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All Journal Public Health of Indonesia Jurnal Kefarmasian AKFARINDO DUNIA KEPERAWATAN: JURNAL KEPERAWATAN DAN KESEHATAN Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Jurnal Stunting Pesisir dan Aplikasinya
Dali
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Dentistry Education Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Pengaruh Pola Menyusui Terjadwal Terhadap Peningkatan BB Bayi Sebagai Upaya Pencegahan Stunting Sulupadang, Prishilla; Samsuddin; Dali
Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan Vol 12 No 1 (2024): Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan
Publisher : School of Nursing, Faculty of Medicine and Health Science, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jdk.v12i1.549

Abstract

Bayi yang tidak mendapat cukup ASI pada awal kehidupan sangat berisiko mengalami masalah kekurangan zat gizi seperti stunting yang dapat mempengaruhi produktivitas dan gangguan pada pertumbuhan dimasa yang akan datang. Salah satu tanda objektif dari kecukupan ASI yaitu peningkatan BB yang adekuat. Tujuan Penelitian untuk mengetahui pengaruh pola menyusui terjadwal terhadap peningkatan BB bayi sebagai upaya pencegahan stunting di wilayah kerja puskesmas motui dan sawa Kabupaten Konawe utara. Pengambilan sampel menggunakan total sampling dengan mengambil seluruh ibu menyusui yang memiliki bayi usia 0-6 bulan dan belum mendapat MP-ASI berjumlah. 40 responden (20 intervensi dan 20 kontrol). Metode yang digunakan adalah quasi eksperimen dengan pendekatan pre post test with control group. Hasil penelitian secara statistik terdapat perbedaan BB yang bermakna antara sebelum dan setelah menyusui sesuai jadwal (nilai p < 0,05). Penerapan pola menyusui terjadwal dapat diterapkan kepada Ibu yang memiliki bayi 0-6 bulan untuk mengoptimalkan peningkatan BB bayi  
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN JARAK MERAH (Jatropha gossypiifolia) ASAL KABUPATEN BANTAENG Wahyuddin, Nurzadrina; Ismail, Ismail; Mashar, Harlyanti Muthma'innah; Dali
Jurnal Kefarmasian Akfarindo Vol 7 No 1 (2022)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.vi0.115

Abstract

Background: In the last few decades there has been an increase in cases of chronic diseases and premature aging which are some of the key factors in influencing public health. This condition is caused by various causes, but the main factor is the number of free radicals that exceed the body's capacity to neutralize them. Antioxidants have an important role as health protective factors because they can neutralize and protect cells from the presence of free radicals. Red castor leaves have been reported to have good activity as an antioxidant. The chemical content of this plant is anthraquinone, flavonoid, saponin, tannin and terpenoid. Objective: This study aimed to evaluate the antioxidant activity of red jatropha leaf extract using the DPPH method. Methods Samples were extracted using 70% ethanol by maceration method. The antioxidant activity test was carried out using the DPPH method (1,1-diphenyl-2-picrylhydrazyl) using a comparison of Vitamin C. Each test used a variation of the concentration of the solution. For red jatropha leaf extract using concentration variations of 20, 40, 60, 80 and 100 g/ml, while for vitamin C using concentration variations of 10, 15, 20, 25, and 30 g/ml. The absorbance of each test solution was measured using a spectrophotometer at a wavelength of 515 nm. The results are reported as IC50 values. Results: The results showed that the IC50 values ​​of red jatropha leaf extract and vitamin C were 47.81 and 14.99 g/ml, respectively. This value indicates that the Chinese jatropha leaf extract has a very strong antioxidant activity (IC50 <50 g/ml). Conclusion: Red jatropha leaf extract showed very strong antioxidant activity with an IC50 value of 47.81 g/ml so it has great potential as an antioxidant that can be used for the development of traditional medicinal raw materials.
ANALISIS KADAR FLAVONOID TOTAL FRAKSI ETIL ASETAT KULIT BATANG SIRSAK (Annona muricata L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Mashar, Harlyanti Muthma'innah; Itma Annah; Dali; Teguh Supriyono
Jurnal Kefarmasian Akfarindo Vol 8 No 1 (2023)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.v8i1.161

