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All Journal Indonesian Journal of Pharmaceutical and Clinical Research Journal of Experimental and Clinical Pharmacy (JECP) Usadha Journal of Pharmacy
Mahendra, Andika Dwi
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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The Comparison of Antioxidant Activity of Ethanol Extract of Fruit, Seeds and Leaves of Yellow Pumpkin (Cucurbita moschata D.) using the DPPH (2,2-Diphenyl-1-Picrylhydrazyl) Method Rahmatillah, Annie; Rohmana, Vivin Marwiyati; Mahendra, Andika Dwi; Puspita Sari, Mawar Dela; 'Arifah, Zainul
Journal of Experimental and Clinical Pharmacy (JECP) Vol 5, No 1 (2025): February 2025
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v5i1.1317

Abstract

Yellow pumpkin (Cucurbita moschata D.) has various compounds that can be used as antioxidants, such as tocopherol, carotene, and phenolics. This research aims to determine which parts of the plant have potential as antioxidants by comparing the antioxidant activity of fruit, leaves, and seeds. Antioxidant activity measurements were carried out using the DPPH method by comparing the absorbance of the control and the absorbance of the sample to determine the percentage of antioxidant activity and IC50 value of each sample. From the measurement results, the IC50 values for pumpkin leaves, seeds, and fruit were 182.85 ppm, 57.04 ppm, and 90.88 ppm, respectively. Based on these results, leaves have the highest antioxidant activity compared to seeds and fruit. The results of this study show that pumpkin fruit and seeds have lower antioxidant activity than leaves. The results of this study show that pumpkin leaves had lower antioxidant activity than seeds and flesh.
Antibiotic Use in Cesarean Section and Hysterectomy Procedure: Qualitative and Quantitative Assessment Mahendra, Andika Dwi
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 4 No. 2 (2021): Indonesian Journal of Pharmaceutical and Clinical Research (IDJPCR) Vol. 04, No
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v4i2.6235

Abstract

Antibiotic resistance is global issue and the incident is increasing with the use of unwise antibiotic. This study is to describe and evaluate appropriateness of antibiotic prophylaxis selection on Cesarean Section and Hysterectomy procedure. Purpose of study is to evaluate appropiateness of antibiotic selection on cesarean section and hysterectomy. A retrospective study was performed during September 2016 - January 2017 in Private Hospital, Semarang. Data were analized quantitatively using ATC-DDD methodology. Evaluation of antibiotic prophylaxis will be assessed based on The guideline of The American College of Obstetricians and Gynecologists (ACOG) : Antibiotic Prophylaxis for Gynecologic Procedures and The American Society of Health-System Pharmacists (ASHP) : Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery. Overall, 90 of 95 patients were given antibiotic prophylaxis. The most frequently used antibiotics were ceftriaxone (69.51 DDD/Patient-days) and ceftazidime (14.95 DDD/Patient-days). Appropriate antibiotic selection based on the guidelines for cesarean section procedure was 1.75% and 6.1% for hysterectomy procedure. The use of antibiotic prophylaxis on cesarean section and hysterectomy procedure was very high and less appropriate in the selection. Almost patient received third-generation cephalosporin instead of first-generation cephalosporin such as cefazolin. cefazolin is more effective and narrow spectrum for infection-causing bacteria of these procedures.
BIOMARKER DISCOVERIES AND POTENTIAL BIOMARKERS IN LUNG CANCER : A NARRATIVE REVIEW Mahendra, Andika Dwi; Prabowo, Muhammad Hatta; Prawiningrum, Aisyah Fitriannisa
Usadha Journal of Pharmacy Vol. 2 No. 4 (2023): November
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v2i4.167

Abstract

Lung cancer is the second most common cause of death worldwide after breast cancer. This is associated with late diagnosis, which reduces the survival rate. Early diagnosis is one approach that may be employed to improve outcome for the patient with lung cancer. When a small level of cancer is present in the body, a biomarker can be utilized as a diagnostic marker. Liquid biopsy is minimal invasive which can be done to obtain multi-biomarkers in lung cancer. In this article, we will discuss and explore about potential biomarkers for lung cancer early diagnosis.
Co-Authors 'Arifah, Zainul Prabowo, Muhammad Hatta Prawiningrum, Aisyah Fitriannisa Puspita Sari, Mawar Dela Rahmatillah, Annie Rohmana, Vivin Marwiyati