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All Journal Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Farmasi Sains dan Komunitas Jurnal Pengabdian Pada Masyarakat Bubungan Tinggi: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Pada Masyarakat Proceeding of The International Conference on Health Sciences and Nursing
Sholichah Rohmani
Farmasi Sekolah Vokasi Universitas Sebelas Maret
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STUDY OF KINETICS MODEL OF FLAVONOID TOTAL RELEASE IN PATCH OF ANTIHYPERTENSIVE HERBS Dian Eka Ermawati; Anif Nur Artanti; Dyah Ayu Ambarwati; Niken Rosyana Dewi Septini; Sholichah Rohmani; Wisnu Kundarto
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 18, No 1 (2021)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.804 KB) | DOI: 10.24071/jpsc.002203

Abstract

The liquid extract of antihypertensive herbs could reduce blood pressure equivalent to Hydrochlorothiazide 25 mg based on research conducted in “Hortus Medicus” clinic, Tawangmangu, Central Java, but parameters of herbal medicine taste, design, and packaging had the lowest scores. Transdermal patch was chosen as an alternative to resolve those problems. Polymers determined the effectiveness of the active substance release from the formula. Patch was formulated from combination of hydrophilic hydroxy methylcellulose (HPMC) and carboxymethylcellulose natrium (CMC-Na) polymer which would produce a fast release profile. The objective of this research was to study the kinetics models of total flavonoid release and to study the total number of flavonoids released from the antihypertensive herbs patch for 5 hours, as well as to determine the optimum formula for observing the weight, pH and loss on drying. Herbs were infused with distilled water at 90 ° C for 15 minutes, filtered then evaporated. Release kinetics model used a modified type-5 dissolution apparatus equipment with a cellophane membrane. The optimum proportion of HPMC and CMC-Na was 220:180 mg. Patch was dark brown, circle shaped, moist and flexible. It had pH value of 7.29 ± 0.09, folding endurance of 350, and thickness of 0.64 ± 0.05 mm. The average percentage of total flavonoids released from the matrix patch was 37.23% for 5 hours. The release kinetics followed the Higuchi kinetics model with a diffusion mechanism.
Pemberdayaan Masyarakat melalui Wirausaha Kerupuk Bonggol Pisang di Kabupaten Sukoharjo Sholichah Rohmani; Adi Yugatama
Agrokreatif: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 5 No. 2 (2019): Agrokreatif Jurnal Ilmiah Pengabdian Kepada Masyarakat
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agrokreatif.5.2.103-108

Abstract

One effort that can be done by housewives is entrepreneurship to make crackers. Food products from banana trees were chosen because they have good prospects, besides the fruit there are other parts that can be used, namely banana humps. Because of the benefits and high nutritional content, it is necessary to diversify from banana humps to be sold. The purpose of this activity is to inspire partners about the idea and spirit of entrepreneurship using sources of raw materials that are easy to obtain, so they can increase income. The program is carried out through two stages, namely processing banana humps into healthy crackers and transferring packaging technology. This activity was carried out in the training and development of technology for processing banana humps into cracker products, which could be an alternative economic new business in the community. The positive impact of this activity is the increasing skills and knowledge of partners about making food from banana trees, as well as improving the skills of packaging techniques. There is an increase in the ability of entrepreneurial partners in producing and selling products.
Menjaga Kualitas Jamu Kunyit Asam Segar Industri Rumah Tangga X Yogyakarta dengan Penyimpanan Suhu yang Tepat Berdasarkan Kadar Kurkuminoid Dian Eka Ermawati; Villian Septiana; Wisnu Kundarto; Anif Nur Artanti; Sholichah Rohmani; Heru Sasongko
Jurnal Pengabdian Pada Masyarakat Vol 6 No 2 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202162.617

