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All Journal Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming SANITAS: Jurnal Teknologi dan Seni Kesehatan Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Yetri Elisya
Politeknik Kesehatan Kemenkes Jakarta II
Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Environmental Science Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Physics Public Health

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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

 1 
IDENTIFIKASI DAN UJI ANTI KANKER TABLET EKSTRAK DAUN PALIASA (KLEINHOVIA HOSPITA LINN) SECARA MTT ASSAY Yetri Elisya; Junaedi Junaedi; Maratu Saleha
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.519 KB) | DOI: 10.36387/jiis.v7i1.859

Abstract

Indonesia has several plants that can be developed into cancer drugs. This study aims to make tablet preparations containing Paliasa leaf extract to produce pharmaceutical preparations for anticancer use. Paliasa leaves were extracted by maceration using 70% alcohol; then, the tablets were made using the wet granulation method. The extract obtained from 2,207 kg of dried simplicia paliasa leaves was 542 grams, with a yield of 24.56%. The flavonoid content in the extract was 1.79%, and the tablet was 0.75%. There are active compounds, namely 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl, a powerful antioxidant blend, hexadecanoic acid, or palmitic acid functions as an antibacterial and antioxidant, and kaempferol is one of the compounds, which has potential as an anticancer. The identification of extracts and tablets of paliasa leaf (Kleinhovia hospital Linn) resulted in IC50 above > 30 ppm in the inactive category, so the bioactivity of paliasa leaf extract was studied further fractionation.
UJI AKTIVITAS ANTI-AGING KRIM TABIR SURYA KOMBINASI EKSTRAK TONGKOL JAGUNG (Zea mays L.) DAN EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora Pierre Ex. A. Froehner) Harpolia Cartika; Yetri Elisya; Fatwa Hasbi; Khairun Nida
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.535 KB) | DOI: 10.36387/jiis.v7i1.863

Abstract

Skin aging which is characterized by wrinkles and reduced skin moisture due to sun exposure can be prevented by using sunscreen preparations. The sunscreen cream combination of corn cob extract and robusta coffee bean extract has strong antioxidant activity and extra protection, so it has the potential as anti-aging. This study aims to determine the anti-aging activity of the test cream. Research using experimental methods. The sunscreen cream contains 10% corn cob extract and 15% robusta coffee bean extract. Physical testing and cream stability using the cycling test method. The anti-aging activity of the cream was tested in vivo using female Sprague-Dawley rats, the observations were continued by SEM, the parameter was wrinkles. The results of the evaluation of physical stability meet the requirements of the cream. Details of the average score of wrinkles on the skin of the feet of rats given a cream base of 2.5, a test cream of 1.5 and a comparison cream of 1. This indicates the test cream has the potential as an anti-aging.
Co-Authors Adin Hakim Kurniawan Anindita Rizkiana Cartika, Harpolia Cessa Lynatra Fatwa Hasbi Fikri Alamysah Junaedi Junaedi Khairun Nida Maratu Saleha Muhamad Irfan Nanda Puspita Wardiyah, Wardiyah