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All Journal Medicina IPTEKMA journal of internal medicine Buletin Udayana Mengabdi E-Jurnal Medika Udayana Health Science Journal of Indonesia The Indonesian Biomedical Journal Universa Medicina Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Penyakit Dalam Udayana ISM (Intisari Sains Medis) : Jurnal Kedokteran Indonesian Journal of Cancer Jurnal Penyakit Dalam Indonesia

I Gusti Putu Suka Aryana

Divisi Geriatri, Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Udayana, Bali

Author-ID : 234375

Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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KORELASI ANTARA GERIATRIC NUTRITIONAL RISK INDEX DENGAN LAMA RAWAT PASIEN GERIATRI DI RUMAH SAKIT SANGLAH, DENPASAR Andriyasa, K; Kuswardhani, RA Tuty; Aryana, IGP Suka; Astika, N; Putrawan, IB
journal of internal medicine Vol. 12, No. 2 Mei 2011
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (90.941 KB)

Patients at risk of malnutrition are associated with a poor outcome. There are several tools that we can use to assess thenutritional status. European Society of Parenteral and Enteral Nutrition (ESPEN) guidelines and the French Program NationalNutrition Sante (PNNS) recommend Mini Nutritional Assessment (MNA) to detect the risk of under nutrition among elderlysubjects. The MNA which based on a Questionnaire does not use biological indicators. It is more adapted to the elderly at homeor nursing home setting than hospitalization. We want to evaluate the new tool Geriatric Nutritional Risk Index (GNRI) that moresimple than MNA to assess nutritional status and predict hospitalization outcomes in geriatric patients.This is a cohort study to evaluated correlation between GNRI score with length of stay in elderly patients. We evaluatednutritional status using Geriatric Nutritional Risk Index (GNRI) and Mini Nutritional Assessment (MNA) for elderly patientsthat admitted in Sanglah Hospital (Internal Department, class III) between February 2010 and April 2010. The patients werenutritionally assessed within 48 hours of hospital admission and studied in correlation to length of stay and in-hospital mortality.Fifty complete assessments were available for analysis. There are 32 male (62%) and 18 female (38%) with mean age are67.2 (60 ? 82) years old. GNRI score and MNA correlated inversely with length of stay in elderly patients (r = -0.67; p < 0.000)and (r = -0.44; p = 0.004) respectively. There are three fatal outcome (death) and all of cases with GNRI score grade 4 (majorrisk, GNRI score < 82) . GNRI score has a significant correlation with MNA score (r = 0.72; p < 0.000).In conclusion: Poor nutritional status as measured by GNRI was associated with a longer length of stay and increased inhospitalmortality. GNRI is a simple tool and has more significant correlation with hospitalization outcomes than MNA.

KORELASI ANTARA OBESITAS SENTRAL DENGAN ADIPONEKTIN PADA LANSIA DENGAN PENYAKIT JANTUNG KORONER Aryana, IGPS; Kuswardhani, RA Tuty; Suastika, K; Santoso, A
journal of internal medicine Vol. 12, No. 2 Mei 2011
Publisher : journal of internal medicine

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Obesity is rapidly becoming a global problem not only in developed countries but also in developing countries such asIndonesia. Visceral obesity (central obesity) is an importance risk for cardiovascular disease and recognition that adipose tissuecan be regarded as a large endocrine organ that secreted inflammatory and anti inflammatory molecules (adiponectin). This studyaims to know the correlation between central obesity and adiponectin in geriatric Coronary Heart Disease (CHD) patients.Thisstudy was cross sectional analytic study of geriatric CHD at out and in patients in Sanglah Hospital. Data are presented as groupmean ± SD and analyzed by t-test, chi-square, and Pearson correlation with SPSS 12 software.Forty five patients (35 males and 10 females), 23 patient unstable angina pectoris, 14 patient acute myocardial infarction,and 8 patient stable angina pectoris were recruited and examined. There was high prevalence of central obesity 51.1% (23patients). Mean of log adiponectin were significantly difference between central obese and non central obese (1.80 ± 0.61 vs 1.09± 0.41 with p). Central obesity increased risk of hypoadiponectinemia 5 times than non central obesity (p = 0.011, CI 95% 1.4- 17.8). Waist circumference has negative correlation with log plasma adiponectin (R = -0.663, p < 0.001).There was high prevalence of central obesity in geriatric coronary heart disease patients. Central obesity increased risk ofhypoadiponectinemia 5 times than non central obesity. Waist circumference has negative correlation with plasma adiponectin.Increased of waist circumference will decrease of adiponectin (cardioprotective protein) and will increase risk of Acute CoronarySyndrome in geriatric patients.

