Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Atom Indonesia Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Indonesian Journal of Cancer Indonesian Journal of Physics and Nuclear Applications ASEAN Journal on Science and Technology for Development Indonesian Journal of Cancer
Bagaswoto Poedjomartono Bagaswoto Poedjomartono
Department Of Radiology, Radionuclear Services, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia; Dr. Sardjito General Hospital, Jalan Kesehatan No. 1, Yogyakarta 55281, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health

Published : 14 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : ASEAN Journal on Science and Technology for Development

 1 
Boron Neutron Capture Therapy for Cancer: Future Prospects in Indonesia Bagaswoto Poedjomartono; Hanif Afkari; Edy Meiyanto; Alan Bangun; Yohanes Sardjono
ASEAN Journal on Science and Technology for Development Vol. 35 No. 3 (2018): Developments in Nuclear Techniques in the Treatment of Cancer
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29037/ajstd.510

Abstract

Boron neutron capture therapy (BNCT) is a form of cancer therapy based on the interaction of low-energy thermal neutrons and boron-10 (10-B) to produce alpha radiation from He-4 and Li-7 with a high linear energy transfer. A beam of neutrons irradiates a boron drug injected into the tumor, resulting in the boron-injected cancer cells receiving a lethal dose of radiation with the surrounding, healthy cells being minimally affected. Two boron drugs have been used clinically in BNCT, boron sodium captate (BSH) and borophenylalanine (BPA), while a third, pentagamaboronon-0 (PGB-0), is currently under development in the Faculty of Pharmacy of Universitas Gadjah Mada, Indonesia. In Indonesia, there has been a growing interest in the study and use of BNCT to treat cancer, as this method is expected to be safer and more effective than traditional cancer treatment methods.
Overview of Boron Neutron Capture Therapy: a Medical Aspect Alan Anderson Bangun; Bagaswoto Poedjomartono
ASEAN Journal on Science and Technology for Development Vol. 35 No. 3 (2018): Developments in Nuclear Techniques in the Treatment of Cancer
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1010.558 KB) | DOI: 10.29037/ajstd.512

Abstract

Cancer is an abnormal growth of a cell due to the cell’s inability to control and maintain its proliferation, differentiation and apoptosis cycle. There are several methods to treat cancer; one of which is boron neutron capture therapy (BNCT). BNCT is a radiation modality by which a high radiation dose is delivered to tumor cells with lower damage to surrounding normal tissue. This modality has been used widely as a treatment for several cancer cases, such as head and neck cancer, breast cancer, and liver cancer. BNCT uses sodium borocaptate (BSH) or boronophenylalanine (BPA) as the delivery agent. Then, the tumor cell is irradiated by thermal radiation. This technique has excellent potential to become a main method of cancer therapy in the future, since it is noninvasive and has fewer side effects than other methods. Further studies on BNCT are needed to improve its performance as a cancer treatment modality.
Co-Authors Ahmad Faiz, Ahmad Alan Anderson Bangun Alan Anderson Bangun Alan Anderson Bangun Alan Bangun E. Purwanti Edy Meiyanto Frinces, Freshilla Sonia Hanif Afkari Indrarto, Erwin Yudhistira Yasanusaraharja J. Sumanto P Pramiadi R. Isaris Rifki Bachtiar Sista Dyah Wijaya Sudarmanto - Sudarmanto -, Sudarmanto Suharni Suharni Yohanes Sardjono Yohannes Sardjono