Abstract

Pendahuluan: Sirsak merupakan tanaman yang memiliki buah dengan kandungan nutrisi dan senyawa kimia yang telah banyak digunakan untuk pengobatan tradisional, dan kaya akan senyawa antioksidan. Aktivitas antioksidan ini dapat menghambat stres oksidatif. Aktivitas antioksidan tersebut terkait dengan kandungan senyawa kimia yang tinggi pada berbagai bagian tubuh tumbuhan ini. Klika sirsak mengandung berbagai senyawa, salah satunya adalah flavonoid. Flavonoid memiliki efek biokimia dan antioksidan yang banyak dimanfaatkan untuk meningkatkan kesehatan. Berbagai penelitian melaporkan bahwa flavonoid memiliki potensi sebagai anti inflamasi, anti alergi, antivirus, antikarsinogenik, serta terapeutik dan sitotoksik. Tujuan: Penelitian ini bertujuan untuk menganalisis kadar flavonoid total ekstrak etil asetat klika sirsak dengan metode spektrofotometri UV-VIS. Metode: Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol, dan dilanjutkan dengan proses partisi dengan pelarut etil asetat sehingga diperoleh ekstrak etil asetat. Analisis kadar flavonoid total dilakukan dengan metode spektrofotometri UV-Vis menggunakan larutan baku rutin pada konsentrasi 10, 20, 30, dan 40 ppm. Absorbansi larutan baku rutin dan ekstrak diukur pada Panjang gelombang 415 nm. Hasil: Hasil ekstraksi dengan pelarut etanol dan dilanjutkan dengan proses partisi dengan pelarut etil asetat diperoleh ekstrak etil asetat sebanyak 1,6 g dan nilai rendemen sebesar 10,67%. Hasil analisis kadar flavonoid total sampel dan didapatkan hasil yaitu kadar flavonoid total dari ekstrak etil asetat klika sirsak adalah 118,266 mg ER/g dengan persentase 11,8266 %. Kesimpulan: Ekstrak etil asetat klika sirsak positif mengandung flavonoid dan sebanyak 1 mg/mL sampel mengandung flavonoid total sebesar 118,266 mg ER/g dengan persentase 11,8266 %.
Nutritional Education And Use Of Local Food For Mothers Of Toddlers In Preventing Stunting At 1000 HPK Rosnah, Rosnah; Sarita, Sultina; Dali; Rofiqoh; La Banudi; Toruntju, Sultan Akbar
Jurnal Stunting Pesisir dan Aplikasinya Vol 2 No 1 (2023): Januari-Juni
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/jspa.v2i1.1566

Abstract

Stunting is chronic malnutrition in toddlers resulting from a lack of nutritional intake for a long time and is usually accompanied by frequent illnesses. The target audience for this community service activity is 30 mothers of toddlers. The method used is health education in the form of counseling and interactive discussions. This activity was carried out on June 2 2022 at the Puuwonua Village Hall, working area of ??the Lalonggasu Meeto Community Health Center, Konawe Regency. The results of this community service activity showed that there was an increase in knowledge about nutrition after providing counseling to mothers of toddlers who had an average pre-test score of 6.0 which rose to 8.6 at post-test; The results of the analysis of different tests showed that there was a difference in the mean knowledge scores of participants before and after counseling (p=0.000). Conclusion: implementing outreach to increase nutritional knowledge among mothers of toddlers has proven to be effective, especially in implementing balanced nutrition within 1000 HPK and using local food in efforts to prevent stunting.
EDUKASI MASYARAKAT TENTANG PERTOLONGAN PERTAMA RESUSITASI JANTUNG PARU PADA KASUS TENGGELAM DI KELURAHAN SAWA, KAB. KONAWE UTARA Amandaty, Srikandi Puspa; Nurjannah; Wijayati, Fitri; Dali; Nurdin
Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Vol 5 No 1 (2025): Januari-Juni
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/jippm.v5i1.1670

Abstract

Indonesia is an archipelagic country with many oceans, rivers and lakes. The number of drowning incidents is still unknown because many cases are not reported and many victims do not receive medical services. Based on data from the National Search and Rescue Agency (BASARNAS) of Southeast Sulawesi in 2015 from various locations, 12 people died from drowning, this number is relatively small compared to 2016, the number of drowning victims increased by 17 people and in the last year of 2017 until the end of February, 2 drowning victims were reported. The latest BASARNAS data in 2023 showed 43 cases of ship accidents and 24 cases of dangerous conditions for humans. Providing first aid education requires real action for the general public so that they can provide assistance to drowning victims. The implementation of this community service began with a pre-test followed by counseling on drowning and practicing how to perform CPR in drowning cases, ending with a post-test by the Sawa Village community of 40 people. The pre-test results showed that the level of public knowledge before being given counseling was mostly sufficient with a total of 22 people (55%), less knowledge 17 people (42%) and good knowledge 1 person (3%). After being given counseling, there was an increase in sufficient knowledge of 23 people (57%), good knowledge of 15 people (38%) and less knowledge decreased to 2 people (5%). Health Counseling on First Aid for Cardiopulmonary Resuscitation in Drowning Cases has succeeded in increasing public knowledge in Sawa Village, North Konawe Regency.
SCREENING AND HEALTH EDUCATION ON HEALTH ISSUES RELATED TO DIVING AMONG TRADITIONAL FISHERMEN IN LEPPE VILLAGE, SOROPIA DISTRICT, KONAWE REGENCY Nurfantri, Nurfantri; Dali; Saranani, Muhaimin; Risfandi
Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Vol 5 No 2 (2025): Juli-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/jippm.v5i2.1706