PELAYANAN KESEHATAN LANJUT USIA DI WILAYAH KERJA PUSKESMAS I DENPASAR SELATAN I.G P.S. Aryana; R. A.T. Kuswardhani; I. N. Astika; I. B.P. Putrawan; N. K.R. Purnami; A. A.M.P. Triningrat; I.D. G.A.E. Putra; N. K.S. Diniari; K. Widyastuti
Buletin Udayana Mengabdi Vol 21 No 1 (2022): Buletin Udayana Mengabdi
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

The number of elderly reached 6146 elderly (23.44% of the total population) in South Denpasar sub-district. The complexity of the health problems experienced by the elderly and the special character possessed by the elderly, it is necessary to use a different method and approach by conducting a comprehensive health examination (bio-psycho-social aspect) which aims to provide an understanding for the elderly to their own health and improve their abilities and abilities. the role of family and community in overcoming the health of the elderly. The activities carried out include health services for the elderly with a comprehensive health examination including a plenary assessment of geriatric patients (P3G), physical examination, eyes, ENT, mental and nervous health). Community service is carried out for the elderly in Sesetan Village, South Denpasar. There are 130 seniors who participated in this service. The elderly with the age group 60 - 69 years amounted to 72 people (55.4%) who attended the most health services. 44 men (33.8%) and 86 people (66.2%) were female. The results of the examination showed that 75 people (57.7%) were suffering from infectious diseases, 8 people (6.2%) were malnourished, 49 people (37.7%) were obese, and 25 people (19.2%) had sarcopenia. (loss of muscle mass). Based on the results of the elderly health examination, this elderly health service activity is expected to provide benefits to the elderly and their families. Keywords: Elderly, medical examination, comprehensive, family role, quality of lif

HUBUNGAN ANTARA SIKAP SLEEP HYGIENE DENGAN DERAJAT INSOMNIA PADA LANSIA DI POLIKLINIK GERIATRI RSUP SANGLAH, DENPASAR Ni Made Putri Suastari; Pande Nyoman Bayu Tirtayasa; I Gusti Putu Suka Aryana; RA Tuty Kusumawardhani
E-Jurnal Medika Udayana vol 3 no 9 (2014):e-jurnal medika udayana
Publisher : Universitas Udayana

