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All Journal Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Farmasi Sains dan Komunitas Jurnal Pengabdian UntukMu NegeRI Jurnal Pengabdian Pada Masyarakat JPSCR : Journal of Pharmaceutical Science and Clinical Research Bubungan Tinggi: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Pada Masyarakat

Sholichah Rohmani

Farmasi Sekolah Vokasi Universitas Sebelas Maret

Author-ID : 2387478

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STUDY OF KINETICS MODEL OF FLAVONOID TOTAL RELEASE IN PATCH OF ANTIHYPERTENSIVE HERBS Dian Eka Ermawati; Anif Nur Artanti; Dyah Ayu Ambarwati; Niken Rosyana Dewi Septini; Sholichah Rohmani; Wisnu Kundarto
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 18, No 1 (2021)
Publisher : Sanata Dharma University

The liquid extract of antihypertensive herbs could reduce blood pressure equivalent to Hydrochlorothiazide 25 mg based on research conducted in “Hortus Medicus” clinic, Tawangmangu, Central Java, but parameters of herbal medicine taste, design, and packaging had the lowest scores. Transdermal patch was chosen as an alternative to resolve those problems. Polymers determined the effectiveness of the active substance release from the formula. Patch was formulated from combination of hydrophilic hydroxy methylcellulose (HPMC) and carboxymethylcellulose natrium (CMC-Na) polymer which would produce a fast release profile. The objective of this research was to study the kinetics models of total flavonoid release and to study the total number of flavonoids released from the antihypertensive herbs patch for 5 hours, as well as to determine the optimum formula for observing the weight, pH and loss on drying. Herbs were infused with distilled water at 90 ° C for 15 minutes, filtered then evaporated. Release kinetics model used a modified type-5 dissolution apparatus equipment with a cellophane membrane. The optimum proportion of HPMC and CMC-Na was 220:180 mg. Patch was dark brown, circle shaped, moist and flexible. It had pH value of 7.29 ± 0.09, folding endurance of 350, and thickness of 0.64 ± 0.05 mm. The average percentage of total flavonoids released from the matrix patch was 37.23% for 5 hours. The release kinetics followed the Higuchi kinetics model with a diffusion mechanism.

Pendampingan Pembuatan Hand Sanitizer Aroma Minyak Atsiri Sebagai Penunjang Pembelajaran Luring Di SMP Muhammadiyah 1 Prambanan Wisnu Kundarto; Dian Eka Ermawati; Muhammad Fiqri Zulpadly; Heru Sasongko; Sholichah Rohmani; Anif Nur Artanti; Daswati Rofiatun Sahifah
Jurnal Pengabdian UntukMu NegeRI Vol 5 No 2 (2021): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v5i2.3085

The schools have been allowed for doing face-to-face learning process with many requirements.Making own hand sanitizer will help schools to keep applying health protocol beside washing hands. Essential oils have been trusted for a long time give a calm effect and reduce stres. This activity have purpose to assistance hand sanitizer production with essential oils fragrance at SMP Muhammadiyah 1 Prambanan Yogyakarta. Knowledge have been transfered by team followed with demo and training to produce hand sanitizer with lemongrass fragrance at first activity. Knowledge score was determined from pre-test and post test answer score from multiple choice questions about hand sanitizer. Follow up became the next activity to ensure school can make their own hand sanitizer independently. The result showed knowledge score was increased from 52,11 to 92,11. School also have been made hand sanitizer independently with another essential oil varians. This products were limited used for school. Communication between team and school still continues.

Pemberdayaan Masyarakat melalui Wirausaha Kerupuk Bonggol Pisang di Kabupaten Sukoharjo Sholichah Rohmani; Adi Yugatama
Agrokreatif: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 5 No. 2 (2019): Agrokreatif Jurnal Ilmiah Pengabdian Kepada Masyarakat
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agrokreatif.5.2.103-108

One effort that can be done by housewives is entrepreneurship to make crackers. Food products from banana trees were chosen because they have good prospects, besides the fruit there are other parts that can be used, namely banana humps. Because of the benefits and high nutritional content, it is necessary to diversify from banana humps to be sold. The purpose of this activity is to inspire partners about the idea and spirit of entrepreneurship using sources of raw materials that are easy to obtain, so they can increase income. The program is carried out through two stages, namely processing banana humps into healthy crackers and transferring packaging technology. This activity was carried out in the training and development of technology for processing banana humps into cracker products, which could be an alternative economic new business in the community. The positive impact of this activity is the increasing skills and knowledge of partners about making food from banana trees, as well as improving the skills of packaging techniques. There is an increase in the ability of entrepreneurial partners in producing and selling products.

