Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Kolaboratif Sains
Endang Sjamsudin
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Other

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Effect of Extraction Method and Solvent Type on Total Phenolics Content, Total Flavonoid and Antioxidant Activity of Pegagan Extract (Centella asiatica (Linn.) Urban) Riza, Ahyar; Syafruddin Ilyas; Endang Sjamsudin; Delyuzar Delyuzar
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 1 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i1.902

Abstract

Background: Centella asiatica (CA) or pegagan or horse foot leaves is one of the traditional plants widely used to treat various diseases. This study aims to evaluated the content of total phenolics and total flavonoids, as well as the antioxidant activity of Centella asiatica extracts from different methods and solvents. Methods: The sample was divided into three groups, (70% ethanol maceration, methanol maceration and water infundation). Total phenolic compounds in the extract were determined by the Follin-Ciocalteu method, total flavonoid content was determined by the aluminum chloride colorimetric assay method, and antioxidant activity was assessed by the immersion DPPH free radicals method. Determination data of IC50 was assessed by regression test and differences between the three extract groups were tested by ANOVA or Kruskal Wallis test. Results: The highest total phenolics and total flavonoid were obtained in Centella asiatica extract with water solvent, 251.88 ± 0.96 mg/g GAE and 7.26 ± 0.03 mg/g QE, followed by 70% ethanol and methanol. In addition, the best antioxidant activity was also shown in the extract with water, namely 24.09 ± 0.01. The difference test results between all groups showed significant results (p<0.05) in all parameters. Conclusion: The best content of total phenolic, total flavonoid, and antioxidant activity was obtained by infundation with water solvent. In the maceration method, the best content of the three parameters measured was obtained in the group with ethanol solvent.
Effect of Extraction Method and Solvent Type on Total Phenolics Content, Total Flavonoid and Antioxidant Activity of Pegagan Extract (Centella asiatica (Linn.) Urban) Riza, Ahyar; Syafruddin Ilyas; Endang Sjamsudin; Delyuzar Delyuzar
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 1 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i1.902

Abstract

Background: Centella asiatica (CA) or pegagan or horse foot leaves is one of the traditional plants widely used to treat various diseases. This study aims to evaluated the content of total phenolics and total flavonoids, as well as the antioxidant activity of Centella asiatica extracts from different methods and solvents. Methods: The sample was divided into three groups, (70% ethanol maceration, methanol maceration and water infundation). Total phenolic compounds in the extract were determined by the Follin-Ciocalteu method, total flavonoid content was determined by the aluminum chloride colorimetric assay method, and antioxidant activity was assessed by the immersion DPPH free radicals method. Determination data of IC50 was assessed by regression test and differences between the three extract groups were tested by ANOVA or Kruskal Wallis test. Results: The highest total phenolics and total flavonoid were obtained in Centella asiatica extract with water solvent, 251.88 ± 0.96 mg/g GAE and 7.26 ± 0.03 mg/g QE, followed by 70% ethanol and methanol. In addition, the best antioxidant activity was also shown in the extract with water, namely 24.09 ± 0.01. The difference test results between all groups showed significant results (p<0.05) in all parameters. Conclusion: The best content of total phenolic, total flavonoid, and antioxidant activity was obtained by infundation with water solvent. In the maceration method, the best content of the three parameters measured was obtained in the group with ethanol solvent.
Unlocking the Jaw - Improving Quality of Life in Bilateral Fibrous Ankylosis of the Mandibular Condyle with Dual Surgical Approach : A Case Report: Membuka Kunci Rahang - Meningkatkan Kualitas Hidup pada Ankylosis Fibrosa Bilateral Kondil Mandibula dengan Pendekatan Bedah Ganda: Laporan Kasus Marini Sundari; Eka Marwansyah Oli`i; Endang Sjamsudin
Jurnal Kolaboratif Sains Vol. 9 No. 3: Maret 2026
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v9i3.10658

Abstract

Fibrous ankylosis of the mandibular condyles restricts jaw movement due to fibrous tissue adhesions in the temporomandibular joint (TMJ), leading to impaired oral function. Surgical management, especially condylectomy and coronoidectomy procedures, remains the most effective method of improving jaw function. A 12-year-old girl with a history of facial trauma and previous surgical intervention who developed progressive limitation in mouth opening over last three years. Clinical examination showed complete inability to open the mouth. Cone Beam Computed Tomography (CBCT) confirmed bilateral fibrous ankylosis of the mandible. The patient underwent bilateral preauricular surgical approaches, with excision of fibrous adhesions, bilateral condylectomies, and unilateral coronoidectomy. Mersilene mesh was placed bilaterally. Intensive physiotherapy was initiated after the surgery. At six months follow-up, the patient demonstrated significant improvement in jaw mobility. Fibrous ankylosis of the mandibular condyles can severely limit jaw function, especially in growing children. Surgical management successfully released the ankylosis and restored mandibular movement. Placement of Mersilene mesh helped prevent re-ankylosis, while early and intensive physiotherapy played a crucial role in maintaining postoperative mouth opening. Comprehensive surgical management combined with intensive postoperative rehabilitation is essential for effective treatment in patients with bilateral fibrous ankylosis of the mandibular condyles
Co-Authors Delyuzar, Delyuzar Eka Marwansyah Oli`i Marini Sundari Riza, Ahyar Syafruddin Ilyas