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Insomnia merupakan gangguan tidur yang paling sering dialami oleh lansia. Insomnia berpengaruh langsung terhadap penurunan kualitas hidup dan memiliki kecenderungan terhadap peningkatan angka morbiditas dan mortalitas pada lansia. Selama ini berbagai terapi pengobatan telah dikembangkan untuk membantu mengatasi keluhan, namun belum ditemukan suatu terapi pengobatan yang ideal bagi lansia penderita insomnia. Melihat fenomena di atas, maka diperlukan metode dalam penatalaksanaan insomnia pada lansia melalui pendekatan terapi nonfarmakologis dan hanya menggunakan obat-obatan pada saat yang mendesak. Terapi nonfarmakologis yang paling efektif adalah terapi perilaku, yaitu sleep hygiene. Sleep hygiene merupakan identifikasi dan modifikasi perilaku dan lingkungan yang mempengaruhi tidur. Sehubungan hal diatas, penulis tertarik untuk mengetahui hubungan antara sikap sleep hygiene dengan derajat insomnia pada lansia di Poliklinik Geriatri RSUP Sanglah. Penelitian ini merupakan studi analitik cross-sectional dengan sampel sebanyak 43 lansia yang berkunjung ke Poliklinik Geriatri RSUP Sanglah pada bulan Februari 2014. Data diperoleh dengan wawancara melalui kuisioner yang terstruktur meliputi identitas, sikap sleep hygiene, dan derajat insomnia menggunakan kuesioner Insomnia Severity Index. Penelitian ini memperoleh rerata jenis kelamin, pendidikan, dan pekerjaan pada masing-masing derajat insomnia adalah homogen. Berdasarkan uji korelasi diperoleh bahwa terdapat hubungan antara sikap sleep hygiene dengan derajat insomnia pada lansia di Poliklinik Geriatri RSUP Sanglah pada dua komponen, yaitu faktor diet (p=0,006) dan olahraga (p=0,010), sedangkan tidak terdapat hubungan antara sikap sleep hygiene dengan derajat insomnia pada lansia di Poliklinik Geriatri RSUP Sanglah pada dua komponen lainnya, yaitu faktor perilaku (p=0,374) dan lingkungan (p=0,222).

The The relationship between IL-6 and CRP with Sarcopenia in indigenous elderly population at Pedawa Village, Buleleng, Bali, Indonesia Suka Aryana; AA Wiradewi Lestari; I.B. Putrawan; Ni Ketut Rai Purnami; I Nyoman Astika; R.A. Tuty Kuswardhani
Health Science Journal of Indonesia Vol 9 No 1 (2018)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/hsji.v9i1.467

