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All Journal Jurnal Farmasi Higea Jurnal Analis Medika Biosains (JAMBS) SANITAS: Jurnal Teknologi dan Seni Kesehatan Journal of Nursing and Public Health (JNPH) Proceeding of Bengkulu International Conference on Health
Zamharira Muslim
Poltekkes Kemenkes Bengkulu
Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Perbedaan Kadar Protein Urin Sebelum Dan Sesudah Latihan Fisik Pada Atlet di Pusat Pendidikan dan Latihan Pelajar (PPLP) Provinsi Bengkulu Jon Farizal; Zamharira Muslim; Nadia Wulan Syapera
Jurnal Analis Medika Biosains (JAMBS) Vol 7, No 1 (2020): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (141.267 KB) | DOI: 10.32807/jambs.v7i1.155

Abstract

Latar belakang: Latihan fisik dengan intensitas berat mengakibatkan sel-sel otot rangka bekerja lebih giat, dan oksigen yang dibutuhkan sel semakin meningkat sehingga otot rangka mengalami vasodilatasi. Sedangkan di ginjal mengalami vasokontriksi, aliran darah berkurang sampai 20% sehingga dapat menyebabkan ekskresi protein > 1,5 mg/min. protein urin adalah pemeriksaan penunjang fungsi ginjal. Data menunjukkan bahwa 70-80% atlet mengalami proteinuria setelah olahraga intensitas berat, baik pada atlet olahraga kontak maupun non-kontak.Tujuan: untuk mengetahui perbedaan kadar protein urin sebelum dan sesudah latihan fisik. Metode: Penelitian yang digunakan adalah pra eksperimen dengan rancangan one group pretest postest. Sampel terdiri dari 31 responden dengan metode total sampling. Dilakukan pengukuran kadar protein urin, diberi perlakuan latihan fisik dan diukur kembali kadar protein urinnya  dengan metode pemeriksaan asam asetat 6%. Analisis data menggunakan uji Wilcoxon.Hasil: terdapat peningkatan kadar protein urin dengan nilai rerata sebelum latihan fisik sebesar 0,03 dan nilai rerata sesudah latihan fisik 0,19, namun tidak terdapat perbedaan yang signifikan kadar protein urin sebelum dan sesudah latihan fisik dengan P=0,059. Kesimpulan: Tidak Terdapat perbedaan yang signifikan kadar protein urin sebelum dan sesudah latihan fisik.
Prevalensi Penyimpanan Antibiotik Di Rumah Tangga Kecamatan Teluk Segara Kota Bengkulu Zamharira Muslim; Riska Anggia Juita; Avrilya Iqoranny Susilo
Jurnal Farmasi Higea Vol 14, No 1 (2022)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v14i1.432

Abstract

Penyimpanan obat-obatan yang umumnya dilakukan di rumah tangga memiliki tujuan tersendiri baik itu sedang digunakan ataupun untuk penggunaan di masa mendatang. Antibiotik yang masih banyak disimpan untuk digunakan sebagai swamedikasi dalam rumah tangga. Penyimpanan antibiotik dapat memicu penggunaan obat yang tidak rasional. Tujuan penelitian ini adalah untuk mengetahui tren penyimpanan antibiotik di masyarakat kecamatan Teluk Segara kota Bengkulu. Penelitian ini merupakan penelitian survey deskriptif, sampel diambil menggunakan teknik purposive sampling dengan metode wawancara. Hasil penelitian menunjukkan bahwa sebanyak 40 orang ibu rumah tangga menyimpan obat antibiotik. Antibiotik yang disimpan mayoritas jenis Amoxicillin (67,39%), sebagian besar memperoleh antibiotik tidak menggunakan resep dokter (57,50%) dan alasan masyarakat menyimpan antibiotik untuk antisipasi bila terjadi sakit dimasa mendatang (48,10%). Dari penelitian dapat disimpulkan bahwa penyimpanan antibiotik di masyarakat Bengkulu masih sangat tinggi.
Antibiotic Sensitivity Of Acute Respiratory Infection Patients In Bhayangkara Hospital Bengkulu. Zamharira Muslim; Putri Widelia Welkriana; Regita Pratiwi Mahardika
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 11 No 1 (2020): SANITAS Volume 11 Nomor 1 Tahun 2020
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2020.3

