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All Journal As-syifaa Jurnal Farmasi Celebes Abdimas: Jurnal Pengabdian Kepada Masyarakat Journal of Pharmaceutical and Health Research INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Jurnal Multidisiplin Madani (MUDIMA) Medical Sains : Jurnal Ilmiah Kefarmasian Formosa Journal of Applied Sciences (FJAS) Pharmaceutical Reports Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Jurnal Kesehatan Cendikia Jenius Medical Sains : Jurnal Ilmiah Kefarmasian
Safaruddin
Universitas Megarezky
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Penentuan Nilai SPF (Sun Protection Factor) Sediaan Serum Anti-Aging Ekstrak Rimpang Galoba (Horstedtia Alliacceae) Safaruddin, Safaruddin; Suleman, Abdul Wahid; Zahira, Saliza
Journal of Pharmaceutical and Health Research Vol 5 No 3 (2024): October 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i3.5760

Abstract

The rhizome of Galoba (Horstedtia alliacceae) contains flavonoids, alkaloids, saponins, tannins, and triterpenoids which are secondary metabolite compounds that have antioxidant activity. The most antioxidants are flavonoids where antioxidants are used as anti-aging agents because free radicals are involved in the aging process of the skin. Objectives of the study to determine whether ethanol extract of galoba rhizome (Horstedtia alliacceae) can be formulated into a physically and chemically stable serum preparation, as well as to determine the SPF (Sun Protection Factor) value in serum preparations. The research method used an experimental method in vitro using a UV-Vis spectrophotometer, extraction by maceration method using 96% ethanol solvent, and then an anti-aging serum preparation formulation was made with concentrations of F1 (5%), F2 (10%), F3 (15%), F3 (20%). Then the SPF (Sun Protection Factor) value is determined. The results of the serum formula research showed that it was physically and chemically stable, which was marked by no difference before and after the cycling test, both in organoleptic, homogeneity, pH, viscosity, and humidity tests. The results of the SPF value of serum preparations at F1 (5%) were 4.51, F2 (10%) was 5.66, F3 (15%) was 8.67, and F4 (20%) was 13.06. The conclusion of this study is to show that Galoba rhizome extract (Hornstedtia alliacea) can be formulated into a physically and chemically stable anti-aging serum preparation, and the best SPF value obtained from the F4 formula (20%) is 13.06 with the maximum protection category.
Pemanfaatan Kolagen Tulang Ayam Broiler dalam Sediaan Serum: Nilai SPF, Eritema, Pigmentasi, Kelembapan Kulit Suleman, Abdul Wahid; Safaruddin, Safaruddin; Mustamin, Sharnawati; Wahyuningsih, Sri; Jannah, Miftahul
Journal of Pharmaceutical and Health Research Vol 6 No 3 (2025): October 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i3.8459

Abstract

Chicken bones (Gallus gallus domestica) are a type of solid waste that contain protein sources in the form of collagen. Collagen is one of the main connective tissue proteins in animals, widely used as a biomedical material, and is effective as an anti-aging agent that helps prevent the appearance of aging signs on the skin. This study aims to determine the potential of broiler chicken bone collagen in serum formulations as a photoprotective, anti-pigmentation, and skin moisturizing agent. The research method used was an in vitro experimental method using a UV-Vis spectrophotometer. Collagen was extracted using NaOH and CH₃COOH 1 M, and serum formulations were prepared with concentrations F1 (1%), F2 (1.5%), F3 (2%), and F4 (2.5%). The SPF value, erythema and pigmentation levels, as well as skin moisture, were then determined. The results of the serum formulation showed physical and chemical stability, indicated by no significant differences before and after the cycling test in organoleptic, pH, homogeneity, viscosity, and spreadability evaluations. The SPF values of the serum preparations were: F1 (1%) = 2.814999, F2 (1.5%) = 3.287317, F3 (2%) = 4.659954, and F4 (2.5%) = 8.574363. The %Te and %Tp tests showed that F0 (without extract) fell under the “Sunblock <1” category, while F1, F2, F3, and F4 were categorized as “Fast tanning” with values between 45–86. In conclusion, this study demonstrates that chicken bone extract can be formulated into a serum preparation that is physically and chemically stable. The best SPF, %Te, and %Tp values were obtained in the F4 formula, categorized as optimal, with %Te and %Tp values in the fast tanning category. Additionally, the F4 formula increased skin moisture by 5%.
Hubungan Pengetahuan dan Sikap terhadap Perilaku Pencegahan TB Paru di Wilayah Kerja Puskesmas Palakka Bupaten Barru: The Relationship of Knowledge and Attitude to Preventing Behavior of Lung TB in the Work Area of Palakka Puskesmas, Barru Regency Safaruddin; Muhammad Aris
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 6 No. 1 (2023)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v6i1.2989