Menjaga Kualitas Jamu Kunyit Asam Segar Industri Rumah Tangga X Yogyakarta dengan Penyimpanan Suhu yang Tepat Berdasarkan Kadar Kurkuminoid Dian Eka Ermawati; Villian Septiana; Wisnu Kundarto; Anif Nur Artanti; Sholichah Rohmani; Heru Sasongko
Jurnal Pengabdian Pada Masyarakat Vol 6 No 2 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202162.617

IMPROVING THE QUALITY OF FRESH ACID TURMERIC JAMU OF HOME INDUSTRY X AT THE RIGHT TEMPERATURE STORAGE BASED ON CURCUMINOID CONCENTRATION. Tamarind turmeric herbal medicine contains about 10% curcuminoids, consisting of: 1-5% curcumin, demectosicurcumin and bisdemethoxy-curcumin. Curcuminoids are a group of phenolic compounds as antibacterial, anticholesterol and antioxidants. Home Industry (IRT) X in Yogyakarta produces fresh turmeric and sour herbal medicine and is sold via delivery via an online application. Handling and storage at inappropriate temperatures can affect curcuminoid levels in herbal medicine, so it is necessary to do research on curcuminoid levels at various temperatures to provide information on IRT X in particular and herbal medicine manufacturers in general. Samples of herbal turmeric acid IRT X Yogyakarta stored at room temperature (25±2°C), refrigerator temperature (4±2°C), and freezer temperature (-10±2°C), analyzed the levels of curcuminoids on variations in storage temperature manually. quantitative method with UV-Vis Spectrophotometry. The analysis begins with the manufacture of standard curves and assays which are replicated three times. The results showed that curcuminoid levels were affected by storage temperature. Samples of herbal turmeric acid IRT X Yogyakarta which were analyzed by UV-Vis spectrophotometry method obtained a standard curve of y = 0.009x + 0.025 with a value of r = 0.997. The results of curcuminoid levels at room temperature were 4.74±0.13; refrigerator temperature 4.85±0.22; and freezer temperature 5.18±0.22. The optimum temperature in the handling and storage of the tamarind turmeric herbal medicine is at low temperatures, namely the refrigerator temperature and freezer temperature to maintain the curcuminoid content in the herbal medicine.

Uniformity Test Tablets Of Atorvastatin on the Market Using Ultraviolet Spectrophotometer Sholichah Rohmani; Adi Yugatama; Ahmad Ainurofiq; Fea Prihapsara; Felicitas Lady
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 2, No 1 (2017)
Publisher : Universitas Sebelas Maret

Atorvastatin is one of the first choice in the treatment of dyslipidemia associated with a decreased risk of cardiovascular disease. Drug patent expires in 2011. Currently in Indonesia circulated atorvastatin dosage tablet innovator , several trade names , and one generic. The purpose of this study was conducted to determine the quality of the preparation of atorvastatin market in Indonesia through tablet dosage uniformity test , so that the appropriate levels of drugs can provide the desired therapeutic effect.Uniformity tablet dosage form of atorvastatin is done by measuring the uniformity of tablet weight, and content uniformity was done using ultraviolet spectrophotometry in methanol at the maximum wavelength of 246.2 nm and their validity was tested on the value of LOD (limit of detection), and LOQ (limit of quantitation). One- Way ANOVA analyzis was their also conducted. The results showed that of the calculation data obtained , either in column A or column B that there is no deviation from the weight of the tablet , and based on the calculation of CV showed that all the tablets of atorvastatin in the market already qualified uniformity of weight as indicated by the value of CV < 5 %, and the levels atorvastatin tablet generic and tablets under the trade name meets the standard requirements of a tablet that in the range 90.0 % - 110.0 % of the amount listed on the label

ANALISIS FAKTOR INTERNAL-EKSTERNAL TERHADAP PENGELOLAAN OBAT DI INSTALASI FARMASI RSUD DR. MOEWARDI SURAKARTA Sholichah Rochmani; Achmad Fudholi; Lukman Hakim
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 1, No 1 (2016)
Publisher : Universitas Sebelas Maret