Abstract

Nelayan penyelam tradisional dapat mengalami barotrauma dan Dekompresi yang menunujukkan kondisi kegawatdaruratan penyelaman. Mengetahui gambaran pengetahuan masyarakat tentang penyakit dekompresi cara pencegahan dan mengidentifikasi keluhan Dekompresi dan Barotrauma melalui skrining kesehatan di Desa Leppe Kec. Soropia Kabupaten Konawe. Metode : Pemberian edukasi dilakukan dalam bentuk penyuluhan dan skrining kesehatan, Sasaran kegiatan ini adalah penyelam tradisional di desa Leppe Kec.Soropia Kab. Konawe, berjumlah 30 orang. Hasil. Tingkat pengetahuan responden sebelum pemberian edukasi, nampak persentase responden berpengetahuan kurang 15 responden atau 50%) dan cukup sebanyak 7 responden atau 23,3 % mengalami penurunan dengan jumlah responden berpengetahuan rendah menjadi 5 responden (16%) dan berpengetahuan cukup meningkat menjadi 12 responden (40%), sehingga persentase responden berpengetahuan baik yang sebelumnya sebesar 8 responden ( 26,6%) mengalami peningkatan menjadi 13 responden (43%). Beberapa gejala dirasakan oleh > 50 % nelayan, diantaranya gangguan kulit berupa rasa gatal dan Nampak rash ( kebiruan ) pada kulit, masalah musculoskeletal seperti nyeri sendi dan otot), Ditemukan nelayan yang pernah mengalami kelumpuhan hingga kesulitan mengeluarkan urine Perlunya dilakukan edukasi terkait penyalaman yang sehat (sesuai standar). Bekerjasama dengan instansi lintas sector terkait pelatihan metode penangkapan selain metode penyelaman. Kata Kunci : Nelayan, Dekompresi, Penyuluhan, skrining
The Cytotoxicity of Endophytic Fungi Isolated from Kelakai (Stenochlaena palustris) Against MCF-7 and Vero Cells Dali; Mashar, Harlyanti Muthma’innah; Damiti, Sukmawati Ahmad; Ysrafil, Ysrafil
Public Health of Indonesia Vol. 11 No. 3 (2025): July - September
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i3.1002

Abstract

Background: The high prevalence of cancer has a direct impact on the quality of life and nutritional status of sufferers, mainly due to decreased appetite, metabolic disorders, and side effects of conventional therapies such as surgery, mastectomy, chemotherapy, hormonal therapy, or radiation therapy. These therapies, although aimed at inhibiting the growth and metastasis of cancer cells, often cause severe side effects that worsen the patient's condition. Therefore, it is important to explore alternative treatments that are effective and have minimal side effects. In this regard, biological sources, such as endophytic fungi kelakai, contain various active secondary metabolites that can inhibit cancer cell proliferation so that they can be part of a more public health-friendly supportive therapy approach.Objective: This study aims to prove the cytotoxic activity of the extract of endophytic fungi in kelakai against MCF-7 and Vero cells.Methods: Isolation, purification, and extraction process of secondary metabolites from the endophytic fungi isolates were carried out in the same manner as our previous research. The ethyl acetate extract of kelakai was obtained by extractive fermentation from pure isolates of the endophytic fungi in kelakai. Extraction was carried out by the fractionation method using the ethyl acetate solvent at a ratio of 1:1. Identification of chemical contents, including tannins, alkaloids, flavonoids, saponins, and steroids/terpenoids, was conducted qualitatively. Cytotoxic activity was tested by the MTT method.Results: From the isolate extraction, 2.4 g of ethyl acetate extract was produced. The identification of chemical contents showed positive results, meaning that the extract did contain tannins, flavonoids, alkaloids, steroids, and saponins. The extract cytotoxicity test against MCF-7 and Vero cells yielded IC50 values of 517.3015 μg/ml and 1,074.9152 μg/ml, respectively. Conclusion: Based on these results, the extract of kelakai was not toxic to Vero cells, but it was toxic to MCF-7 cells. These findings suggest that the kelakai can be the basis for exploring local plants as a source of natural medicine while supporting the conservation of endemic plants to provide safer alternative therapies and improve public health. Keywords: Stenochlaena palustris; Endophytic Fungi; MTT; MCF-7; Vero cell
Co-Authors Annah, Itma Damiti, Sukmawati Ahmad Harlyanti Muthma'innah Mashar Ismail Ismail La Banudi Mashar, Harlyanti Muthma’innah Nurdin Nurfantri, Nurfantri Nurjannah Risfandi Rofiqoh Rosnah, Rosnah Samsuddin Saranani, Muhaimin Sarita, Sultina Srikandi Puspa Amandaty Sulupadang, Prishilla Teguh Supriyono Toruntju, Sultan Akbar Wahyuddin, Nurzadrina Wijayati, Fitri Ysrafil, Ysrafil