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All Journal As-syifaa Jurnal Farmasi Celebes Abdimas: Jurnal Pengabdian Kepada Masyarakat Journal of Pharmaceutical and Health Research Jurnal Multidisiplin Madani (MUDIMA) Medical Sains : Jurnal Ilmiah Kefarmasian Formosa Journal of Applied Sciences (FJAS) Pharmaceutical Reports Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Medical Sains : Jurnal Ilmiah Kefarmasian
Safaruddin
Universitas Megarezky
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Penentuan Nilai SPF (Sun Protection Factor) Sediaan Serum Anti-Aging Ekstrak Rimpang Galoba (Horstedtia Alliacceae) Safaruddin, Safaruddin; Suleman, Abdul Wahid; Zahira, Saliza
Journal of Pharmaceutical and Health Research Vol 5 No 3 (2024): October 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i3.5760

Abstract

The rhizome of Galoba (Horstedtia alliacceae) contains flavonoids, alkaloids, saponins, tannins, and triterpenoids which are secondary metabolite compounds that have antioxidant activity. The most antioxidants are flavonoids where antioxidants are used as anti-aging agents because free radicals are involved in the aging process of the skin. Objectives of the study to determine whether ethanol extract of galoba rhizome (Horstedtia alliacceae) can be formulated into a physically and chemically stable serum preparation, as well as to determine the SPF (Sun Protection Factor) value in serum preparations. The research method used an experimental method in vitro using a UV-Vis spectrophotometer, extraction by maceration method using 96% ethanol solvent, and then an anti-aging serum preparation formulation was made with concentrations of F1 (5%), F2 (10%), F3 (15%), F3 (20%). Then the SPF (Sun Protection Factor) value is determined. The results of the serum formula research showed that it was physically and chemically stable, which was marked by no difference before and after the cycling test, both in organoleptic, homogeneity, pH, viscosity, and humidity tests. The results of the SPF value of serum preparations at F1 (5%) were 4.51, F2 (10%) was 5.66, F3 (15%) was 8.67, and F4 (20%) was 13.06. The conclusion of this study is to show that Galoba rhizome extract (Hornstedtia alliacea) can be formulated into a physically and chemically stable anti-aging serum preparation, and the best SPF value obtained from the F4 formula (20%) is 13.06 with the maximum protection category.
Pemanfaatan Kolagen Tulang Ayam Broiler dalam Sediaan Serum: Nilai SPF, Eritema, Pigmentasi, Kelembapan Kulit Suleman, Abdul Wahid; Safaruddin, Safaruddin; Mustamin, Sharnawati; Wahyuningsih, Sri; Jannah, Miftahul
Journal of Pharmaceutical and Health Research Vol 6 No 3 (2025): October 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i3.8459

Abstract

Chicken bones (Gallus gallus domestica) are a type of solid waste that contain protein sources in the form of collagen. Collagen is one of the main connective tissue proteins in animals, widely used as a biomedical material, and is effective as an anti-aging agent that helps prevent the appearance of aging signs on the skin. This study aims to determine the potential of broiler chicken bone collagen in serum formulations as a photoprotective, anti-pigmentation, and skin moisturizing agent. The research method used was an in vitro experimental method using a UV-Vis spectrophotometer. Collagen was extracted using NaOH and CH₃COOH 1 M, and serum formulations were prepared with concentrations F1 (1%), F2 (1.5%), F3 (2%), and F4 (2.5%). The SPF value, erythema and pigmentation levels, as well as skin moisture, were then determined. The results of the serum formulation showed physical and chemical stability, indicated by no significant differences before and after the cycling test in organoleptic, pH, homogeneity, viscosity, and spreadability evaluations. The SPF values of the serum preparations were: F1 (1%) = 2.814999, F2 (1.5%) = 3.287317, F3 (2%) = 4.659954, and F4 (2.5%) = 8.574363. The %Te and %Tp tests showed that F0 (without extract) fell under the “Sunblock <1” category, while F1, F2, F3, and F4 were categorized as “Fast tanning” with values between 45–86. In conclusion, this study demonstrates that chicken bone extract can be formulated into a serum preparation that is physically and chemically stable. The best SPF, %Te, and %Tp values were obtained in the F4 formula, categorized as optimal, with %Te and %Tp values in the fast tanning category. Additionally, the F4 formula increased skin moisture by 5%.
Co-Authors A. Nurnadya Arna Abdul Wahid Suleman Asti Vebriyanti Asjur Besse Yuliana Elvira Santi Hadrianti H. D. Lasari Imran Firman Imran Firman Ka’bah Ka’bah M. Yogi Riyantama Isjoni Mansyur S Marwah S Marwah S Miftahul Jannah Mike Arum Mirfaidah Nadjamuddin Muh. Reski Salemuddin Mustamin, Sharnawati Nurhidayati M. Syahdan Nurisrah Nurisrah Rahmahsinar Amin Rizky Indah Pratiwi Sri Wahyuningsih Ummu Kalsum Wahyuddin Jumardin Zahira, Saliza