Abstrak Latar belakang: Sarkopenia adalah sindrom yang ditandai dengan penurunan massa otot disertai penurunan kekuatan otot dan atau fungsi otot. Stres oksidatif dan proses inflamasi dikenal sebagai faktor pemicu untuk sarkopenia dengan melepaskan rangsangan katabolik interleukin-6 (IL-6) dan protein C-reaktif (CRP). Penelitian ini bertujuan untuk menentukan hubungan antara IL-6 dan kadar CRP terhadap parameter sarkopenia seperti massa otot, kekuatan pegangan, dan kecepatan berjalan. Metode: Penelitian ini menggunakan desain cross-sectional analitik yang dilakukan di Desa Pedawa, Kabupaten Buleleng, Bali pada bulan Agustus 2016. Sekitar 79 responden berusia ≥ 60 tahun menggunakan teknik sampling acak stratifikasi. Variabel yang dinilai yaitu parameter sarkopenia (massa otot, kekuatan pegangan, dan kecepatan berjalan) termasuk IMT, serta IL-6 dan pemeriksaan tingkat CRP. Uji korelasi spearman dan parsial digunakan untuk menilai korelasi antara parameter IL-6, CRP, dan sarkopenia. Hasil: Kadar IL-6 dan CRP tidak berkorelasi signifikan dengan tiga parameter sarkopenia. Kadar CRP berkorelasi dengan IL-6 (r = 0.37; p = 0.001) dan IMT (r = 0.29; p = 0.009). Pada kelompok pria, IL-6 hanya berkorelasi dengan CRP (r = 0.40; p = 0.011). Sedangkan pada kelompok wanita, IL-6 berkolerasi dengan CRP (r = 0.38; p = 0.017), kecepatan berjalan (r = 0.33; p = 0.037) serta CRP berkorelasi dengan IMT (r = 0.32; p = 0.049) dan massa otot total (r = -0.32; p = 0.043). Setelah penyesuaian untuk variabel IMT, IL-6 berkorelasi dengan CRP (r = 0.43; p = 0,001) dan massa otot total (r = -0.25; p = 0.026) serta secara signifikan berkorelasi pada kelompok kurus (IMT<18.5 kg/m2) (r = -0.50; p = 0.026). CRP tidak berkorelasi secara signifikan dengan tiga parameter sarkopenia pada uji spearman, korelasi parsial, dan uji korelasi spesifik spearman berdasarkan pada kelompok IMT. Kesimpulan: Kadar IL-6 berhubungan dengan penurunan massa otot total pada keseluruhan lansia desa Pedawa setelah penyesuaian variabel IMT. Kata kunci: IL-6, Protein C-Reaktif (CRP), Sarkopenia, Lanjut usia, Desa Pedawa. Abstract Background: Sarcopenia is a syndrome characterized by decreased muscle mass with decreased muscle strength and or muscle function. Oxidative stress and inflammatory processes are known as triggering factors for sarcopenia by releasing catabolic stimuli of interleukin-6 (IL-6) and C-reactive protein (CRP).This study aims to determine the relationship between IL-6 and CRP levels to sarcopenia parameter such as muscle mass, grip strength, and walking speed. Methods: This study was an analytic cross-sectional design conducted at Pedawa Village, Buleleng District, Bali in August 2016. About 79 respondents aged ≥ 60 years using stratified random sampling technique. The assessed variables were sarcopenia parameter (muscle mass, grip strength, and walking speed) including BMI, as well as IL-6 and CRP levels examination. Spearman and partial correlation test were used to assess the correlation among IL-6, CRP, and sarcopenia parameters. Results: IL-6 levels and CRP were not significantly correlated with the three parameters of sarcopenia. CRP levels correlated with IL-6 (r = 0.37; p = 0.001) and BMI (r = 0.29; p = 0.009). In the male group, IL-6 was only correlated with CRP (r = 0.40; p = 0.011). While in the women group, IL-6 correlated with CRP (r = 0.38; p = 0.017), walking speed (r = 0.33; p = 0.037) and CRP correlated with BMI (r = 0.32; p = 0.049) and total muscle mass (r = -0.32; p = 0.043). After adjustment to BMI variable, IL-6 was correlated with CRP (r = 0,43; p = 0,001) and total muscle mass (r = -0.25; p = 0.026) and significantly correlated in underweight groups (BMI<18.5 kg/m2) (r=-0.50; p=0.026). CRP was not significantly correlated with the three parameters of sarcopenia on Spearman, partial correlation, and Spearman's specific correlation test based on BMI group. Conclusion: IL-6 levels were associated with total muscle mass loss after BMI adjustmentin Pedawa village’s elderly as a whole. Keywords: IL-6, C-Reactive Protein (CRP), Sarcopenia, Elderly, Pedawa village.

High Myostatin Serum Related with High Prevalence of Sarcopenia Among Elderly Population in Pedawa Village, Bali, Indonesia I Gusti Putu Suka Aryana; I Nyoman Astika; Raden Ayu Tuty Kuswardhani; Ida Bagus Putu Putrawan; Ni Ketut Rai Purnami; Wayan Giri Putra; Anak Agung Wiradewi Lestari; I Nyoman Wande
The Indonesian Biomedical Journal Vol 11, No 3 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i3.822

BACKGROUND: Sarcopenia is defined as a decrease in muscle mass accompanied by a decrease in muscle strength and performance. Sarcopenia arises from the disruption of the complex balance between anabolic and catabolic factors. Myostatin strongly influences muscle growth inhibition. Deletion and function loss of myostatin causes hyperplasia and skeletal muscle hypertrophy.METHODS: This study was an analytical cross-sectional study. Seventy respondents aged ≥60 years in Pedawa Village, Bali, Indonesia were selected by using the stratified random sampling technique. Sarcopenia status was assessed according to Asian Working Group for Sarcopenia (AWGS) criteria, including muscle mass, grip strength, and walking speed. While the myostatin serum levels was measured by enzyme-linked immunosorbent assay (ELISA).RESULTS: The incidence of sarcopenia in the elderly was 45 people (64.3%). Based on the analysis, there was a significant difference between myostatin levels in sarcopenia subjects (47.59 ng/mL) and non-sarcopenia subjects (39.7 ng/mL). Based on the statistical calculations, it was determined that the cut-off range of myostatin levels was 48.91 ng/mL. The prevalence ratio of sarcopenia incidence based on the myostatin levels in the elderly was 3.84, while based on the combination of age risk and myostatin levels was 9.75.CONCLUSION: Based of the data, there are significant differences of myostatin level between elderly people with and without sarcopenia. The prevalence of high myostatin levels in elderly is almost 4 times higher than low myostatin levels in the elderly.KEYWORDS: myostatin, sarcopenia, elderly