Abstract

The high incidence of antibiotic resistance in the treatment of infections today is very worrying. The main therapy in patients with acute respiratory infections (ARI) is using antibiotics. This study aims to determine the sensitivity of several antibiotics to the bacteria that cause ARI. The design of this study is quasi-experimental. This sensitivity testing uses the disc diffusion method (Kirby Bauer). The antibiotics used are Ampicillin and Cefotaxime. The results obtained are that the antibiotic Ampicillin resistant by 86.26% and 13.63% are still sensitive to the bacteria that causes ARI. The same thing also happened to Cefotaxime antibiotics, most of which were resistant (59.09%), intermediate (9.09%), and most were still sensitive (31.81%) to bacteria that infect the respiratory tract. From the results obtained it can be concluded that the incidence of bacterial resistance to ampicillin and cefotaxime is very high against bacteria that cause ARI.
Testing Effect Of Immunomodulator Ethanol Extract Of Mengkudu Leaves (Morinda Citrifolia) On Macrofag Cell Activities In Mencit Balb/C Infected Plasmodium Berghei Jon Farizal; Leni Marlina; Susiwati Susiwati; zamharira Muslim
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 11 No 2 (2020): SANITAS Volume 11 Nomor 2 Tahun 2020
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2020.23

Abstract

Background malaria fever is a disease that is still a problem in developing countries. Plasmodium bergheiis a facultative intracellular parasite, so the immune system that plays a role is the cellular system. Morinda citrifolia is a traditional medicinal plant that contains many active compounds that can reduce the number of malaria parasitemia. Proving the immunomodulatory effect of ethanol extract ofmorinda citrifolia on phagocytosis activity of Balb/c mice infected with Plasmodium berghei. The data were obtained from calculating the number of phagocytosis activity of macrophage cells in each field of view. A different test for macrophage phagocytosis using One Way ANOVA followed by Post Hoct Test. Method this type of research is experimental with the design of the post-test only control group design in experimental animals balb/c mice consisting of 24 male mice, divided into 4 groups. (K) is the control group given Aquabidest, and the treatment group (P1, P2, P3) which was given extract morinda citrifolia with stratified doses (0.64 mg / kgBb / day, 1.28 mg / kgBb / day, 2.56 mg / kgBb / day). The treatment process was given for 13 days and on the 6th day was infected with Plasmodium bergheias much as 0.1 ml x 106 intraperitoneally. On the 14th day, peritoneal fluid isolation was carried out followed by an examination of macrophage cell phagocytosis activity. Result ethanol extract Morinda citrifolia can increase macrophage phagocytosis, between control and treatment P1, P2, and P3 have significant differences, but between treatments, there is no significant difference. Conclusion. Ethanol extract of Morinda citrifolia in various doses can increase the phagocytosis of macrophages in Babl/c mice infected with Plasmodium berghei.
Resistance Test of Bacterial Causes of Urinary Tract Infection Against Ciprofloxacin and Ceftriaxone Antibiotics Zamharira Muslim; Aisyah Novrianti; Dira Irnameria
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 11 No 2 (2020): SANITAS Volume 11 Nomor 2 Tahun 2020
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2020.19

Abstract

Urinary Tract Infection (UTI) is an infection caused by bacteria in the urinary tract. UTI is the second infectious disease after respiratory infections with the highest number of cases of 8.3 million each year. The main therapy for UTIs is the use of antibiotics. However, at present there are many incidents of antibiotic resistance. This study aims to determine the sensitivity of antibiotics to bacteria that cause urinary tract infections. Sampling was taken using accidental sampling method and willing to fit the research context. The antibiotics tested were Ciprofloxacin and Ceftriaxone. The number of samples in this study was 18 samples with the finding of 15 Gram positive and 3 Gram negative samples after Gram staining. The results of the examination of the inhibition zone diameter of the ciprofloxacin antibiotic were mostly resistance (72.2%), a small proportion of intermediates (5.6%), and a small proportion were still sensitive (22.2%). Ceftriaxone antibiotic almost all (77.8%) resistance, a small proportion (5.6%) intermediates, a small proportion (16.7%) sensitive to urinary tract infections. From these results it can be concluded that the inhibition zone diameter of ciprofloxacin and ceftriaxone antibiotics is mostly resistant, so it is less effective for use in the treatment of urinary tract infections.
Simplicia Characterization And Phytochemical Screening Of Secondary Metabolite Compounds Ethanol Extract Of Trembesi Leaves (Samanea saman) Zamharira Muslim; Heti Rais Khasanah; Yopita Sari
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 12 No 2 (2021): SANITAS Volume 12 Nomor 2 Tahun 2021
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2021.12