Abstract

IMPROVING THE QUALITY OF FRESH ACID TURMERIC JAMU OF HOME INDUSTRY X AT THE RIGHT TEMPERATURE STORAGE BASED ON CURCUMINOID CONCENTRATION. Tamarind turmeric herbal medicine contains about 10% curcuminoids, consisting of: 1-5% curcumin, demectosicurcumin and bisdemethoxy-curcumin. Curcuminoids are a group of phenolic compounds as antibacterial, anticholesterol and antioxidants. Home Industry (IRT) X in Yogyakarta produces fresh turmeric and sour herbal medicine and is sold via delivery via an online application. Handling and storage at inappropriate temperatures can affect curcuminoid levels in herbal medicine, so it is necessary to do research on curcuminoid levels at various temperatures to provide information on IRT X in particular and herbal medicine manufacturers in general. Samples of herbal turmeric acid IRT X Yogyakarta stored at room temperature (25±2°C), refrigerator temperature (4±2°C), and freezer temperature (-10±2°C), analyzed the levels of curcuminoids on variations in storage temperature manually. quantitative method with UV-Vis Spectrophotometry. The analysis begins with the manufacture of standard curves and assays which are replicated three times. The results showed that curcuminoid levels were affected by storage temperature. Samples of herbal turmeric acid IRT X Yogyakarta which were analyzed by UV-Vis spectrophotometry method obtained a standard curve of y = 0.009x + 0.025 with a value of r = 0.997. The results of curcuminoid levels at room temperature were 4.74±0.13; refrigerator temperature 4.85±0.22; and freezer temperature 5.18±0.22. The optimum temperature in the handling and storage of the tamarind turmeric herbal medicine is at low temperatures, namely the refrigerator temperature and freezer temperature to maintain the curcuminoid content in the herbal medicine.
Pelatihan Pemanfaatan Minyak Atsiri sebagai Bahan Aktif Balsam Aromaterapi kepada Warga Kelurahan Mojosongo M Fiqri Zulpadly; Dian Eka Ermawati; Heru Sasongko; Anif Nur Artanti; Sholichah Rohmani; Wisnu Kundarto; Diyah Tri Utami
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 4, No 4 (2022)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v4i4.6684

Abstract

Pandemi Covid-19 yang melanda hampir seluruh negara di dunia khususnya di Indonesia membuat banyak masyarakat cemas, stres, dan frustasi akibat ketidakpastian dari berbagai aspek kehidupan. Stres pada umumnya merupakan kondisi normal dan tidak menimbulkan masalah pada kesehatan. Balsam aromaterapi dengan bahan utama dari minyak atsiri dapat digunakan sebagai alternatif untuk dapat merelaksasikan tubuh serta berperan dalam pengaturan emosional. Pengabdian kepada masyarakat ini adalah transfer pengetahuan dan pendampingan pelatihan pembuatan balsam aromaterapi. Kegiatan yang dilakukan mencakup pemberian informasi terkait pembuatan balsam yang dilanjutkan dengan demo pelatihan pembuatan balsam aromaterapi. Kegiatan pengabdian yang dilaksanakan pada tanggal 25 Oktober 2022 menghasilkan sebuah produk balsam aromaterapi hasil karya tangan para warga yang turut hadir yang didampingi oleh tim dari D3 Farmasi UNS. Kegiatan ini telah mencapai sasaran yang diinginkan yaitu kemampuan warga Kelurahan Mojosongo dalam membuat suatu produk skala kecil menengah namun memiliki nilai yang tinggi baik dari aspek guna maupun finansial. Kegiatan pendampingan ini merupakan langkah awal dalam membentuk kemandirian masyarakat setempat untuk memproduksi balsam aromaterapi secara mandiri ataupun kelompok yang berada dalam lingkup UMKM.The Covid-19 pandemic that hit almost all countries, especially in Indonesia, made many people anxious, stressed, and frustrated due to the uncertainty of various aspects of life. Stress is generally a normal condition and does not cause health problems. Aromatherapy balms with the main ingredients of essential oils can be used as an alternative to relax the body and play a role in emotional regulation. This community service is the transfer of knowledge and assistance in training on making aromatherapy balm. The activities included providing information on making balm, followed by a training demonstration on aromatherapy balm. The service activity, carried out on October 25, 2022, resulted in an aromatherapy balm product that was handmade by the present residents, accompanied by a team from UNS Pharmacy D3. This activity has achieved the desired target, namely the ability of the residents of Mojosongo Village to make a small-medium-scale product that has a high value both in terms of use and finances. This mentoring activity is the first step in establishing the independence of the local community to produce aromatherapy balm independently or in groups within the scope of Micro Small and Medium Enterprises (MSME).
Peningkatan Pengetahuan Masyarakat dengan Pendampingan Formulasi Handsanitizer Standar WHO di Kelurahan Mojosongo, Surakarta Dian Eka Ermawati; Anif Nur Artanti; Sholichah Rohmani; Wisnu Kundarto
Jurnal Pengabdian Pada Masyarakat Vol 7 No 3 (2022): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (515.791 KB) | DOI: 10.30653/002.202273.54