Myokine Regulation as Marker of Sarcopenia in Elderly I Gusti Putu Suka Aryana; Anak Agung Ayu Ratih Hapsari; Raden Ayu Tuty Kuswardhani
Molecular and Cellular Biomedical Sciences Vol 2, No 2 (2018)
Publisher : Cell and BioPharmaceutical Institute

The elderly population will increase as well as increasing life expectancy. Health problems in elderly will be more complex and need a comprehensive management. One of the problems that arise from the aging process is sarcopenia. Sarcopenia is a decreasing in muscle mass and muscle strength or muscle function caused by multifactorial not only due to aging process, but also nutrition, immobilization, genetics and others risk factors. Muscle is an endogen organ that produces various proteins that can affect the health system. This protein is referred to as myokine. Myokine is anti-inflammation cytokine and peptide produced by striated muscles. Physical activity results in myokine secretion that can reduce inflammation due to a sedentary lifestyle. Inflammation can lead to worsening sarcopenia and fat accumulation in striated muscles, thus reducing muscle mass, muscle strength and causing physical inactivity. The most of this type myokine have antiinflammation effect have work as autocrine, paracrine and endocrine. Chronic inflammation is a contributor that plays a role in the pathophysiology of various diseases including sarcopenia, it will protected by myokine. Myokine can affect the metabolism of glucose, fatty acids, angiogenesis, myogenesis, neurogenesis, and can explain the relationship between muscle, liver, fat, tissue and brain. Some knewn myokines include interleukin (IL)-6, IL-8, IL-5, brain-derived neurotrophic factor (BDNF), fibroblast growth factor 21 (FGF-21), leukemia Inhibitory factor (LIF), irisin and secreted protein acidic and rich in cysteine (SPARC). Physical exercise can induce myokine secretion from striated muscle to circulation. Through these mechanisms, myokine is expected to improve metabolism of glucose, fat and protein muscle, liver, fat, tissue, brain and reduce the incidence some comorbidity especially sarcopenia. Finally, it's will be decreasing of disability, morbidity and mortality rate in elderly.Keywords: myokine, sarcopenia, elderly