Abstract

Trembesi plant (Samanea saman) is a plant that has the potential as traditional medicine. People in using medicinal plants often do not know the chemical content of these plants, so that in determining the amount of dosage, people only rely on experience and estimates. Research on the characterization of trembesi leaf simplicia has never been done. Research on the characterization of trembesi leaf simplicia has never been done. The purpose of this study was to determine the characteristics of trembesi leaf simplicia including specific and non-specific characteristics. The research is carried out in the form of experiments in the laboratory. The sample used is trembesi leaves. The research stages started from discovery, making simplicia, extraction, specific and non-specific characteristics. In the phytochemical test, ethanol extract of trembesi leaves was used. Data analysis used is descriptive method. Specific results showed trembesi leaf simplicia has a coarse powder form, distinctive odor, tasteless, green in color, and on microscopic results of trembesi leaf simplicia powder there is starch, fragments in the form of epidermis, water soluble extract content 11.93%, ethanol soluble essence 18, 93% and contains flavonoids, tannins, steroids and saponins. The results of non-specific characteristics are 8.07% water content, 7.91% ash content and 0.29% acid insoluble ash content.
Community Behavior Study Regarding Drug Purchases at Bengkulu City Pharmacies in 2021 Avrilya Iqoranny Susilo; Zamharira Muslim
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 13 No 1 (2022): SANITAS Volume 13 Nomor 1 Tahun 2022
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2022.4

Abstract

At this time the practice of self-medication or self-medication is increasingly being carried out by the community. This is done for various reasons, including feeling that the disease they are suffering from is only a minor illness that does not need to be treated by a doctor. This study aims to get a picture of people's behavior when searching for drugs at pharmacies in their self-medication practice in the Bengkulu City area. The research was conducted using a direct survey research method using observation sheets. Determination of the sample of pharmacies and respondents was done by using purposive sampling technique. People already have a choice of what medicine they will buy at the pharmacy to relieve the pain they feel (84.7%) and ask pharmacists for advice in making choices (15.3%). Most of the drugs used in the practice of self-medication by the community are brand-name drugs (81%) and a small percentage of people use generic drugs (19%). The choices in the use of drugs are over-the-counter drugs (21.4%), limited over-the-counter drugs (28.8%) and hard drugs (49.8%). Based on this, the behavior of people who go to pharmacies to practice self-medication, most of them already have a choice of what medicine they will buy to relieve the pain they feel. The thing that must be a concern is that many people choose to use hard drugs in their self-medication practice without asking for advice from pharmacists at the pharmacy (49.8%), while hard drugs in their use must use a doctor's prescription.
POLA PENGGUNAAN ANALGETIK-ANTIPIRETIK PADA PASIEN COVID-19 DI RSUD DR. M. YUNUS BENGKULU ZAMHARIRA MUSLIM; SANTY YULIANA BR SIMATUPANG; LINDA LINDA
Journal of Nursing and Public Health Vol 11 No 1 (2023)
Publisher : UNIVED Press, Universitas Dehasen Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37676/jnph.v11i1.4113