Abstract

INCREASING PUBLIC KNOWLEDGE WITH ASSISTANCE IN WHO STANDARD HANDSANITIZER FORMULATION IN MOJOSONGO VILLAGE, SURAKARTA. The Applied Pharmacy Research Group has a service roadmap that examines medicinal products, supplements, cosmetic and traditional medicines that can contribute and be adopted by society. One of the issues is liquid dosage form formulation. Alcohol is the one of choice after washing hands with soap. The use of hand sanitizer can deactivate microorganisms that stick to hand. This increase in use because pandemic covid-19 that made many people take preventive action. One way to prevent the spread of the Corona virus is maintain cleanliness such as diligently washing hands with soap and water. In the other hand the use of handsanitizer is also recommended when you cannot reach water and soap. Activity community service in Mojosongo Village, focuses on increasing public knowledge in formulate liquid Handsanitizer that is practical and simple according to the standards requirment by WHO (World Health Organization). The results of the questionnaire conducted before and after assistance in making hand sanitizers stated that most of the respondents had showed an increase in knowledge related to components in the manufacture of handsanitizers
Phytochemical Screening for Phenol and Optimizing the SNEDDS (Self-Nanoemulsifying Drug Delivery System) Formula Using the Simplex Lattice Design Method on Curcuma caesia Roxb Rhizome Extract Sholichah Rohmani; Okid Parama Astirin; Soerya Dewi Marliyana; Nestri Handayani
Proceeding of the International Conference on Health Sciences and Nursing Vol. 1 No. 2 (2024): December : Proceeding of the International Conference on Health Sciences and Nu
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ichsn.v1i2.33

Abstract

This research aims to screen the phytochemistry of phenol and optimize the formulation of Curcuma caesia Roxb. rhizome extract, which is difficult to dissolve in water, in the form of Self-Nanoemulsifying Drug Delivery System (SNEDDS) using the simplex lattice design method. The phenol content was identified using thin-layer chromatography,and the compound levels were determined spectrophotometrically. An initial screening was conducted to determine the oil phase, surfactant, and co-surfactant to use. The characterization of SNEDDS in the optimal formula includes transmittance, particle size, and polydispersity-index (PI). Olive oil, Tween 80,and polyethyleneglycol (PEG)-400 are the oil phase, surfactant, and co-surfactant selected due to the highest ability to dissolve Curcuma caesia Roxb.rhizome extract. The results of phytochemical screening of the polyphenol compound group using thin-layer chromatography produced spots with an Rf value of 0.76 and a phenol content of 61.823 mgGAE/g. The optimization results showed that the optimal formula was obtained at a composition of 1:8:1 for olive oil, Tween 80, and PEG-400. The SNEDDS of C.caesia Roxb.rhizome extract produced a nanoemulsion with a loading dose of 250 mg/5 g SNEDDS, a transmittance of 98.6%, a particle size of 14.1 nm, and a polydispersity index (PI) of 0.363.
Co-Authors Achmad Fudholi Ahmad Ainurofiq Anif Nur Artanti, Anif Nur Diyah Tri Utami Dyah Ayu Ambarwati ERMAWATI, DIAN EKA Fea Prihapsara Felicitas Lady Heru Sasongko Hilda Rosyanti Lukman Hakim M Fiqri Zulpadly Nestri Handayani Niken Rosyana Dewi Septini Okid Parama Astirin Soerya Dewi Marliyana Villian Septiana Wisnu Kundarto Wisnu Kundarto