Pola pasien anemia yang berkunjung ke Poliklinik Hematologi RSUP Sanglah dari April 2015-April 2017 Ni Made Ayu Sintya D; I Wayan Losen Adnyana; IGP Suka Aryana
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Introduction: Anemia is a clinical condition associated with many causes. Anemia is not a disease, it is a syndrome and generally described as a decreased of red blood cell mass and hemoglobin below the normal level. Based on WHO's criteria, someone can be diagnosed with anemia if their hemoglobin level falls below 130 g/L for men and below 120 g/L for women. Based on a survey made by WHO, about one from every four people in the world suffered from anemia.Aim: The study aims to evaluate the patient arrival pattern to the Hematological Policlinic in RSUP Sanglah Denpasar.Â Method: This is analytic observational research of the anemic patient who came to the Hematological Policlinic in Sanglah General Hospital from April 2015-April 2017.Result: The highest proportion of anemic patient who came to Hematologic Policlinic in Sanglah General Hospital based on age classification are the age group of 15-59 while based on sexes the percentage of the anemic male patient is 44.2%, and the anemic female is 55.8% while 2.9% of that female is currently pregnant.Conclusion: From the causative point of view, the anemic patient in Hematologic Policlinic in Sanglah General Hospital from April 2015 to April 2017 mostly diagnosed with unspecified type while 58.7% of the anemic patient come without another health issues and the other 41.3% have had underlying or accompanying diseases.Introduction: Anemia merupakan suatu kondisi klinis yang diasosiasikan dengan banyak penyebab. Anemia bukan merupakan suatu penyakit melainkan suatu syndrome dan pada umumnya didefinisikan sebagai penurunan sel darah merah dan hemoglobin di bawah nilai normal. Berdasarkan kriteria WHO, seseorang dapat didiagnosis Anemia jika hemoglobinnya berada di bawah 130 g/L untuk laki-laki dan di bawah 120 g/L untuk perempuan. Berdasarkan survey yang dibuat oleh WHO, anemia diderita oleh satu dari empat orang di dunia.Tujuan: Penelitian ini bertujuan untuk mengetahui pola kunjungan pasien ke Poliklinik Hematologi RSUP Sangah Denpasar.Metode: Penelitian ini merupakan suatu penelitian observasional pada pasien anemia yang datang ke poliklinik hematologi RSUP Sanglah dari April 2015-April 2017.Hasil: Berdasarkan penelitian ini dapat dikonklusikan bahwa proporsi tertinggi pasien anemia yang datang ke Poliklinik Hematologi RSUP Sanglah paling banyak adalah dari kelompok umur 15-19 tahun. Sementara itu, berdasarkan kelompok jenis kelamin ditemukan bahwa presentasi pasien anemia perempuan adalah 55,8% dengan 2,9% dari pasien tersebut sedang dalam keadaan hamil sementara pasien anemia laki-laki adalah 44,2%.Simpulan: Dilihat dari penyebabnya pasien anemia yang datang ke Poliklinik Hematologi RSUP Sanglah dari April 2015-April 2017 paling banyak didiagnosis dengan tipe tidak terspesifikasi dengan 58,7% pasien anemia datang tanpa disertai penyakit lain dan 41,3% datang dengan penyakit penyerta.