Abstract

Pendahuluan: Corona virus Disease 2019 (COVID-19) merupakan sebuah penyakit yang ditularkan oleh virus. Virus ini bernama virus sindrom pernafasan akut (SARS-COV-2). Virus ini dapat mempengaruhi secara signifikan system kardiovaskular seseorang. Dalam penanganan COVID-19, pedoman terapi menyatakan bahwa terapi dari terapi simtomatik sangat di butuhan, karena ia berguna untuk mengurangi gejala yang diderita oleh pasien, penanganan tersebut dapat berupa pemberian analgetik dan antipiretik. Penelitian ini bertujuan untuk mengetahui pola penggunaan analgetik-antipiretik pada pasien COVID-19 di RSUD Dr. M. Yunus kota Bengkulu. Metode Penelitian: Penelitian ini dilakukan dengan menggunakan rancangan penelitian deskriftif yang bersifat observasional dengan pendekatan cross sectional dan pengambilan data dilakukan secara retrospektif menggunakan data sekunder pada pasien COVID-19 di RSUD dr. M. Yunus kota Bengkulu pada Bulan Juni-September 2021. Hasil: Penggunaan analgetik-antipiretik pada pasien COVID-19 di RSUD dr. M. Yunus didapatkan bahwa Paracetamol Tablet dengan dosis 500mg adalah obat yang sering digunakan dengan persentase sebanyak 141 (61%). Kesimpulan : Berdasarkan hasil penelitian profil penggunaan analgetik-antipiretik pada pasien COVID-19 di RSUD dr. M. Yunus Kota Bengkulu pada Bulan Juni-September 2021 diperoleh bahwa pemberian Paracetamol tablet dengan dosis 500mg merupakan pemberian yang sering diberikan.
DESCRIPTION OF CURRENT BLOOD SUGAR LEVELS IN SCHIZOPHRENIC PATIENTS UNDERGOING ANTIPSYCHOTIC THERAPY AT RSKJ SOEPRAPTO BENGKULU Honesty Salma Junisa; Zamharira Muslim; Nadia Pudiarifanti
Proceeding B-ICON Vol. 2 No. 1 (2023): Proceeding of The 3rd Bengkulu International Conference on Health (B-ICON 2023)
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/bicon.v2i1.205

Abstract

One of the treatments for schizophrenia patients with pharmacology is antipsychotic treatment. Long-term use of antipsychotic drugs can cause side effects in very serious metabolic disorders, such as the risk of obesity, diabetes, and dyslipidemia. The purpose of this study was to determine the description of blood glucose levels during schizophrenia patients undergoing antipsychotic therapy at RSKJ Soeprapto Bengkulu. This research method is descriptive with retrospective data collection on medical records of schizophrenia patients at RSKJ Soeprapto Bengkulu for the period 2022. The number of samples used was 86 schizophrenia patients undergoing antipsychotic therapy. The results of this study showed that most patients were male 68 patients, the age range was 36-45 years old with 26 patients, the longest use of antipsychotic therapy was 2 years with 28 people (33%), the body mass index in schizophrenia patients was normal body mass index with 56 people. The most common single antipsychotic use was Risperidone for as many as 36 patients, for the use of the most combination antipsychotics, Chlorpromazine-Risperidone was 8 patients, and all patients had normal blood glucose levels (100%). This study concludes that blood glucose levels during schizophrenia patients who use single and combined antipsychotic therapy show no increase in blood glucose levels.
OVERVIEW OF ANTIBIOTIC USE USING ATC/DDD METHOD IN KUALA LEMPUING HEALTH CENTER, BENGKULU CITY, 2020-2021 Mitha Selpana; Zamharira Muslim; Avrilya Iqoranny Susilo
Proceeding B-ICON Vol. 2 No. 1 (2023): Proceeding of The 3rd Bengkulu International Conference on Health (B-ICON 2023)
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/bicon.v2i1.210

Abstract

The high use of antibiotics in every region of Indonesia causes a high possibility of irrational use of antibiotics. this study is to find out how the use of antibiotics using the ATC/DDD method is described at the Kuala Lempuing Health Center, Bengkulu City in 2020 and 2021. The type of research is descriptive in nature with a purposive sampling technique using the ATC/DDD method on outpatient prescriptions containing antibiotics. The results of this study showed The most widely used antibiotic is amoxicillin. The total value of DDD/1000 KPRJ at the Kuala Lempuing Health Center the total DDD/1000 KPRJ value during 2020 was 3873.4 and in 2021 it increased to 4591.3. This study concludes Amoxicillin is the most widely used antibiotic. The highest total value of DDD/1000 KPRJ at the Kuala Lempuing Health Center occurred in 2021.
Co-Authors Aisyah Novrianti Avrilya Iqoranny Susilo Heti Rais Khasanah Honesty Salma Junisa Irnameria, Dira Jon Farizal, Jon Leni Marlina Linda Linda Mitha Selpana Nadia Pudiarifanti Nadia Wulan Syapera Putri Widelia Welkriana Regita Pratiwi Mahardika Riska Anggia Juita SANTY YULIANA BR SIMATUPANG Susiwati Susiwati Yopita Sari