SWOT analysis is first step for formulating the strategic, to analyze the external and internal environmental factors. The purpose of this research is to analyze the external and internal environmental factors which influence pharmacy department, formulating the strategic management of the pharmacy department that can increase good works Pharmacy Department of RSUD Dr. Moewardi Surakarta .The method for the research is realized by collecting secondary data related to drugs management in pharmacy department, and then collect the primary data by conducting direct observation in the form of interview with Chief Pharmacy Department and distribute questionnaires to the doctor, officials, and patients. To determine the management of drug using the drug management indicators and to determine strengths, weaknesses, opportunities, and threats using SWOT analysis. The result showed that the internal environmental factor such as drug management in selection phase, selected drugs by DOEN is 6%. Procurement phase, the percentage of capital available along with all the used fund can only absorbs the average of 95,6% of the real total, percentage according to between planning with the fact to inappropriate drug 105,01%, and the average availability of medicine of 35 days. On distribution phase, the expired or damaged medicine out of the supported 0%. Use phase, showed by the waiting time for outpatient uncompounding prescription is 30,47 minutes and compounding prescription is 60,01 minutes. External environmental factors in pharmacy department such as opportunity: human resources in pharmacy department need to practical training, a good service in pharmacy department, drugs is complete; threats focused on existing hospitals in Surakarta, good services for customers quality, long waiting time for drug in pharmacy department. Pharmacy Department of RSUD Dr. Moewardi Surakarta was on the first quadrant. The strategy which can be used by Pharmacy Department of RSUD Dr. Moewardi Surakarta in this condition is to support the aggressive growing policy (growth oriented strategy).

Perbedaan Metode Penambahan Bahan Penghancur Secara Intragranular-Ekstragranular Terhadap Sifat Fisik Serta Profil Disolusi Tablet Ibuprofen Sholichah Rohmani; Hilda Rosyanti
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 4, No 2 (2019)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v4i2.33622

Amilum pro tablet (Amprotab) sebagai bahan penghancur memiliki kekuatan pada aksi kapiler yang akan menarik cairan ke dalam tablet dan diharapkan dapat mempercepat waktu hancur tablet sehingga mempermudah ibuprofen untuk melarut. Kecepatan hancurnya tablet ditentukan oleh posisi bahan penghancur. Secara intragranular tablet akan dipecah menjadi partikel penyusun. Sedangkan secara ekstragranular tablet akan dipecah menjadi granul. Penelitian ini bertujuan untuk mengetahui pengaruh metode penambahan bahan penghancur secara intragranular, ekstragranular dan kombinasinya terhadap sifat fisik dan profil disolusi tablet ibuprofen. Pembuatan tablet ibuprofen dilakukan dengan metode granulasi basah. Tablet formula 1 dibuat secara intragranular, formula 2 kombinasi intragranular-ekstragranular dengan perbandingan 50:50 dan formula 3 secara ekstragranular. Granul kering yang homogen kemudian diuji sifat fisik granul meliputi : waktu alir dan sudut diam. Kemudian dicetak dengan diberi tekanan kompresi yang sama. Evaluasi tablet meliputi keseragaman bobot, kekerasan, kerapuhan, waktu hancur, penetapan kadar dan disolusi. Hasil yang diperoleh dibandingkan dengan literatur standard dan dianalisis secara statistik. Hasil yang diperoleh menunjukan bahwa penambahan amprotab sebagai bahan penghancur secara intragranular dan ekstragranular dengan perbandingan konsentrasi yang berbeda mempengaruhi sifat fisik pada keseragaman bobot, kekerasan, kerapuhan dan waktu hancur serta profil disolusi tablet ibuprofen, tetapi tidak berpengaruh pada kadar ibuprofen yang terkandung dalam tablet. Formula tablet yang baik yaitu F2 karena menghasilkan tablet yang memenuhi semua syarat uji sifat fisik tablet dan profil disolusi tablet ibuprofen.

