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Invivo Effect Analysis of Rhodomyrtus tomentosa Leaf Ethanol Extract Against Escherichia coli Doris Noviani; Adisty Dwi Treasa; Ade Zakiya Tasman Munaf; Sri Winarsih; Dwi Yuni Nur Hidayati; Mukhamad Nooryanto; Sutrisno Sutrisno
Medical Laboratory Technology Journal Vol. 7 No. 1 (2021): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.79 KB) | DOI: 10.31964/mltj.v7i1.392

Abstract

Puerperium infection contributed 11 percent of 48.17 percent of maternal mortality during the puerperium period; one of the causes of increased risk of puerperium infection was bacteria Gram-negative Escherichia coli. Puerperium infection occurred because bacteria enter through the vagina, wounds on the insertion of the placenta, and other parts spread to blood throughout the body and damage the spleen, liver, and uterus. This research aimed to determine the effect of Rhodomyrtus tomentosa leaves ethanol extract (Rtl-EE) as an antibacterial on the spleen, liver, and uterus of Escherichia coli -induced puerperal infection model mice. Mice in the postnatal treatment group were induced by Escherichia coli bacteria intravaginally and given different doses of ethanol extract of Rhodomyrtus tomentosa leaves. Examination of bacterial colonies growth used pour plate method with EMBA media. The research results showed that the administration of Rtl-EE decreased the growth of bacterial colonies respectively in the liver 1280, 924, 330 CFU/mL; the uterus 1806, 1180, 874 CFU/mL; and the spleen 712, 112, 774 CFU/mL. Colony growth started to decrease at dose 1 of Rtl-EE (100mg/kg BW) of mice model of Escherichia coli -induced puerperal infection. Rhodomyrtus tomentosa leaves contain active compounds - phenols, flavonoids, saponins, tannins, alkaloids, and triterpenoids as antibacterial. Rtl-EE had an antibacterial effect by reducing the number of bacteria on the spleen, liver, and uterus of Escherichia coli -induced puerperal infection model mice. Further research needs to conduct to examine the toxic dose of Rhodomyrtus tomentosa leaves against Escherichia coli bacteria.
HUBUNGAN DUKUNGAN SUAMI TERHADAP TINGKAT KECEMASAN IBU PADA SAAT PERSALINAN DI KLINIK MITRA ANANDA PALEMBANG Vera Yuanita; Yuli Suryanti; Adisty Dwi Treasa
Jurnal Kesehatan dan Pembangunan Vol 14 No 2 (2024): Jurnal Kesehatan dan Pembangunan
Publisher : LPPM STIKes Mitra Adiguna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52047/jkp.v14i2.346

Abstract

WHO estimates that the Maternal Mortality Rate (MMR) is still very high. Around 287,000 women died during and after pregnancy and childbirth in 2020. In the labor phase there is also an increase in anxiety, with increasing anxiety the intensity of pain will increase. When experiencing anxiety during childbirth, family support is really needed by pregnant women so they can comfort and calm them. The aim of the research was to determine the relationship between husband's support and maternal anxiety levels during childbirth at the Mitra Ananda Clinic in Palembang in 2023. The research method used a cross sectional method. The population in this study were all mothers giving birth at the Mitra Ananda Clinic in Palembang with a sample size of 35 respondents. The research results showed that the distribution of frequency of support from husbands was mostly 20 respondents (57.1%), the mother's anxiety level during childbirth was mostly mild anxiety, 14 respondents (40%). There is a significant relationship between husband's support and the mother's anxiety level during childbirth at the Mitra Ananda Clinic in Palembang in 2023 (p.value = 0.011). Suggestions are expected to further increase the husband's role in the wife's birth by providing counseling to the husband starting when the wife is pregnant to pay more attention to the wife's health condition from the beginning of pregnancy until before delivery.