Prevalensi sarkopenia dan frailty di desa Pedawe, Mangupura, Serai dan Songan I Gusti Agung Wilaja Putra; I Gusti Putu Suka Aryana; I Nyoman Astika; RA Tuty Kuswardhani; Ida Bagus Putrawan; Ketut Rai Purnami
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Frailty is characterized by a decrease in multi-organ physiological functions. Sarcopenia and frailty have a significant impact on individuals and society so it is necessary to know the prevalence in the community. This study aimed to determine the prevalence of sarcopenia and frailty in rural areasMethod: The was a cross-sectional study in the elderly population in the villages of Pedawa, Mangupura, Serai and Songan. Measurement of muscle mass using bioelectrical impedance analysis (BIA) and categorized based on the recommendation of the Asian Working Group for Sarcopenia (AWGS). Frailty is established through a screening questionnaire based on the Cardiovascular Health Study. The study was chosen by simple random sampling and population register data.Results: The study involved 235 elderly people with 117 people in Pedawe village, 71 people in Mangupura village, 34 people in Serai village and 13 people in Songan village with a composition of 35.5% men and 64.5% women. In this study sarcopenia in women was 51% and men 49%, while frailty was experienced in 58.9% women and 41.02% men. The mean age is 67.7 years. The prevalence of total sarcopenia is 59% with the lowest percentage ranging from the villages of Mangupura (30%), Songan (53.8%), Pedawe (70.9%), and Serai (79.4%). The overall frailty prevalence in the four villages is 17% with the percentage starting from the lowest being Mangupura (1.4%), Serai (5.9%), Songan (22.2%) and Pedawe (29.1%).Conclusions: The prevalence of sarcopenia and frailty is most common among elderly women. The highest prevalence of sarcopenia was found in Serai village and frailty prevalence was highest in Pedawe village.Â Latar Belakang: Frailty ditandai dengan adanya penurunan fungsi fisiologis multi organ. Sarkopenia dan frailty memberikan dampak yang bermakna bagi individu dan bagi masyarakat sehingga perlu untuk mengetahui prevalensinya di masyarakat. Penelitian ini bertujuan untuk mengetahui prevalensi sarkopenia dan frailty di daerah pedesaanMetode: Penelitian menggunakan studi potong lintang pada populasi lansia di desa Pedawa, Mangupura, Serai dan Songan. Pengukuran massa otot menggunakan bioelectrical impedance analysis (BIA) dan dikategorikan berdasarkan rekomendasi Asian Working Group for Sarcopenia (AWGS). Frailty ditegakkan melalui kuesioner skrining berdasarkan Cardiovascular Health Study. Penelitian dipilih dengan cara simple random sampling dan data register penduduk.Hasil: Penelitian melibatkan 235 orang lanjut usia dengan jumlah 117 orang di desa Pedawe, 71 orang di desa Mangupura, 34 orang di desa Serai dan 13 orang di desa Songan dengan komposisi 35,5% laki-laki dan 64,5% perempuan. Pada penelitian ini sarkopenia pada perempuan adalah 51% dan laki-laki 49%, sedangkan frailty dialami 58,9% perempuan dan 41,02% laki-laki. Rerata usia adalah 67,7 tahun. Prevalensi sarkopenia total adalah 59% dengan persentase masing-masing mulai dari yang terendah adalah desa Mangupura (30%), Songan (53,8%), Pedawe (70,9%), dan Serai (79,4%).Â Prevalensi frailty keseluruhan di empat desa adalah 17% dengan persentase masing-masingÂ mulai dari yang terendah adalah desa Mangupura (1,4%), Serai (5,9%), Songan (22,2%) dan Pedawe (29,1%).Kesimpulan: Prevalensi sarkopenia dan frailty paling banyak ditemukan pada lansia perempuan. Prevalensi sarkopenia paling tinggi didapatkan di desa Serai dan prevalensi frailty didapatkan paling tinggi di desa Pedawe.

