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KEBO LEAF ETHANOL EXTRACT (Euphorbia hirta L.) ANTI-INFLAMMATORY EFFECTS IN FEMALE WHITE RATS DETERMINED USING ARTIFICIAL UDEMA METHOD Mevy Trisna; Renatalia Fika; Budi Setiawan; Rini Wulandari
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (898.552 KB) | DOI: 10.55606/klinik.v1i2.683

Abstract

An ordinary protective reaction to tissue damage brought on by physical trauma, chemical agents, or harmful microbiological agents is inflammation. The kebo excerpt plant has significant amounts of flavonoids, which have anti-inflammatory and antioxidant properties. This study used the artificial udema method to determine the anti-inflammatory effects of Kebo Petikan leaves (Euphorbia hirta L.) ethanol extract in female white rats. This study applied a subcutaneous 1% carrageenine inducer as an anti-inflammatory drug on the soles of rats' feet. Following the injection of the test material at doses of 26 mg, 52 mg, and 104 mg, a decrease in volume was the metric that was observed. The results of the study showed the anti-inflammatory effect of ethanol extract of kebo petikan leaves at a dose of 26 mg/5ml had a strength of 32.3%, a dose of 52 mg/5ml had a strength of 78.48 %, and a dose of 104 mg/5ml had a strength of 91.46% compared to drugs.
Profil Peresepan Analgetik Antipiretik di UPT Puskesmas X Kabupaten Tanah Datar Renatalia Fika; Muhajri Agusfina; Mevy Trisna; Budi Setiawan; Yulia Ningsih
Journal Pharma Saintika Vol. 8 No. 1 (2024): Jurnal Pharma Saintika 
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i1.52

Abstract

This study analyzed the prescription profile of Analgesics - Antipyretics at the X Health Center UPT, Tanah Datar Regency in 2022 with retrospective data from 600 patient prescriptions. The results showed the highest use of Analgesics - Antipyretics in the adult age group (26-45 years) at 27.80% and the lowest was in the children's age group (5-11 years) at 17.50%. More women (50.83%) used Analgesics - Antipyretics than men (49.17%). Paracetamol tab 500mg was the most frequently prescribed type (66.67%), followed by Paracetamol syrup (16.83%) and Ibuprofen 400 mg (16.50%). This information is important for the X Health Center UPT to improve health services and more effective drug management. However, further research is needed to better understand the pattern of Analgesics - Antipyretics use in the area.
Edukasi Pemanfaatan Tanaman Bidara (Ziziphus mauritiana L) sebagai Obat Tradisional di Pondok Pesantren Madinatul Munawarah Bukittinggi Elfasyari, Trie Yuni Elfasyari; Zulfisa; Mevy Trisna
Jurnal Bakti Nusantara Vol. 3 No. 1 (2025): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jutira.v3i1.103

Abstract

Seiring berkembangnya sain dan teknologi, masyarakat Indonesia semakin memilih pengobatan tradisional berbasis tumbuhan karena lebih murah, aman, dan tidak memiliki efek samping yang signifikan dibandingkan pengobatan kimia sintetis. Tanaman bidara (Ziziphus mauritiana L.), yang kaya akan senyawa bioaktif seperti flavonoid dan saponin, telah terbukti memiliki berbagai manfaat kesehatan, termasuk sebagai antioksidan, antiinflamasi, dan agen penenang alami. Di Pondok Pesantren Madinatul Munawarah Bukittinggi, program pengabdian masyarakat ini dilakukan untuk meningkatkan pengetahuan dan kemampuan santri tentang penggunaan tanaman bidara sebagai obat tradisional. Pengolahan daun bidara menjadi teh, salep, dan ramuan penghilang nyeri diajarkan dalam kegiatan ini. Hasil kuesioner menunjukkan peningkatan signifikan dalam pemahaman peserta mengenai manfaat dan pengolahan tanaman bidara dimana 90% peserta mengaku mampu mengolah tanaman bidara secara mandiri.
TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN OBAT ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI RS X PEKANBARU Muhajri Agusfina; Renatalia fika; Ainun Naim; Mevy Trisna; Ahmad Asrawi
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.72

Abstract

Abstract: Pharmacy personnel play a role in providing accurate, clear and up-to-date information to patients. Providing drug information to patients is important so that patients receive the right and proper treatment. This study aims to determine the level of patient satisfaction with drug services for outpatients at X Hospital. This study is an observational/survey study with a descriptive research design. Based on the results of the study conducted on the level of public satisfaction with drug services by pharmacy personnel at X Hospital, Pekanbaru, the level of satisfaction was obtained in the Satisfied category (67%). This result is an average of 5 dimensions of satisfaction, namely reliability 59% in the quite satisfied category, responsiveness 70% in the satisfied category, attention (empathy) 68% in the very satisfied category, assurance 69% in the satisfied category, tangible facilities 69% in the satisfied category. The level of patient satisfaction with drug services at X Hospital from the five dimensions of satisfaction does not have a very satisfied category.
BIOAKTIFITAS ANTIINFLAMASI EKTRAK METANOL RIMPANG SIJANGKANG (Hornstedtia scyphifera var. Fusiformis Holttum) TERHADAP TIKUS PUTIH JANTAN Mevy Trisna; Renatalia Fika; Ilza Fitri Handayani; Ainun Naim; Muhajri Agusfina
Journal Pharma Saintika Vol. 8 No. 2 (2025): Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v8i2.78

Abstract

An investigation examined the anti-inflammatory effects of the methanol extract from the Sijangkang rhizome (Hornstedtia scyphifera var. Fusiformis Holttum) on male albino rats that were induced with 1% carrageenan at a volume of 0.2 ml/rat. The tool used in this test is a Plethysmometer with a working principle using Archimedes' law. A Plethysmometer is a tool used to measure edema volume. The way it works is based on measuring the volume of fluid due to the immersion of the organ whose degree of inflammation is measured into mercury liquid. The working principle is that if an object is dipped into a liquid, the object will get an upward pressure equal to the liquid that is pushed by the object. From the results of the research that has been done, it can be concluded that the methanol extract of sijangkang rhizome has anti-inflammatory activity. The research conducted is an experimental study using 12 test animals consisting of 4 treatment groups, namely 1 negative control group (aquadest), and 3 groups of test substances methanol extract of sijangkang rhizome. The doses used were 2 mg/200 g BW/5 ml, 4 mg/200 g BW/5 ml, and 8 mg/g BW/5 ml. The negative control group and the test group with doses of 4 mg/200 g BW and 2 mg/200 g BW showed a very high and continuously increasing percentage of edema formation. This was due to the fact that the negative control group received only distilled water, while the test group was administered a small amount of the test substance that failed to prevent edema formation. In contrast, the test substance, at a dose of 8 mg/200 g body weight/5 ml, exhibited anti-inflammatory properties.