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All Journal Jurnal Media Analis Kesehatan Klinikal Sains (Jurnal Analis Kesehatan) Jurnal Analis Medika Biosains (JAMBS) Jaringan Laboratorium Medis
Tantri Analisawati Sudarsono
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Public Health

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Pengaruh Hemolisis Terhadap Nilai Trombosit Dengan Menggunakan Metode Direct Counting Nurmalita Putri Nugrahena; Tantri Analisawati Sudarsono; Linda Wijayanti
Jurnal Analis Medika Biosains (JAMBS) Vol 8, No 2 (2021): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v8i2.228

Abstract

Hemolisis yaitu pecahnya sel darah merah dan keluarnya hemoglobin ke plasma. Hemolisis dapat terjadi secara in vitro dan in vivo. Sampel yang hemolisis dapat mempengaruhi hasil pemeriksaan laboratorium yang dapat menyebabkan kesalahan diagnosis, terapi dan prevensi. Tujuan penelitian ini adalah untuk melihat pengaruh hemolisis terhadap nilai trombosit dengan menggunakan metode penghitungan serta penilaian trombosit dari sampel darah yang tidak lisis dan dilisiskan secara in vitro. Penelitian ini dilakukan secara eksperimental pada bulan Juli 2020 di Laboratorium Patologi Klinik Fakultas Kedokteran Universitas Muhammadiyah Purwokerto. Teknik pengambilan sampel dilakukan secara purposive sampling sebanyak 14 sampel.Perhitungan nilai trombosit dilakukan menggunakan metode penghitungan langsung.  
EFEK MONOSODIUM GLUTAMAT TERHADAP GAMBARAN HISTOLOGI HEPAR TIKUS PUTIH (Rattus norvegicus) GALUR WISTAR Shely Ayu Lestari; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono
Jurnal Media Analis Kesehatan Vol 12, No 1 (2021): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Poltekkes Kemenkes Pakassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mak.v12i1.2000

Abstract

Monosodium glutamate (MSG) is a sodium salt of glutamic acid that naturally comes from vegetable and animal protein functioned as a taste enhancer. So far, the use of MSG in various countries has increased by 1 g / day and can have an impact on cell damage to several organs. The purpose of this study was to find out the effects of MSG on the liver histology of Wistar white rats (Rattus norvegicus). This study used Posttest Only Control Group Design consisting of 4 groups, as control and MSG treatment doses of 5 g / kg BW, 10 g / kg BW, and 15 g / kg BW for 14 days orally. Each group consisted of 6 male white rats (Rattus norvegicus) aged 2-3 months with a weight of 200-250 grams in good health. A day after 14 days of treatment, the rats' liver organs were taken and preparations were made using the paraffin method. Data were analyzed using the Kruskal-Wallis test. The results of research showed that the control group looked normal, while the P1 group had 40.5 (40-43)% cell abnormalities and 52.5 (27-56)% cell abnormalities. The P3 group showed the most significant liver cell damage, namely 60 (59-62)%. The results of the Kruskal-Wallis test analysis showed a significant difference of p = 0.034 between cell abnormalities and the dose level of MSG (p-value 0.05). It can be concluded that MSG administration in stratified doses can cause liver cell damage in the form of degeneration and necrosis. Giving a dose of MSG 15 g / kg BW for 14 days showed the most significant liver cell damage at 60 (59-62)%.Keywords: Cell Abnormality, Liver, Monosodium Glutamate
Perbandingan Kadar Ureum Sebelum dan Sesudah Hemodialisis Pada Penderita Gagal Ginjal Kronik Imam Sudarso; Retno Sulistiyowati; Minto Rahaju; Tantri Analisawati Sudarsono
Jaringan Laboratorium Medis Vol 5, No 1 (2023): May 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i1.9161

Abstract

One of the body's organs, the kidney serves a vital purpose in the excretory and secretory systems. Excretion is the removal of waste products from the body's metabolism, and secretion is the release of chemicals and hormones that are involved in the metabolism of the body. Kidney failure is a condition brought on by kidney damage and is further broken down into acute and chronic forms. Long-lasting kidney damage carries a higher risk to one's health. Hemodialysis is a type of dialysis that helps the kidneys perform their normal functions by removing waste and toxic substances that build up in the blood. This study is analytical observational with a cross-sectional design and a sample of patients with chronic kidney failure at RSUD (Regional Public Hospital) dr. R. Goeteng Taroenadibrata Purbalingga. Non-probability sampling with a purposive sampling method was the sampling technique used. This study compared the urea levels in patients with chronic kidney failure before and after hemodialysis. According to the results of the study, there is a significant difference between urea levels before and after hemodialysis, which had a p-value of 0.003 (sig 0.05).
HUBUNGAN KEJADIAN HIPERTENSI DENGAN PROTEIN URINE PADA IBU HAMIL TRIMESTER III DI RSUD dr. SOEDIRMAN KEBUMEN: THE CORRELATION BETWEEN THE INCIDENCE OF HYPERTENSION AND URINE PROTEIN IN THIRD TRIMESTER PREGNANT WOMEN AT RSUD dr. SOEDIRMAN KEBUMEN Dwiar Apriyanti; Retno Sulistiyowati; Tantri Analisawati Sudarsono; Minto Rahaju
Klinikal Sains : Jurnal Analis Kesehatan Vol. 12 No. 1 (2024): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v12i1.4508

Abstract

Abstract The prevalence of hypertension during pregnancy is 2.6 - 7.3% of all pregnancy incidents which can have risks for pregnant women, which is usually called the Maternal Mortality Rate (AKI). Hypertension during pregnancy is one of the causes of maternal death which can be detected early through a urine protein test. Urine protein is an important sign of preeclampsia which is caused by the kidney tubules not having optimal capacity to absorb protein. Based on research by Wulandari et al (2022) which states that there is a significant relationship between urine protein and blood pressure levels in TM III pregnant women at the Madukara I Banjarnegara Community Health Center with p=0.003. The aim of the study was to determine the relationship between the incidence of hypertension and urine protein in pregnant women in TM III at RSUD dr. Soedirman Kebumen. The research method used Observational Analytical through a Cross-Sectional design with a sample of 40 people, carried out in May - July 2023 at the Laboratory of RSUD dr. Soedirman Kebumen. Based on this research, a value of p=0.052 (p>0.05) was obtained, so it can be concluded that there is no significant relationship between the incidence of hypertension and urine protein in TM III pregnant women at Dr. Soedirman Hospital, Kebumen. Keywords: Hypertension, Third Trimester pregnant women, urine protein.
Co-Authors Dita Pratiwi Kusuma Wardani Dwiar Apriyanti Feliatra Imam Sudarso Minto Rahaju Nurmalita Putri Nugrahena Retno Sulistiyowati Shely Ayu Lestari