins, tannins, and phenolics, which have the potential to act as antibacterial agents. This study was designed to evaluate the antibacterial activity of a hand sanitizer formulation containing aqueous extract of Ziziphus spina-christi leaves (EADBA). The stability of the hand sanitizer was assessed through organoleptic tests, homogeneity, pH, viscosity, hedonic evaluation, and antibacterial activity against Staphylococcus aureus using the phenol coefficient method. The antibacterial test was conducted by observing turbidity in a bacterial suspension after the addition of the sample at minutes 5, 10, and 15. Results indicated that the EADBA hand sanitizer remained physically stable during four weeks of storage at both cold (4±2°C) and room temperature (±25°C). Formulations F1 and F2 demonstrated antibacterial activity equivalent to that of phenol, as evidenced by a phenol coefficient value of one.
Edukasi Pemanfaatan Tanaman Bidara (Ziziphus mauritiana L) sebagai Obat Tradisional di Pondok Pesantren Madinatul Munawarah Bukittinggi Elfasyari, Trie Yuni Elfasyari; Zulfisa; Mevy Trisna
Jurnal Bakti Nusantara Vol. 3 No. 1 (2025): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jutira.v3i1.103

Abstract

Seiring berkembangnya sain dan teknologi, masyarakat Indonesia semakin memilih pengobatan tradisional berbasis tumbuhan karena lebih murah, aman, dan tidak memiliki efek samping yang signifikan dibandingkan pengobatan kimia sintetis. Tanaman bidara (Ziziphus mauritiana L.), yang kaya akan senyawa bioaktif seperti flavonoid dan saponin, telah terbukti memiliki berbagai manfaat kesehatan, termasuk sebagai antioksidan, antiinflamasi, dan agen penenang alami. Di Pondok Pesantren Madinatul Munawarah Bukittinggi, program pengabdian masyarakat ini dilakukan untuk meningkatkan pengetahuan dan kemampuan santri tentang penggunaan tanaman bidara sebagai obat tradisional. Pengolahan daun bidara menjadi teh, salep, dan ramuan penghilang nyeri diajarkan dalam kegiatan ini. Hasil kuesioner menunjukkan peningkatan signifikan dalam pemahaman peserta mengenai manfaat dan pengolahan tanaman bidara dimana 90% peserta mengaku mampu mengolah tanaman bidara secara mandiri.
HPLC-DAD PROFILING OF SIDR LEAVES AND ROASTED CANDLENUT FOR ALOPECIA THERAPY Elfasyari, Trie Yuni; Zulfisa; Mevy Trisna
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3455

Abstract

Alopecia is a dermatological disorder characterised by progressive hair loss, often impairing patients’ quality of life. Conventional therapies, such as minoxidil and finasteride, have demonstrated efficacy; however, their adverse effects have prompted the search for natural-based alternatives. Sidr leaves (Ziziphus spina-christi L.) and roasted candlenut seeds (Aleurites moluccanus L.) have been traditionally employed in ethnopharmacology for hair treatment, yet scientific data on their phytochemical composition remain limited. This study aimed to identify and quantify the major bioactive constituents in purified aqueous extracts of sidr leaves and roasted candlenut seeds using high-performance liquid chromatography coupled with diode-array detection (HPLC-DAD), and to assess their potential implications in alopecia therapy. Powdered sidr leaves and roasted candlenut seeds were extracted, fractionated, and analysed on a C18 column using a gradient acetonitrile–water mobile phase. The results revealed that sidr leaves are rich in rutin hydrate (245.64 ± 0.73 mg/L), accompanied by gallic acid (47.63 ± 0.43 mg/L) and quercetin (6.85 mg/L), whereas roasted candlenut seeds predominantly contain quercetin (27.00 mg/L). Rutin functions as an antioxidant and angiogenesis stimulator, gallic acid exhibits anti-inflammatory activity, and quercetin acts as a 5α-reductase inhibitor relevant to androgenetic alopecia. In conclusion, the phytochemical profiles of sidr leaves and roasted candlenut seeds support their potential use as phytotherapeutic candidates for alopecia management.
Co-Authors Elfasyari, Trie Yuni Mevy Trisna Shinta Sari Dewi Suci Santana