Evaluasi derajat delirium sebagai prediktor mortalitas pasien usia lanjut dengan delirium yang dirawat di RSUP Sanglah, Bali, Indonesia Dian Pritasari Jeger; Yosef Samon Sugi; I Gusti Putu Suka Aryana; RA Tuty Kuswardhani; I Nyoman Astika; Ida Bagus Putrawan; Ni Ketut Rai Purnami
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Delirium is an acute attention and cognitive disorder that occurs in elderly patients. The disorder is usually very serious, often goes unrecognized, and is usually fatal. Diagnosis requires a complete cognitive assessment and a history of acute symptoms. Despite the management of the cause, patients with delirium do not always recover. The aim of this study was to determine the correlation between the degree of delirium and the incidence of death in geriatric patients who were admitted to Sanglah General Hospital.Methods: A retrospective cohort study was conducted during November 2014-February 2015 of consecutive patients with delirium aged over 60 years. The degree of delirium was measured by the Memorial Delirium Assessment Scale (MDAS) and Charlson's-Age Comorbidity Index (CACI). These patients were followed periodically and then a bad outcome was determined, namely death while being treated. The association between the severity of delirium and clinical outcome was evaluated using the Pearson test. The results are said to be significant if the p value <0.05 on SPSS version 21 for Windows.Results: The prevalence of delirium in Sanglah General Hospital was mild delirium (48.4%), moderate delirium (28.1%), and severe delirium (23.4%). There was a significant difference in the prevalence of the degree of delirium based on age (p <0.05), but not on gender (p = 0.752). There was a significant difference in the incidence of death based on age (p = 0.045) and degree of delirium (p = 0.01). There was a moderate positive correlation between the degree of delirium and the incidence of death (p = 0.02; r = 0.373).Conclusion: There is a significant relationship between the degree of delirium and the incidence of death in geriatric patients hospitalized in Sanglah General Hospital. Latar belakang: Delirium merupakan gangguan perhatian dan kognitif akut yang terjadi pada pasien usia tua. Gangguan tersebut biasanya sangat serius, sering tidak dikenali, dan biasanya sangat fatal. Penegakan diagnosis memerlukan penilaian kognitif yang lengkap dan riwayat adanya gejala yang timbul secara akut. Meskipun diberikan penatalaksanaan terhadap penyebabnya, pasien dengan delirium tidak selalu pulih. Tujuan dari penelitian ini adalah untuk menentukan korelasi antara derajat delirium dengan insiden kematian pada pasien geriatri yang dirawat di RSUP Sanglah.Metode: Penelitian kohort retrospektif dilakukan selama bulan November 2014-Februari 2015 terhadap pasien dengan delirium yang berusia di atas 60 tahun secara konsekutif. Derajat delirium diukur dengan Memorial Delirium Assesment Scale (MDAS) dan Charlson’s-Age Comorbidity Index (CACI). Pasien tersebut diikuti secara berkala kemudian ditentukan luaran yang buruk yaitu kematian saat dirawat. Hubungan antara derajat keparahan delirium dengan luaran klinis dievaluasi menggunakan uji Pearson. Hasil dikatakan bermakna apabila nilai p<0.05 pada SPSS versi 21 untuk Windows.Hasil: Prevalensi delirium di RSUP Sanglah yakni delirium ringan (48,4%), delirium sedang (28,1%), dan delirium berat (23,4%). Terdapat perbedaan bermakna prevalensi derajat delirium berdasarkan umur (p<0,05), namun tidak pada jenis kelamin (p=0,752). Terdapat perbedaan bermakna pada insiden kematian berdasarkan umur (p=0,045) dan derajat delirium (p=0,01). Terdapat korelasi positif sedang antara derajat delirium dengan insiden kematian (p=0,02; r=0,373).Kesimpulan: Terdapat hubungan yang signifikan antara derajat delirium dengan insiden kematian pada pasien geriatri yang dirawat di RSUP Sanglah.

Co-Authors A Santoso AAG Budhiart Anak Agung Ayu Ratih Hapsari Anak Agung Mas Putrawati Triningrat Anak Agung Wiradewi Lestari Cilik Wiryani Dian Pritasari Jeger Hendra P. Setiawan I Gede Agus Sastrawan I Gede Risnawan Suastika Ardanayasa I Gusti Agung Wilaja Putra I Ketut Suastika I Made Jawi I Nyoman Astika I Nyoman Wande I Nyoman Wande I Putu Gede Adiatmika I Wayan Losen Adnyana I. N. Astika I.D. G.A.E. Putra Ida Ayu Pradnya Paramita Ida Bagus Putu Putrawan IN Astika IW Yuna Ariawan Jovita Secunda Ludirdja Juniarta, Pande Made K Andriyasa K Widana Katrin Kurniawan Leonard Kencana MADE RATNA SARASWATI . Michelle Prinka Adyana N Astika N. K.S. Diniari Ngakan Ketut Wira Suastika, Ngakan Ketut Wira Ni Ketut Rai Purnami Ni Made Ayu Sintya D Ni Made Putri Suastari Njoto, Edwin Nugroho Nym Astika Pande K. A. Prayudi Pande Nyoman Bayu Tirtayasa Putu A.T Adiputra Putu Shely Prihastuti Rudy R. A.T. Kuswardhani RA Tuty Kusumawardhani Richard Samsudin Semaradana, Wayan Giri Putra Sri Kayati Widyastuti Surya Rini, Sandra Tuty Kuswardani Wayan Giri Putra Wirawan, I Made Budi Yanson - Yosef Samon Sugi Yulan Permatasari

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