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All Journal Nexus Biomedika Ijaz Arabi Journal of Arabic Learning
M Abdul Basith
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Biochemistry, Genetics & Molecular Biology Languange, Linguistic, Communication & Media

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Efek Nefroprotektor Ekstrak Daun Kemangi (Ocimum sanctum) Terhadap Kerusakan Sel Ginjal Mencit (Mus musculus) Yang Diinduksi Parasetamol Basith, M Abdul; Listyaningsih, Endang; Handayani, Selfi
Nexus Biomedika Vol 1, No 2 (2012): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13.86 KB)

Abstract

Background: Today, consuming paracetamol as an analgesic antipyretic drugs has  increased. Paracetamol which used in inappropriate dose has bad effect to our body, such as nefrotoxic. Basil leaf extract has antioxidant as a protection of free radicals and reducing NAPQI which produced by paracetamol. The objectives of this research are to know the nefroprotector effect and this research will shown the multilevel dose of basil leaf extract as a nefroprotector in the renal cell damage induced by parasetamol. Methods: This was experimental laboratory with the post test only controlled group design. Sample group consisted of male mice Swiss Webster, 2-3 month, + 20 g. Samples divided into 4 groups, each group has seven mice. Mice for control group (K) and the first treatment group (P1) were given aquades for 14 days. The second treatment group (P2) will be given basil leaf extract dose I for 14 days. The third treatment group (P3) will be given basil leaf extract dose II for 14 days. Paracetamol will be given to P1, P2, and P3, with dose 0,1 ml/20 gr weight of mice on the day 12, 13, and 14. Finally on day 15th, mice are sacrificed with neck dislocation then the renal of mice was made preparations with paraffin blocks methods and Hematoxillin Eosin staining. Renal cell damage observed and counted a mount of scored on renal histological karyopyknosis, karyorrhexis, and karyolysis. Data are analized by One-Way ANOVA test (α= 0,05) and continued by Post Hoc Multiple Comparisons test (LSD) (α = 0,05). Results: Result of One-Way ANOVA shown that there was a significant of degree between 4 groups. Result of LSD method there was a significant of degree between K-P1, K-P2, P1-P2, and P1-P3 groups; and also it wasn’t a significant of degree between K-P3 and P2-P3. Conclusions: The basil leaf extracts was able to decrease the renal cell damaging of mice and the increase of basil leaf extracts dose followed by the increase of protection effect to the renal cell damaging of mice which is induced by paracetamol.   Keywords: basil leaf extract, paracetamol, renal cell damage. 
Efek Nefroprotektor Ekstrak Daun Kemangi (Ocimum sanctum) Terhadap Kerusakan Sel Ginjal Mencit (Mus musculus) Yang Diinduksi Parasetamol M Abdul Basith; Endang Listyaningsih; Selfi Handayani
Nexus Biomedika Vol 1, No 2 (2012): Nexus Biomedika
Publisher : Nexus Biomedika

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Today, consuming paracetamol as an analgesic antipyretic drugs has increased. Paracetamol which used in inappropriate dose has bad effect to our body, such as nefrotoxic. Basil leaf extract has antioxidant as a protection of free radicals and reducing NAPQI which produced by paracetamol. The objectives of this research are to know the nefroprotector effect and this research will shown the multilevel dose of basil leaf extract as a nefroprotector in the renal cell damage induced by parasetamol. Methods: This was experimental laboratory with the post test only controlled group design. Sample group consisted of male mice Swiss Webster, 2-3 month, + 20 g. Samples divided into 4 groups, each group has seven mice. Mice for control group (K) and the first treatment group (P1) were given aquades for 14 days. The second treatment group (P2) will be given basil leaf extract dose I for 14 days. The third treatment group (P3) will be given basil leaf extract dose II for 14 days. Paracetamol will be given to P1, P2, and P3, with dose 0,1 ml/20 gr weight of mice on the day 12, 13, and 14. Finally on day 15th, mice are sacrificed with neck dislocation then the renal of mice was made preparations with paraffin blocks methods and Hematoxillin Eosin staining. Renal cell damage observed and counted a mount of scored on renal histological karyopyknosis, karyorrhexis, and karyolysis. Data are analized by One-Way ANOVA test (?= 0,05) and continued by Post Hoc Multiple Comparisons test (LSD) (? = 0,05). Results: Result of One-Way ANOVA shown that there was a significant of degree between 4 groups. Result of LSD method there was a significant of degree between K-P1, K-P2, P1-P2, and P1-P3 groups; and also it wasnt a significant of degree between K-P3 and P2-P3. Conclusions: The basil leaf extracts was able to decrease the renal cell damaging of mice and the increase of basil leaf extracts dose followed by the increase of protection effect to the renal cell damaging of mice which is induced by paracetamol. Keywords: basil leaf extract, paracetamol, renal cell damage.
The Role Of Discussion Method In Enhancing Speaking Skills Among Undergraduate Arabic Students At The New College Chennai Zubair K M A, Ahamed; Ali, M.Yasar Arafath; Lebbai, Nahvi Muhiyadeen; Basith, M Abdul; Yousuf, R. Md.
Ijaz Arabi Journal of Arabic Learning Vol 8, No 1 (2025): Ijaz Arabi: Journal Of Arabic Learning
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/ijazarabi.v8i1.30424

Abstract

The impact of the discussion method on the speaking skills of undergraduate Arabic students at The New College, Chennai, India, warrants a thorough examination. This study aims to determine how significantly the discussion method affects students' speaking abilities. It employs a quantitative research approach using a saturated sampling technique, with research instruments including questionnaires, interviews, and documentation, encompassing 26 Arabic undergraduate students from the 2022-25 cohort. The findings indicate that implementing the discussion method in teaching Speaking Skills effectively engaged students' interest in learning and was relatively easy to follow. According to the results of the T-test, the calculated value (t_hitung) is 9.648, which exceeds the table value (t_table) of 2.056 at a significance level of 0.025. Hence, the alternative hypothesis (Ha) is accepted. In contrast, the null hypothesis (Ho) is rejected, concluding that the discussion method positively influences the Speaking Skills of undergraduate students at The New College, Chennai. Additionally, the coefficient of determination test yielded a result of 0.782, indicating that the discussion method accounts for 78.2% of the variance in Speaking Skills.
Co-Authors Ali, M.Yasar Arafath Endang Listyaningsih Endang Listyaningsih Lebbai, Nahvi Muhiyadeen Selfi Handayani Yousuf, R. Md. Zubair K M A, Ahamed