Pelatihan Pemanfaatan Minyak Atsiri sebagai Bahan Aktif Balsam Aromaterapi kepada Warga Kelurahan Mojosongo M Fiqri Zulpadly; Dian Eka Ermawati; Heru Sasongko; Anif Nur Artanti; Sholichah Rohmani; Wisnu Kundarto; Diyah Tri Utami
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 4, No 4 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v4i4.6684

Pandemi Covid-19 yang melanda hampir seluruh negara di dunia khususnya di Indonesia membuat banyak masyarakat cemas, stres, dan frustasi akibat ketidakpastian dari berbagai aspek kehidupan. Stres pada umumnya merupakan kondisi normal dan tidak menimbulkan masalah pada kesehatan. Balsam aromaterapi dengan bahan utama dari minyak atsiri dapat digunakan sebagai alternatif untuk dapat merelaksasikan tubuh serta berperan dalam pengaturan emosional. Pengabdian kepada masyarakat ini adalah transfer pengetahuan dan pendampingan pelatihan pembuatan balsam aromaterapi. Kegiatan yang dilakukan mencakup pemberian informasi terkait pembuatan balsam yang dilanjutkan dengan demo pelatihan pembuatan balsam aromaterapi. Kegiatan pengabdian yang dilaksanakan pada tanggal 25 Oktober 2022 menghasilkan sebuah produk balsam aromaterapi hasil karya tangan para warga yang turut hadir yang didampingi oleh tim dari D3 Farmasi UNS. Kegiatan ini telah mencapai sasaran yang diinginkan yaitu kemampuan warga Kelurahan Mojosongo dalam membuat suatu produk skala kecil menengah namun memiliki nilai yang tinggi baik dari aspek guna maupun finansial. Kegiatan pendampingan ini merupakan langkah awal dalam membentuk kemandirian masyarakat setempat untuk memproduksi balsam aromaterapi secara mandiri ataupun kelompok yang berada dalam lingkup UMKM.The Covid-19 pandemic that hit almost all countries, especially in Indonesia, made many people anxious, stressed, and frustrated due to the uncertainty of various aspects of life. Stress is generally a normal condition and does not cause health problems. Aromatherapy balms with the main ingredients of essential oils can be used as an alternative to relax the body and play a role in emotional regulation. This community service is the transfer of knowledge and assistance in training on making aromatherapy balm. The activities included providing information on making balm, followed by a training demonstration on aromatherapy balm. The service activity, carried out on October 25, 2022, resulted in an aromatherapy balm product that was handmade by the present residents, accompanied by a team from UNS Pharmacy D3. This activity has achieved the desired target, namely the ability of the residents of Mojosongo Village to make a small-medium-scale product that has a high value both in terms of use and finances. This mentoring activity is the first step in establishing the independence of the local community to produce aromatherapy balm independently or in groups within the scope of Micro Small and Medium Enterprises (MSME).

Peningkatan Pengetahuan Masyarakat dengan Pendampingan Formulasi Handsanitizer Standar WHO di Kelurahan Mojosongo, Surakarta Dian Eka Ermawati; Anif Nur Artanti; Sholichah Rohmani; Wisnu Kundarto
Jurnal Pengabdian Pada Masyarakat Vol 7 No 3 (2022): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

INCREASING PUBLIC KNOWLEDGE WITH ASSISTANCE IN WHO STANDARD HANDSANITIZER FORMULATION IN MOJOSONGO VILLAGE, SURAKARTA. The Applied Pharmacy Research Group has a service roadmap that examines medicinal products, supplements, cosmetic and traditional medicines that can contribute and be adopted by society. One of the issues is liquid dosage form formulation. Alcohol is the one of choice after washing hands with soap. The use of hand sanitizer can deactivate microorganisms that stick to hand. This increase in use because pandemic covid-19 that made many people take preventive action. One way to prevent the spread of the Corona virus is maintain cleanliness such as diligently washing hands with soap and water. In the other hand the use of handsanitizer is also recommended when you cannot reach water and soap. Activity community service in Mojosongo Village, focuses on increasing public knowledge in formulate liquid Handsanitizer that is practical and simple according to the standards requirment by WHO (World Health Organization). The results of the questionnaire conducted before and after assistance in making hand sanitizers stated that most of the respondents had showed an increase in knowledge related to components in the manufacture of handsanitizers

Co-Authors Achmad Fudholi Ahmad Ainurofiq Anif Nur Artanti, Anif Nur Daswati Rofiatun Sahifah Diyah Tri Utami Dyah Ayu Ambarwati ERMAWATI, DIAN EKA Fea Prihapsara Felicitas Lady Heru Sasongko Heru Sasongko Hilda Rosyanti Lukman Hakim M Fiqri Zulpadly Muhammad Fiqri Zulpadly Niken Rosyana Dewi Septini Villian Septiana Wisnu Kundarto Wisnu Kundarto Wisnu Kundarto

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