Abstract

Latar belakang: Berdasarkan survey awal yang dilakukan di puskesmas palakka pada pasien tuberculosis bahwa belum terlalu paham mengenai pencegahan terjadinya TB dan kurangnya wawasan terhadap TB serta sikap dan perilaku dalam mencegah penularan TB sangatlah kurang Tujuan : Untuk mengetahui hubungan pengetahuan dan sikap terhadap perilaku pencegahan TB paru di di wilayah kerja puskesmas palakka kabupaten barru. Metode: Penelitian ini menggunakan penelitian survei dengan pendekatan Cross Sectional Studydimana peneliti melakukan observasi atau pengukuran variabel pada suatu saat (point time approach). Hasil: Data yang diperoleh akan diolah dengan menggunakan statistik berdasarkan skala ukur variabel dan penyajian dalam tabel disertai penjelasan. Kesimpulan: Ada Hubungan Pengetahuan Terhdap Pencegahan TB Paru Di Wilayah Kerja Puskesmas Palakka Bupaten Barru, Ada Hubungan Sikap Terhdap Pencegahan Tb Paru Di Wilayah Kerja Puskesmas Palakka Bupaten Barru.
Formulasi dan Uji Aktivitas Sediaan Salep Anti Jerawat Ekstrak Etanol Bunga Kenop (Gomphrena globosa) terhadap Staphylococcus aureus Abdul Wahid Suleman; Muhammad Yusuf; Safaruddin Safaruddin; Rizky Indah Pratiwi
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 7 No. 2 (2023)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v7i2.3277

Abstract

Bunga kenop (Gomphrena globosa) mengandung senyawa flavonoid, saponin dan tanin yang dapat berfungsi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui ekstrak etanol bunga kenop dapat dibuat dalam bentuk formulasi sediaan salep anti jerawat yang stabil secara fisika dan kimia serta aktivitas sediaan sebagai anti jerawat terhadap Staphylococcus aureus. Metode penelitian ini dilakukan secara eksperimental, dengan membuat sediaan salep anti jerawat dari ekstrak etanol bunga kenop dengan variasi konsentrasi yaitu F1 (konsentrasi 7%), F2 (konsentrasi 8%), F3 (konsentrasi 9%), F4 (kontrol negatif), F5 (kontrol positif) dan menguji aktivitas sediaan terhadap Staphylococcus aureus menggunakan metode sumuran. Hasil penelitian menunjukkan bahwa formula salep anti jerawat ekstrak etanol Bunga Kenop stabil secara fisik dan kimia dan tidak terdapat perbedaan bermakna (p<0,05) sebelum dan sesudah Cycling test baik pada uji organoleptik, homogenitas, pH, daya sebar, daya lekat, dan viskositas. Pengujian aktivitas anti jerawat terhadap Staphylococcus aureus menunjukkan bahwa F1 (7%) diameter zona hambat 10,2±0,15 mm, F2 (8%) diameter zona hambat 10,9±0,50 mm, F3 (9%) diameter zona hambat 11,4±0,52 mm, F4 (K-) diameter zona hambat 0±0,00 mm, dan F5 (K+) diameter zona hambat 16,2±0,52 mm. Dari hasil yang diperoleh dapat disimpulkan bahwa ekstrak bunga kenop dapat dibuat dalam bentuk formulasi sediaan salep yang memiliki aktivitas antijerawat terhadap Staphylococcus aureus pada konsentrasi 7%, 8%, dan 9%
Pharmacoeconomic Analysis of Antidiabetic Therapy in Patients with Type 2 Diabetes Mellitus Safaruddin; Salbia; Putri Indah Sari; Rahmasinar Amin
Jurnal Kesehatan Cendikia Jenius Vol. 3 No. 3 (2026): Agustus 2026
Publisher : CV. CENDIKIA JENIUS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70920/jenius.v3i3.442

Abstract

Type 2 diabetes mellitus is a chronic disease with a continuously increasing prevalence and requires long-term therapy, resulting in a substantial financial burden. Pharmacoeconomic evaluation is therefore needed to assess the efficiency of antidiabetic therapy at Daya Regional General Hospital, Makassar City. This study aimed to analyze treatment costs, examine the relationship between treatment costs and treatment duration, and identify the most efficient therapy based on the Average Cost-Effectiveness Ratio (ACER) among patients with type 2 diabetes mellitus. This study employed a quantitative descriptive-analytical method with a retrospective approach involving 69 patients with type 2 diabetes mellitus treated from January to February 2026. Data were analyzed using Cost of Illness (COI), Cost-Effectiveness Analysis (CEA), and Spearman’s correlation test. The results showed that the average treatment cost per patient was IDR 576,170.65. A significant positive correlation was found between treatment duration and treatment cost (r = 0.239; p = 0.048). Single-drug therapy had the lowest ACER value of IDR 1,117,506.50 and the highest proportion of controlled HbA1c levels at 38.9%. In conclusion, single-drug therapy using oral antidiabetic drugs was the most cost-effective treatment option for patients with type 2 diabetes mellitus at Daya Regional General Hospital, Makassar, as it provided the highest clinical effectiveness at an affordable cost. It is recommended that pharmacoeconomic evaluation be one of the considerations in selecting antidiabetic therapy to obtain optimal clinical results at a more efficient cost.
Co-Authors A. Nurnadya Arna Abdul Wahid Suleman Asti Vebriyanti Asjur Besse Yuliana Elvira Santi Hadrianti H. D. Lasari Imran Firman Imran Firman Ka’bah Ka’bah M. Yogi Riyantama Isjoni Mansyur S Marwah S Marwah S Miftahul Jannah Mike Arum Mirfaidah Nadjamuddin Muh. Reski Salemuddin Muhammad Aris Muhammad Yusuf Mustamin, Sharnawati Nurhidayati M. Syahdan Nurisrah Nurisrah Putri Indah Sari Rahmahsinar Amin Rahmasinar Amin Rizky Indah Pratiwi Salbia Sri Wahyuningsih Ummu Kalsum Wahyuddin Jumardin Zahira, Saliza